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A8LMV2 (A8LMV2_DINSH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase 1 HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase 1 HAMAP MF_00315
Gene names
Name:dxs1 HAMAP MF_00315 EMBL ABV95027.1
Ordered Locus Names:Dshi_3294
OrganismDinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]
Taxonomic identifier398580 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length643 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
A8LMV2 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: AF826F469D3FA38B

FASTA64368,215
        10         20         30         40         50         60 
MSDRPHTPVL DRVKTPDDMK GLSDRELVAL ARDLRAETIS AVSVTGGHLG AGLGVVELTV 

        70         80         90        100        110        120 
ALHAVFDAPR DRIIWDVSHQ CYPHKILTGR RDRIRTLRMK DGLSGFTKRS ESPYDPFGAA 

       130        140        150        160        170        180 
HSSTSISAAL GFAVARDLGG APEHGIGDAI AVIGDGAISA GMAFEALNNA GHLKKRLIVI 

       190        200        210        220        230        240 
LNDNEMSIAP PTGAMSSYLN RLYAGAPFQE FKAAAKGAVS LLPPPFQEGA KRAKDILKHM 

       250        260        270        280        290        300 
TIGGTLFEEL GFSYVGPIDG HDMEQLLSVL RTVKARADGP ILIHAITKKG KGYAPAEGAA 

       310        320        330        340        350        360 
DKGHATAKFD VVSGAQKKAP SNAPTYTNVF AETLIDEAER DSRIVAVTAA MPSGTGLDKF 

       370        380        390        400        410        420 
AKRFAARTFD VAIAEQHGVT FCAGLAAGGM KPFCTMYSTF LQRGYDQVVH DVALQNLPVR 

       430        440        450        460        470        480 
FAIDRAGLVG ADGATHAGAY DTAYLSNLPN MVVMAAADEA ELRHMVATAV AHDSGPIAFR 

       490        500        510        520        530        540 
FPRGEGVGVE LPERGVPLEI GKGRIIAEGS RVAILSFGTR LAEVREACEA LTARGITPTV 

       550        560        570        580        590        600 
ADARFAKPLD RDLILRLAAE HEALITIEEG AVGGFGSHVA QLLSEEGVFD TGLKFRSMVL 

       610        620        630        640 
PDTFIDQASP RDMYDIAGLN APDIEAKVLS VLGVAQIDRR AQS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000830 Genomic DNA. Translation: ABV95027.1.
RefSeqYP_001534628.1. NC_009952.1.

3D structure databases

ProteinModelPortalA8LMV2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LMV2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5712351.
GenomeReviewsGene locus Dshi_3294 in contig CP000830_GR.
KEGGdsh:Dshi_3294.
PATRIC21819391. VBIDinShi9476_3425.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG571647.
OMAKRDESAH.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8LMV2_DINSH
AccessionPrimary (citable) accession number: A8LMV2
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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