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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Salinispora arenicola (strain CNS-205)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei137 – 1371UniRule annotation
Active sitei574 – 5741UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSARE391037:GH66-841-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Sare_0828Imported
OrganismiSalinispora arenicola (strain CNS-205)Imported
Taxonomic identifieri391037 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
ProteomesiUP000001153 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi391037.Sare_0828.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8M2X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDQHDHDGP DAALRADIRR LGTLLGQTLA RQEGRPLLDL VEDIRAQVRT
60 70 80 90 100
DAPAAAQRLA GLDVATGTRL ARAFSTYFHL ANITEQVHRA RDLRRRRAIQ
110 120 130 140 150
GGWLDQAAKM IAERGVPAEE IAAAARRLAI RPVFTAHPTE AARRSILSKL
160 170 180 190 200
RAIADELDTE TTNAVLYGAS DEGPANRRLA ELLDLMWQTD ELRLDRPDPT
210 220 230 240 250
DEARNAIYYL RDLYAEAAPQ VLDDLADTLR TLGVETSPTA RPLTFGTWIG
260 270 280 290 300
GDRDGNPFVT PTVTREVLAI QHEHGLAATE RAMDQLINEV SVSRRLRGVS
310 320 330 340 350
LDLSASLATD LDALPEVAPR FRRVNAEEPY RLKARCVKAK LANTRQRLRQ
360 370 380 390 400
GTAHVPGRDY RGSGELIADL ELLRASLARN SGQLTAVGRL ASTIRTVSAF
410 420 430 440 450
GLHLATMDVR EHAEKHHEVL TQLFGAVGEV SDYPALSRLE RTKLLADELT
460 470 480 490 500
GRRPLSTVDT PLTESARRTF DVFGTIREAQ DRFGTEVIES YIISMTLGVD
510 520 530 540 550
DVLAAVVLAR EAGLVDVHSS RARIGFVPLL ETPAELNAGG DLLDELLSLP
560 570 580 590 600
AYRALVAARG DVQEVMLGYS DSNKEAGITT SQWSIHRAQR ALRDVAARHG
610 620 630 640 650
VHLRLFHGRG GTVGRGGGPT HDAILAQPYG TLDGEIKVTE QGEVISDKYT
660 670 680 690 700
LPALARENLE LTVAAVLQST LLHTAPRQPA EMLERWDATM DVVSAAAYRS
710 720 730 740 750
YRDLVEDPDL PAYFWASTPT ELLGALNIGS RPAKRPNTGA GLAGLRAIPW
760 770 780 790 800
VFGWTQTRQI VPGWFGVGSG LAAARAAGHA DVLAEMHRSW HFFRTFLSNV
810 820 830 840 850
EMMLTKTDLA IARRYVETLV PKKLHPIFHK IEQEYELTRR EVLAVTVTPD
860 870 880 890 900
LLENAPVLQR TLAVRDTYLE PLHHLQVALL RQYRESGAPG RAVATAPGGR
910 920
RAPSDGTALE RALLTTVNGI AAGMRNTG
Length:928
Mass (Da):101,703
Last modified:December 3, 2007 - v1
Checksum:i3B66B2CEC16AC357
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000850 Genomic DNA. Translation: ABV96746.1.
RefSeqiYP_001535737.1. NC_009953.1.

Genome annotation databases

EnsemblBacteriaiABV96746; ABV96746; Sare_0828.
KEGGisaq:Sare_0828.
PATRICi23430119. VBISalAre38676_0845.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000850 Genomic DNA. Translation: ABV96746.1.
RefSeqiYP_001535737.1. NC_009953.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391037.Sare_0828.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABV96746; ABV96746; Sare_0828.
KEGGisaq:Sare_0828.
PATRICi23430119. VBISalAre38676_0845.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciSARE391037:GH66-841-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CNS-205Imported.

Entry informationi

Entry nameiA8M2X8_SALAI
AccessioniPrimary (citable) accession number: A8M2X8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 3, 2007
Last sequence update: December 3, 2007
Last modified: March 31, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.