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A8MCX6

- TF2B_CALMQ

UniProt

A8MCX6 - TF2B_CALMQ

Protein

Transcription initiation factor IIB

Gene

tfb

Organism
Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    • Comment

    Functioni

    Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi45 – 451ZincUniRule annotation
    Metal bindingi48 – 481ZincUniRule annotation
    Metal bindingi64 – 641ZincUniRule annotation
    Metal bindingi67 – 671ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri41 – 7232TFIIB-typeUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA-templated transcription, initiation Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciCMAQ397948:GH9M-817-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription initiation factor IIBUniRule annotation
    Short name:
    TFIIBUniRule annotation
    Gene namesi
    Name:tfbUniRule annotation
    Ordered Locus Names:Cmaq_0797
    OrganismiCaldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)
    Taxonomic identifieri397948 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeCaldivirga
    ProteomesiUP000001137: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 336336Transcription initiation factor IIBPRO_1000080104Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi397948.Cmaq_0797.

    Structurei

    3D structure databases

    ProteinModelPortaliA8MCX6.
    SMRiA8MCX6. Positions 45-85.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati152 – 235841Add
    BLAST
    Repeati246 – 327822Add
    BLAST

    Sequence similaritiesi

    Belongs to the TFIIB family.UniRule annotation
    Contains 1 TFIIB-type zinc finger.UniRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri41 – 7232TFIIB-typeUniRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG1405.
    HOGENOMiHOG000108633.
    KOiK03124.
    OMAiCDSQNIS.

    Family and domain databases

    Gene3Di1.10.472.10. 2 hits.
    HAMAPiMF_00383. TF2B_arch.
    InterProiIPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view]
    PANTHERiPTHR11618. PTHR11618. 1 hit.
    PfamiPF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view]
    PRINTSiPR00685. TIFACTORIIB.
    SMARTiSM00385. CYCLIN. 2 hits.
    [Graphical view]
    SUPFAMiSSF47954. SSF47954. 2 hits.
    PROSITEiPS00782. TFIIB. 1 hit.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8MCX6-1 [UniParc]FASTAAdd to Basket

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    MSTTQGGSNQ QDETRRELII QKFKLFRREG NNLEFVDQSG QKLRCPICGN    50
    TVFIEDAERG QIVCASCGYV LMEHILDTGP EWRAFTPEEK EDRARTGGPL 100
    ERVTSEELVT RIETTLKSPD LKKKLEILKY KKWQQRIRVQ TSYERNLVQA 150
    THELNRIAHQ LGVPKSCMDE ALAVYKQVLK SGLVKGRSVE AIIAACLHMA 200
    CRMQGMPRSL DEISQYTRAP RKEIARCFRL IARELRIRLP LSDPRQYVPK 250
    IVEQLKLPGD IAKEAIRVLE EAKDKGLTAG KDPAGLAAAA VYIASLLKGE 300
    VRTQKEIAQA AQVTEVTVRN RYKELAKELN IKIPIK 336
    Length:336
    Mass (Da):38,078
    Last modified:December 4, 2007 - v1
    Checksum:iE87913321A7C1357
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000852 Genomic DNA. Translation: ABW01632.1.
    RefSeqiYP_001540622.1. NC_009954.1.

    Genome annotation databases

    EnsemblBacteriaiABW01632; ABW01632; Cmaq_0797.
    GeneIDi5710362.
    KEGGicma:Cmaq_0797.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000852 Genomic DNA. Translation: ABW01632.1 .
    RefSeqi YP_001540622.1. NC_009954.1.

    3D structure databases

    ProteinModelPortali A8MCX6.
    SMRi A8MCX6. Positions 45-85.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 397948.Cmaq_0797.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABW01632 ; ABW01632 ; Cmaq_0797 .
    GeneIDi 5710362.
    KEGGi cma:Cmaq_0797.

    Phylogenomic databases

    eggNOGi COG1405.
    HOGENOMi HOG000108633.
    KOi K03124.
    OMAi CDSQNIS.

    Enzyme and pathway databases

    BioCyci CMAQ397948:GH9M-817-MONOMER.

    Family and domain databases

    Gene3Di 1.10.472.10. 2 hits.
    HAMAPi MF_00383. TF2B_arch.
    InterProi IPR013763. Cyclin-like.
    IPR000812. TFIIB.
    IPR023484. TFIIB_arc.
    IPR023486. TFIIB_CS.
    IPR013150. TFIIB_cyclin.
    IPR013137. Znf_TFIIB.
    [Graphical view ]
    PANTHERi PTHR11618. PTHR11618. 1 hit.
    Pfami PF08271. TF_Zn_Ribbon. 1 hit.
    PF00382. TFIIB. 2 hits.
    [Graphical view ]
    PRINTSi PR00685. TIFACTORIIB.
    SMARTi SM00385. CYCLIN. 2 hits.
    [Graphical view ]
    SUPFAMi SSF47954. SSF47954. 2 hits.
    PROSITEi PS00782. TFIIB. 1 hit.
    PS51134. ZF_TFIIB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700844 / DSM 13496 / JCM 10307 / IC-167.

    Entry informationi

    Entry nameiTF2B_CALMQ
    AccessioniPrimary (citable) accession number: A8MCX6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3