A8LRS5 (URED_DINSH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD

Gene names

Name:	ureD
Ordered Locus Names:	Dshi_2370

Organism

Dinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]

Taxonomic identifier

398580 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length	281 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 281	281	Urease accessory protein UreD HAMAP MF_01384		PRO_0000340451

Sequences

	Sequence		Length	Mass (Da)
	A8LRS5 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 0888B3B17FB355AD	FASTA	281	30,235
	10 20 30 40 50 60 MLNTLEPQPC ETDALSPRLQ RSTGSARVVM RRKADGTTAL ADLAQQGCAK AMLPRVHAPV 70 80 90 100 110 120 PEVVFLNTAG GVTGGDSLSY RLDLEAGAQA TGATQTAERT YRSSAGTGEM RVHLTLGSGA 130 140 150 160 170 180 RLDWLPQETI LFDGSATRRC TEVEMAADAT LLWCETLVFG RAAMGEALSR FAFRDDRQVR 190 200 210 220 230 240 RDGKLVLWEP LTLDATHLAP RACLGGARAI ATVAFLAPDA EAARDTVRRL APEGVDWAVS 250 260 270 280 AWDGKLVLRA FAPDAQPLKH ALAQVLHVLR EGASLPRVWQ L

References

[1]

"The complete genome sequence of the algal symbiont Dinoroseobacter shibae: a hitchhiker's guide to life in the sea." Wagner-Dobler I., Ballhausen B., Berger M., Brinkhoff T., Buchholz I., Bunk B., Cypionka H., Daniel R., Drepper T., Gerdts G., Hahnke S., Han C., Jahn D., Kalhoefer D., Kiss H., Klenk H.P., Kyrpides N., Liebl W. , Liesegang H., Meincke L., Pati A., Petersen J., Piekarski T., Pommerenke C., Pradella S., Pukall R., Rabus R., Stackebrandt E., Thole S., Thompson L., Tielen P., Tomasch J., von Jan M., Wanphrut N., Wichels A., Zech H., Simon M. ISME J. 4:61-77(2010) [PubMed: 19741735] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DFL 12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000830 Genomic DNA. Translation: ABV94106.1.
RefSeq	YP_001533707.1. NC_009952.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A8LRS5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5714025.
GenomeReviews	Gene locus Dshi_2370 in contig CP000830_GR.
KEGG	dsh:Dshi_2370.
PATRIC	21817463. VBIDinShi9476_2467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK940836.
Enzyme and pathway databases
BioCyc	DSHI398580:DSHI_2370-MONOMER.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED_DINSH

Accession

Primary (citable) accession number: A8LRS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	December 4, 2007
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program