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A8LLG2

- EFTU_DINSH

UniProt

A8LLG2 - EFTU_DINSH

Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi76 – 805GTPUniRule annotation
    Nucleotide bindingi131 – 1344GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDSHI398580:GKEL-222-MONOMER.
    DSHI398580:GKEL-274-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tuf1UniRule annotation
    Ordered Locus Names:Dshi_0223
    AND
    Name:tuf2UniRule annotation
    Ordered Locus Names:Dshi_0274
    OrganismiDinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)
    Taxonomic identifieri398580 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeDinoroseobacter
    ProteomesiUP000006833: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 391391Elongation factor TuPRO_0000337373Add
    BLAST

    Proteomic databases

    PRIDEiA8LLG2.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi398580.Dshi_0274.

    Structurei

    3D structure databases

    ProteinModelPortaliA8LLG2.
    SMRiA8LLG2. Positions 2-390.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 201192tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni55 – 595G2By similarity
    Regioni76 – 794G3By similarity
    Regioni131 – 1344G4By similarity
    Regioni169 – 1713G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiISAPAAC.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8LLG2-1 [UniParc]FASTAAdd to Basket

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    MAKEKFERSK PHVNIGTIGH VDHGKTTLTA AITKQFGDFK AYDEIDGAPE    50
    EKARGITIST AHVEYETDAR HYAHVDCPGH ADYVKNMITG AAQMDGAILV 100
    VNAADGPMPQ TREHILLGRQ VGIPYMVVFM NKVDQVDDEE LLELVEMEIR 150
    ELLSSYEYPG DDIPIIAGSA LAALEGRDPE IGEQKIAELM KAVDDYIPTP 200
    ARAVDQPFLM PIEDVFSISG RGTVVTGRVE RGVINVGDEI EIVGIRDTKK 250
    TTCTGVEMFR KLLDRGEAGD NIGALLRGVD REGVERGQVL CKPGSVTPHT 300
    KFEAEAYILT KEEGGRHTPF FANYRPQFYF RTTDVTGTVT LPEGTEMVMP 350
    GDNLKFGVEL IAPIAMEDGL RFAIREGGRT VGAGVVSKII E 391
    Length:391
    Mass (Da):42,777
    Last modified:December 4, 2007 - v1
    Checksum:iB701ECE5949571A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000830 Genomic DNA. Translation: ABV91972.1.
    CP000830 Genomic DNA. Translation: ABV92023.1.
    RefSeqiWP_012176905.1. NC_009952.1.
    YP_001531573.1. NC_009952.1.
    YP_001531624.1. NC_009952.1.

    Genome annotation databases

    EnsemblBacteriaiABV91972; ABV91972; Dshi_0223.
    ABV92023; ABV92023; Dshi_0274.
    GeneIDi5711524.
    5712148.
    KEGGidsh:Dshi_0223.
    dsh:Dshi_0274.
    PATRICi21812891. VBIDinShi9476_0221.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000830 Genomic DNA. Translation: ABV91972.1 .
    CP000830 Genomic DNA. Translation: ABV92023.1 .
    RefSeqi WP_012176905.1. NC_009952.1.
    YP_001531573.1. NC_009952.1.
    YP_001531624.1. NC_009952.1.

    3D structure databases

    ProteinModelPortali A8LLG2.
    SMRi A8LLG2. Positions 2-390.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 398580.Dshi_0274.

    Proteomic databases

    PRIDEi A8LLG2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABV91972 ; ABV91972 ; Dshi_0223 .
    ABV92023 ; ABV92023 ; Dshi_0274 .
    GeneIDi 5711524.
    5712148.
    KEGGi dsh:Dshi_0223.
    dsh:Dshi_0274.
    PATRICi 21812891. VBIDinShi9476_0221.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ISAPAAC.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci DSHI398580:GKEL-222-MONOMER.
    DSHI398580:GKEL-274-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16493 / NCIMB 14021 / DFL 12.

    Entry informationi

    Entry nameiEFTU_DINSH
    AccessioniPrimary (citable) accession number: A8LLG2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3