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A8LY47 (A8LY47_SALAI) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281

EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281
Ordered Locus Names:Sare_1879
OrganismSalinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP] EMBL ABV97764.1
Taxonomic identifier391037 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
A8LY47 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 814156CB3FC897C2

FASTA35539,399
        10         20         30         40         50         60 
MTYRNDPYDP KQVALLDPAA LAEAVATAET AFAAATNPDA LTALRPAHLG DRAPASLARR 

        70         80         90        100        110        120 
EIGALPPAAK ADAGKRVNEA RRAIETAYAA RAEVLEREQA ERMLVEERVD VTLPYDRRPS 

       130        140        150        160        170        180 
GARHPVSTLM EQITDFFVGM GYEVAEGPEV ELEWTNFDAL NIPPDHPARG LMDTFHVAPE 

       190        200        210        220        230        240 
SSGLVLRTHT SPVQARTMLT RTPPIYVICP GRVYRTDELD ATHAPVFHQV EGLVVDRGIT 

       250        260        270        280        290        300 
MAHLRGTLDH FARAMFGPEA RTRFRPHYFP FTEPSAEFDV WFPEHRKGAR WVEWGGCGMV 

       310        320        330        340        350 
NPRVLRACGI DPEIYSGFAF GMGIDRTVMF RHGVGDMRDL VEGDVRFTRA FGYGA 

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References

[1]"Complete sequence of Salinispora arenicola CNS-205."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. expand/collapse author list , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CNS-205.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000850 Genomic DNA. Translation: ABV97764.1.
RefSeqYP_001536755.1. NC_009953.1.

3D structure databases

ProteinModelPortalA8LY47.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LY47.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5704323.
GenomeReviewsGene locus Sare_1879 in contig CP000850_GR.
KEGGsaq:Sare_1879.
PATRIC23432274. VBISalAre38676_1907.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284353.
OMAFRASYFP.
ProtClustDBPRK00488.

Enzyme and pathway databases

BioCycSARE391037:SARE_1879-MONOMER.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8LY47_SALAI
AccessionPrimary (citable) accession number: A8LY47
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)