A8LYR0 (A8LYR0_SALAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006
Ordered Locus Names:	Sare_1888

Organism

Salinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP] EMBL ABV97773.1

Taxonomic identifier

391037 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	487 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL ABV97773.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8LYR0 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 79A94F19855F26EB	FASTA	487	52,095
	10 20 30 40 50 60 MGGVDDKSLT ENSAATNRTS LWGARFAGGP AEALARLSVS VQFDWRLAPY DIAGSRAHAR 70 80 90 100 110 120 VLAGAGLLDP EELGQILAAL DDLEAACAAG TFRPTVDDED VHTALERGLL ERLGRLGGKL 130 140 150 160 170 180 RAGRSRNDQV ATDLRLYLRD HARGVAARLV ELAEALVDQA GRHVETATPG MTHLQPAQPV 190 200 210 220 230 240 TFGHWLLAHV QPLLRDLQRL RDWDHRTAVS PLGAGALAGS GLPLDPVAVA RELGFRTSFA 250 260 270 280 290 300 NSMDAVADRD FVAEFLFTTA LIGVHLSRLG EEVVLWTSPE FGWVELDDAF ATGSSIMPQK 310 320 330 340 350 360 KNADIAELAR GKSGRLVGGL VSVLTMLKGL PMAYDRDMQE DKEPAFDAVD TLELLLPALA 370 380 390 400 410 420 GMISTMTVRV DRLVAAAPEG FSLATEVADW LVRRSVPFRE AHEITGRLVA LCVARGCALD 430 440 450 460 470 480 EVSDADLAAV SEHLDPAVRD VLSVRSALAA RTTPGSTGPG PVTDQLATAS DQLTGWREWA AEQVVPR

References

[1]

"Complete sequence of Salinispora arenicola CNS-205." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CNS-205.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000850 Genomic DNA. Translation: ABV97773.1.
RefSeq	YP_001536764.1. NC_009953.1.
3D structure databases
ProteinModelPortal	A8LYR0.
ModBase	Search...
Protein-protein interaction databases
STRING	A8LYR0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5704190.
GenomeReviews	Gene locus Sare_1888 in contig CP000850_GR.
KEGG	saq:Sare_1888.
PATRIC	23432292. VBISalAre38676_1916.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG539632.
OMA	MPGRTHL.
ProtClustDB	PRK00855.
Enzyme and pathway databases
BioCyc	SARE391037:SARE_1888-MONOMER.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8LYR0_SALAI

Accession

Primary (citable) accession number: A8LYR0

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)