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A8MCX6

- TF2B_CALMQ

UniProt

A8MCX6 - TF2B_CALMQ

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Protein
Transcription initiation factor IIB
Gene
tfb, Cmaq_0797
Organism
Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) By similarity.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi45 – 451Zinc By similarity
Metal bindingi48 – 481Zinc By similarity
Metal bindingi64 – 641Zinc By similarity
Metal bindingi67 – 671Zinc By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri41 – 7232TFIIB-typeUniRule annotation
Add
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. DNA-templated transcription, initiation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciCMAQ397948:GH9M-817-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription initiation factor IIB
Short name:
TFIIB
Gene namesi
Name:tfb
Ordered Locus Names:Cmaq_0797
OrganismiCaldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Taxonomic identifieri397948 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeCaldivirga
ProteomesiUP000001137: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 336336Transcription initiation factor IIBUniRule annotation
PRO_1000080104Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi397948.Cmaq_0797.

Structurei

3D structure databases

ProteinModelPortaliA8MCX6.
SMRiA8MCX6. Positions 45-85.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati152 – 235841UniRule annotation
Add
BLAST
Repeati246 – 327822UniRule annotation
Add
BLAST

Sequence similaritiesi

Belongs to the TFIIB family.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG1405.
HOGENOMiHOG000108633.
KOiK03124.
OMAiCDSQNIS.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
HAMAPiMF_00383. TF2B_arch.
InterProiIPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERiPTHR11618. PTHR11618. 1 hit.
PfamiPF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSiPR00685. TIFACTORIIB.
SMARTiSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
PROSITEiPS00782. TFIIB. 1 hit.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8MCX6-1 [UniParc]FASTAAdd to Basket

« Hide

MSTTQGGSNQ QDETRRELII QKFKLFRREG NNLEFVDQSG QKLRCPICGN    50
TVFIEDAERG QIVCASCGYV LMEHILDTGP EWRAFTPEEK EDRARTGGPL 100
ERVTSEELVT RIETTLKSPD LKKKLEILKY KKWQQRIRVQ TSYERNLVQA 150
THELNRIAHQ LGVPKSCMDE ALAVYKQVLK SGLVKGRSVE AIIAACLHMA 200
CRMQGMPRSL DEISQYTRAP RKEIARCFRL IARELRIRLP LSDPRQYVPK 250
IVEQLKLPGD IAKEAIRVLE EAKDKGLTAG KDPAGLAAAA VYIASLLKGE 300
VRTQKEIAQA AQVTEVTVRN RYKELAKELN IKIPIK 336
Length:336
Mass (Da):38,078
Last modified:December 4, 2007 - v1
Checksum:iE87913321A7C1357
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000852 Genomic DNA. Translation: ABW01632.1.
RefSeqiYP_001540622.1. NC_009954.1.

Genome annotation databases

EnsemblBacteriaiABW01632; ABW01632; Cmaq_0797.
GeneIDi5710362.
KEGGicma:Cmaq_0797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000852 Genomic DNA. Translation: ABW01632.1 .
RefSeqi YP_001540622.1. NC_009954.1.

3D structure databases

ProteinModelPortali A8MCX6.
SMRi A8MCX6. Positions 45-85.
ModBasei Search...

Protein-protein interaction databases

STRINGi 397948.Cmaq_0797.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABW01632 ; ABW01632 ; Cmaq_0797 .
GeneIDi 5710362.
KEGGi cma:Cmaq_0797.

Phylogenomic databases

eggNOGi COG1405.
HOGENOMi HOG000108633.
KOi K03124.
OMAi CDSQNIS.

Enzyme and pathway databases

BioCyci CMAQ397948:GH9M-817-MONOMER.

Family and domain databases

Gene3Di 1.10.472.10. 2 hits.
HAMAPi MF_00383. TF2B_arch.
InterProi IPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view ]
PANTHERi PTHR11618. PTHR11618. 1 hit.
Pfami PF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view ]
PRINTSi PR00685. TIFACTORIIB.
SMARTi SM00385. CYCLIN. 2 hits.
[Graphical view ]
SUPFAMi SSF47954. SSF47954. 2 hits.
PROSITEi PS00782. TFIIB. 1 hit.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700844 / DSM 13496 / JCM 10307 / IC-167.

Entry informationi

Entry nameiTF2B_CALMQ
AccessioniPrimary (citable) accession number: A8MCX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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