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Reviewed, UniProtKB/Swiss-Prot A8LP53 (XYLA_DINSH)

Last modified February 9, 2010. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: Dshi_1996
OrganismDinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]
Taxonomic identifier398580 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

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Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Xylose isomerase HAMAP MF_00455
PRO_1000081028

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
A8LP53-1 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 5307085BE466F244

FASTA43448,493
        10         20         30         40         50         60 
MSDFFAGIPA VTYEGPEARS DFAFRHYNPD EMVMGKRMED QLRFAVAWWH SFAWEGGDPF 

        70         80         90        100        110        120 
GGPTFQRPWF GDTLDHARAK ADAAFEMFRI LNVPFYCFHD ADIRPEGASF AETTANLEAM 

       130        140        150        160        170        180 
VDYLGQKQEA SGKRLLWGTA NLFSHRRYMA GAATNPDPDV FAYAAATIKT CMDATHKLGG 

       190        200        210        220        230        240 
ANYVLWGGRE GYETLLNTDL GREREQAGRM LQMVVDYKHK IGFEGTILLE PKPQEPTKHQ 

       250        260        270        280        290        300 
YDYDVATVFS FLSEFGLQDE VKMNIEQGHA ILAGHSFEHE LALAREFGIL GSIDMNRNDY 

       310        320        330        340        350        360 
QSGWDTDQFP NNIPEVALAY YEILRAGGFD TGGTNFDSKL RRQSLDPADL IAAHVAAMDV 

       370        380        390        400        410        420 
CAAGLKAAAR MLEDGELEQR REDRYAGWRA PSAEAMLNGG KLEDCFAHVM ETGLDPQPVS 

       430 
GGQERLEALV ARYL

« Hide

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References

[1]"Complete sequence of chromosome of Dinoroseobacter shibae DFL 12."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Kim E., Richardson P.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000830 Genomic DNA. Translation: ABV93735.1.
RefSeqYP_001533336.1.

3D structure databases

SMRA8LP53. Positions 2-434.
ModBaseSearch...

Genome annotation databases

GeneID5712991.
GenomeReviewsGene locus Dshi_1996 in contig CP000830_GR.
KEGGdsh:Dshi_1996.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_DINSH
AccessionPrimary (citable) accession number: A8LP53
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: February 9, 2010
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents