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A8LP88 (A8LP88_DINSH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186 EMBL ABV95153.1
Ordered Locus Names:Dshi_3420
OrganismDinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]
Taxonomic identifier398580 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length519 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186 SAAS SAAS018483

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186 SAAS SAAS018483

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186 SAAS SAAS018483

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186 RuleBase RU003733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding434 – 4385ATP By similarity HAMAP MF_00186

Sites

Binding site341Substrate By similarity HAMAP MF_00186
Binding site381ATP By similarity HAMAP MF_00186
Binding site1041Substrate By similarity HAMAP MF_00186
Binding site1561Substrate By similarity HAMAP MF_00186
Binding site2651Substrate By similarity HAMAP MF_00186
Binding site2871ATP By similarity HAMAP MF_00186
Binding site3301ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
A8LP88 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 82147EECDCA22A4F

FASTA51956,261
        10         20         30         40         50         60 
MDRQRGQFLL NLRALKPRPG EGTVRHVLAI DQGTTSSRAI VFDADMNIVS IAQEEFAQHY 

        70         80         90        100        110        120 
PDSGWVEHDP EDLWDTVLRT CRNVLERTGL AATDLAGIGI TNQRETTVVW DKSTGKPIHN 

       130        140        150        160        170        180 
AIVWQDRRTA PFCAELRKAG HDALITAQTG LLADPYFSGT KLKYILDTVE GARDRAKAGE 

       190        200        210        220        230        240 
LLFGTVDSFL IWRLTNGAAH VTDATNAART MLYDIHKGAW SAEICTLFDI PLGMLPQVHD 

       250        260        270        280        290        300 
CDAEFGTCTP EHLGGAVPIL GVAGDQQAAT IGQACFEPGM LKSTYGTGCF ALLNTGEAPV 

       310        320        330        340        350        360 
TSTNRLLTTI AYQLDGKPTY ALEGSIFVAG AVVQWLRDGL KLIANASETQ PLAEAADPHD 

       370        380        390        400        410        420 
PVILVPAFTG LGAPYWNAEC RGAVFGLSRG SGPEEFARAA LESVGYQTRD LLEAMHKDWS 

       430        440        450        460        470        480 
DAREGQPTLR VDGGMTASDW TMQFLADIID APVDRPKITE TTALGVAWLA GQKAGLYPDR 

       490        500        510 
AGFAANWALD QRFEPKMDAT TRDTKYAAWK RAVAAVQQA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000830 Genomic DNA. Translation: ABV95153.1.
RefSeqYP_001534754.1. NC_009952.1.

3D structure databases

ProteinModelPortalA8LP88.
SMRA8LP88. Positions 26-513.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LP88.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5712478.
GenomeReviewsGene locus Dshi_3420 in contig CP000830_GR.
KEGGdsh:Dshi_3420.
PATRIC21819649. VBIDinShi9476_3553.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG511469.
OMACYQTRDL.
ProtClustDBCLSK956447.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8LP88_DINSH
AccessionPrimary (citable) accession number: A8LP88
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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