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A8M2W8 (FENR_SALAI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:Sare_0817
OrganismSalinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP]
Taxonomic identifier391037 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 322322Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364932

Sites

Binding site141FAD By similarity
Binding site331FAD By similarity
Binding site411FAD By similarity
Binding site461FAD By similarity
Binding site861FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1201FAD; via amide nitrogen By similarity
Binding site2781FAD By similarity
Binding site3191FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A8M2W8 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 935545754FFF5430

FASTA32233,598
        10         20         30         40         50         60 
MREIDVAVIG AGPSGLFAAY YAGFRGLSVA VVDALPEPGG QVTAMYPEKL IHDVAGFPAI 

        70         80         90        100        110        120 
RGRDLIANLV AQAAPFDPRY LLGTRAEKLT YVDGRPVLGL AGGEQLACGA VVITGGLGSF 

       130        140        150        160        170        180 
TPRPLPVAER FLGTGIVYFV PQPADLTNRD VLIVGGGDSA FDWASTLQPL ARSVTLVHRR 

       190        200        210        220        230        240 
ERFRAHAATV ARVRALPVRI VVNAEVTRLH GGGTVTGAEI TVRGGAAELL PVDTVVAALG 

       250        260        270        280        290        300 
FTADLGPLTE WGLRLDRRHI VVDSTMATNL PRVFAAGDIT EYPGKVRLIA TGFGEAATAV 

       310        320 
NNAAVVIDPA AHLFPGHSSD GS

« Hide

References

[1]"Complete sequence of Salinispora arenicola CNS-205."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. expand/collapse author list , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CNS-205.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000850 Genomic DNA. Translation: ABV96736.1.
RefSeqYP_001535727.1. NC_009953.1.

3D structure databases

ProteinModelPortalA8M2W8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8M2W8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5704121.
GenomeReviewsGene locus Sare_0817 in contig CP000850_GR.
KEGGsaq:Sare_0817.
PATRIC23430097. VBISalAre38676_0834.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK947807.

Enzyme and pathway databases

BioCycSARE391037:SARE_0817-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_SALAI
AccessionPrimary (citable) accession number: A8M2W8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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