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A8LN46 (ATPA1_DINSH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit alpha 1
EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit alpha 1
F-ATPase subunit alpha 1
Gene names
Name:atpA1
Ordered Locus Names:Dshi_0442
OrganismDinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]
Taxonomic identifier398580 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length509 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. HAMAP MF_01346

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_01346

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a1, b1, b'1 and c(9-12) By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_01346.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 509509ATP synthase subunit alpha 1 HAMAP MF_01346
PRO_0000339031

Regions

Nucleotide binding172 – 1798ATP By similarity

Sites

Site3631Required for activity By similarity

Sequences

Sequence LengthMass (Da)Tools
A8LN46 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 4011DD2E82E5C246

FASTA50953,220
        10         20         30         40         50         60 
MRHDTDPRPS TADLIDAVLD APPPRPEVSE VGRVAELGDG IAIVTGLARA LADEVLDFAS 

        70         80         90        100        110        120 
GVSGIVFDLE PGRLGVVLLG PSQNVAMGED VRRTGRVVSV PVGPATLGRV VDALGRPRDE 

       130        140        150        160        170        180 
RDPVTDSPLA PVEAEAPDIL SRTPVSRPLA TGLKAVDAAV PVGLGQRQLI IGDRQTGKTS 

       190        200        210        220        230        240 
IAVDTILNQK DTGVICIYCA IGQRGDAVAK VIGALQGGEM LGQTVVIAAG DEDAPGLAYI 

       250        260        270        280        290        300 
APYAAMSVAE SFAAQGRDVL VVLDDLTHHA RTYRELSLLL RRPPGREAFP GDIFYVHARL 

       310        320        330        340        350        360 
LERAGQFGEG AGSITALPVV ETQAENLSAY IPTNLISITD GQIYLSPKLV RTNQFPAVDL 

       370        380        390        400        410        420 
GVSVSRVGGK AQARAFRAVG GNLRVTLSQF EELEEFARFG TRLDEDTRAR LARGGAVRNA 

       430        440        450        460        470        480 
LRQAERDPMA AHEQLAVLVA AMEGLLDGMD EAAAGAAMQA IRAAIRAADG GLPEIIAGDE 

       490        500 
KLTEDARGHI LATARAALAQ TGRGDGADA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000830 Genomic DNA. Translation: ABV92190.1.
RefSeqYP_001531791.1. NC_009952.1.

3D structure databases

ProteinModelPortalA8LN46.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LN46.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5711358.
GenomeReviewsGene locus Dshi_0442 in contig CP000830_GR.
KEGGdsh:Dshi_0442.
PATRIC21813363. VBIDinShi9476_0447.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG565875.
OMANVLCVYC.
ProtClustDBCLSK958227.

Enzyme and pathway databases

BioCycDSHI398580:DSHI_0442-MONOMER.

Family and domain databases

HAMAPMF_01346. ATP_synth_alpha_bact.
[Tree]
InterProIPR005294. ATPase_F1-cplx_asu.
IPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR023366. ATPase_F1/A1-cplx_a_su_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
[Graphical view]
Gene3DG3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
KOK02111.
PANTHERPTHR15184:SF3. ATPase_F1_a. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMsTIGR00962. AtpA. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPA1_DINSH
AccessionPrimary (citable) accession number: A8LN46
Entry history
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: December 4, 2007
Last modified: January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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