A8LX39 (A8LX39_SALAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
Ordered Locus Names:	Sare_3397

Organism

Salinispora arenicola (strain CNS-205) [Complete proteome] [HAMAP] EMBL ABV99199.1

Taxonomic identifier

391037 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134
Molecular function	Decarboxylase HAMAP MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8LX39 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: B83CE315CFA5A7AA	FASTA	267	28,337
	10 20 30 40 50 60 MLDEILAGVR EDVARRQEQV PLERIRELAA AAPRPLDAYA SLRKPGVAVI AEVKRSSPSK 70 80 90 100 110 120 GRLAEIADPA DLAGDYAAGG ARAISVLTEG RWFGGSLDDL AAVRAAVDVP VLRKDFVVSS 130 140 150 160 170 180 YQVHEARAHG ADLVLLIVAA LEQKVLVGLL ERIESLGMTA LVEVHDEEEA DRALEAGARV 190 200 210 220 230 240 IGVNARDLRT LDVDRSVFER IAPGLPSTVV KIAESGVRGP HDLIRYASAG ADAVLVGEGL 250 260 VTQKSPREAV AELVNAGNHP ATPRPVR

References

[1]

"Complete sequence of Salinispora arenicola CNS-205." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Jensen P.R., Moore B.S., Penn K. , Jenkins C., Udwary D., Xiang L., Gontang E., Richardson P. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CNS-205.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000850 Genomic DNA. Translation: ABV99199.1.
RefSeq	YP_001538190.1. NC_009953.1.
3D structure databases
ProteinModelPortal	A8LX39.
ModBase	Search...
Protein-protein interaction databases
STRING	A8LX39.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5703503.
GenomeReviews	Gene locus Sare_3397 in contig CP000850_GR.
KEGG	saq:Sare_3397.
PATRIC	23435329. VBISalAre38676_3425.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG540956.
OMA	VESLGMT.
ProtClustDB	CLSK969551.
Enzyme and pathway databases
BioCyc	SARE391037:SARE_3397-MONOMER.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree] MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8LX39_SALAI

Accession

Primary (citable) accession number: A8LX39

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)