A8LZJ2 (A8LZJ2_SALAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Porphobilinogen synthase EMBL ABV96358.1
EC=4.2.1.24 EMBL ABV96358.1

Gene names

Ordered Locus Names:

Sare_0429

Organism

Salinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP] EMBL ABV96358.1

Taxonomic identifier

391037 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5
Molecular function	Lyase EMBL ABV96358.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	197	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	249	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	234	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	207	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	218	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	275	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	314	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	A8LZJ2 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 52B3219CD02052E4	FASTA	327	34,838
	10 20 30 40 50 60 MPYPEIRPRR LRRSTALRRL VAETRVDPAE LVVPLFVKEG LTEPRAVASL PGVLQHTRES 70 80 90 100 110 120 LRKAAVAAVQ AGVGGIMLFG VPATRDERGS GGADPNGILN AAIRDVVSEV GDATVVMSDL 130 140 150 160 170 180 CLDEFTSHGH CGLLTPDGSV ANDATLAAYA EMAVAQAEAG VHVVGPSGMM DGQVGAVRQA 190 200 210 220 230 240 LDAAGHRDVT ILAYTAKYAS AFYGPFRDAV ESTLDGDRRT YQQDPANLRE SLREVALDVA 250 260 270 280 290 300 EGADIVMVKP ALPYLDVVAA VRAAVDVPVA AYQVSGEYAM VEAAAANGWI DRERVMVETL 310 320 TSIRRAGAQI ILTYWAVEAA QLLRERY

References

[1]

"Complete sequence of Salinispora arenicola CNS-205." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CNS-205.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000850 Genomic DNA. Translation: ABV96358.1.
RefSeq	YP_001535349.1. NC_009953.1.
3D structure databases
ProteinModelPortal	A8LZJ2.
SMR	A8LZJ2. Positions 6-324.
ModBase	Search...
Protein-protein interaction databases
STRING	A8LZJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5708406.
GenomeReviews	Gene locus Sare_0429 in contig CP000850_GR.
KEGG	saq:Sare_0429.
PATRIC	23429293. VBISalAre38676_0436.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285270.
OMA	ACGSESM.
ProtClustDB	PRK09283.
Enzyme and pathway databases
BioCyc	SARE391037:SARE_0429-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8LZJ2_SALAI

Accession

Primary (citable) accession number: A8LZJ2

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)