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A8MCX6 (TF2B_CALMQ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription initiation factor IIB

Short name=TFIIB
Gene names
Name:tfb
Ordered Locus Names:Cmaq_0797
OrganismCaldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167) [Complete proteome] [HAMAP]
Taxonomic identifier397948 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeCaldivirga

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) By similarity. HAMAP-Rule MF_00383

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00383

Sequence similarities

Belongs to the TFIIB family.

Contains 1 TFIIB-type zinc finger.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Transcription initiation factor IIB HAMAP-Rule MF_00383
PRO_1000080104

Regions

Repeat152 – 235841 HAMAP-Rule MF_00383
Repeat246 – 327822 HAMAP-Rule MF_00383
Zinc finger41 – 7232TFIIB-type HAMAP-Rule MF_00383

Sites

Metal binding451Zinc By similarity
Metal binding481Zinc By similarity
Metal binding641Zinc By similarity
Metal binding671Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A8MCX6 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: E87913321A7C1357

FASTA33638,078
        10         20         30         40         50         60 
MSTTQGGSNQ QDETRRELII QKFKLFRREG NNLEFVDQSG QKLRCPICGN TVFIEDAERG 

        70         80         90        100        110        120 
QIVCASCGYV LMEHILDTGP EWRAFTPEEK EDRARTGGPL ERVTSEELVT RIETTLKSPD 

       130        140        150        160        170        180 
LKKKLEILKY KKWQQRIRVQ TSYERNLVQA THELNRIAHQ LGVPKSCMDE ALAVYKQVLK 

       190        200        210        220        230        240 
SGLVKGRSVE AIIAACLHMA CRMQGMPRSL DEISQYTRAP RKEIARCFRL IARELRIRLP 

       250        260        270        280        290        300 
LSDPRQYVPK IVEQLKLPGD IAKEAIRVLE EAKDKGLTAG KDPAGLAAAA VYIASLLKGE 

       310        320        330 
VRTQKEIAQA AQVTEVTVRN RYKELAKELN IKIPIK 

« Hide

References

[1]"Complete sequence of Caldivirga maquilingensis IC-167."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ivanova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M., Saltikov C., House C.H., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700844 / DSM 13496 / JCM 10307 / IC-167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000852 Genomic DNA. Translation: ABW01632.1.
RefSeqYP_001540622.1. NC_009954.1.

3D structure databases

ProteinModelPortalA8MCX6.
SMRA8MCX6. Positions 45-85.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING397948.Cmaq_0797.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABW01632; ABW01632; Cmaq_0797.
GeneID5710362.
KEGGcma:Cmaq_0797.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1405.
HOGENOMHOG000108633.
KOK03124.
OMACDSQNIS.

Enzyme and pathway databases

BioCycCMAQ397948:GH9M-817-MONOMER.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
HAMAPMF_00383. TF2B_arch.
InterProIPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERPTHR11618. PTHR11618. 1 hit.
PfamPF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSPR00685. TIFACTORIIB.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS00782. TFIIB. 1 hit.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTF2B_CALMQ
AccessionPrimary (citable) accession number: A8MCX6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families