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A8MB38 (AROA_CALMQ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Cmaq_1850
OrganismCaldivirga maquilingensis (strain ATCC 700844 / DSMZ 13496 / JCM 10307 / IC-167) [Complete proteome] [HAMAP]
Taxonomic identifier397948 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Caldivirga

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 414414Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000124675

Sequences

Sequence LengthMass (Da)Tools
A8MB38 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: B44EBFC5880591E0

FASTA41443,924
        10         20         30         40         50         60 
MIVRINKSVA FGSVKAPRSK SWAIRLILLS AISDEETTIC SIPDSDDTEA ALRMIEVLGS 

        70         80         90        100        110        120 
KVIRQGNCIR VIPNLRQCGG YVNVGGSGTV MRLGVALASS CRNPVIIDGD ETLKRRPIRE 

       130        140        150        160        170        180 
LLESLRSLGV NVNGDSLPVA INGPVKGNYV EIRGDLTSQY ISGLIMLGLV SGITIRVIGD 

       190        200        210        220        230        240 
LVSRQYVDLT RRIIEESGCS VGVSNDVITV NECIPRISLS NVPGDYALSG FYTALALATG 

       250        260        270        280        290        300 
GLVTVTGLPK PLGYGDDSLV NIFSNAGARS VFSNGDWSVE GGGELRGIVV DLKDSPDLAP 

       310        320        330        340        350        360 
VVASIAPFAS GETVITGVRH LAFKESNRLE TISDSLRAFG VNVNHGDDSL RISGSITHGA 

       370        380        390        400        410 
LIKCPNDHRI AMMSGVVAAG SNGESIIHNA ECVNKSNRLF WRDLVKLGVK LTIN

« Hide

References

[1]"Complete sequence of Caldivirga maquilingensis IC-167."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ivanova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M., Saltikov C., House C.H., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700844 / DSMZ 13496 / JCM 10307 / IC-167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000852 Genomic DNA. Translation: ABW02667.1.
RefSeqYP_001541657.1. NC_009954.1.

3D structure databases

ProteinModelPortalA8MB38.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8MB38.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5709596.
GenomeReviewsGene locus Cmaq_1850 in contig CP000852_GR.
KEGGcma:Cmaq_1850.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646626.
OMAFADHRIA.

Enzyme and pathway databases

BioCycCMAQ397948:CMAQ_1850-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. False negative.
PS00885. EPSP_SYNTHASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_CALMQ
AccessionPrimary (citable) accession number: A8MB38
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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