A8M4B8 (GLMM_SALAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Sare_4252

Organism

Salinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP]

Taxonomic identifier

391037 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	451 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 451	451	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000343595
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A8M4B8 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: B8CA8636A0745EDD	FASTA	451	46,358
	10 20 30 40 50 60 MGRLFGTDGV RGRANADLTP ELALAVAVAA AHTLAEADRS HPPLAVVGRD TRASGEMLEA 70 80 90 100 110 120 AVVAGLTSAG ANVVRVGVLP TPAVAFLTAE AKADFGVMLS ASHNPMPDNG IKLFAAGGHK 130 140 150 160 170 180 LPDEIEMKIE AAIEANATTA WERPVGAGVG RVHDLLDGAD HYVQHLVGTV PHRLDGIKVV 190 200 210 220 230 240 VDCANGAAAE VAPAAYREAG AEVVEIHAKP DGLNINDECG SNHLAALQQA VVEHGAQLGI 250 260 270 280 290 300 AHDGDADRCV AVSADGDEVD GDQVMAILAL AMRQAGTLTA DTLVATVMSN LGLRIAMSRE 310 320 330 340 350 360 GIRLVETKVG DRYVLEELRA SGLALGGEQS GHIVMPAHAT TGDGVLTGLH LMSRLAATGK 370 380 390 400 410 420 SLAELAAVVT PLPQVLINVP VGDRTVGAVA PAVRAEVERA EVELGDAGRV LLRPSGTEPL 430 440 450 VRVMVEASTE TLARQVAERI ADQVRTASPV G

References

[1]

"Complete sequence of Salinispora arenicola CNS-205." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CNS-205.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000850 Genomic DNA. Translation: ABW00034.1.
RefSeq	YP_001539024.1. NC_009953.1.
3D structure databases
ProteinModelPortal	A8M4B8.
ModBase	Search...
Protein-protein interaction databases
STRING	A8M4B8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5704384.
GenomeReviews	Gene locus Sare_4252 in contig CP000850_GR.
KEGG	saq:Sare_4252.
PATRIC	23437087. VBISalAre38676_4292.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14318.
Enzyme and pathway databases
BioCyc	SARE391037:SARE_4252-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_SALAI

Accession

Primary (citable) accession number: A8M4B8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	December 4, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program