A8LKY6 (A8LKY6_DINSH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:	aroB HAMAP MF_00110 EMBL ABV93350.1
Ordered Locus Names:	Dshi_1608

Organism

Dinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]

Taxonomic identifier

398580 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length	383 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL ABV93350.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8LKY6 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: DF5FB77CE845255C	FASTA	383	40,346
	10 20 30 40 50 60 MTMSAAPAPQ TVYVPLEDRA YDVVIGPGLL AQAGARISPF LPRPKVAIVS DETVAALHLA 70 80 90 100 110 120 TLQDSLATAG IDSTALILPA GEATKGWPEF SRTVDWLLAQ KIERRDLVIA FGGGVIGDLV 130 140 150 160 170 180 GFAAAVLRRG VGFIQIPTSL LAQVDSSVGG KTGINSVHGK NLIGAFHQPR LVLADTDVLG 190 200 210 220 230 240 TLTPRDFLAG YGEVVKYGLL GDADFFAWLE TEGPRLAAGD GSARVAAVRR SVEMKAEIVV 250 260 270 280 290 300 RDETEQGDRA LLNLGHTFCH ALEAATGYSD RLLHGEGVAI GCALAFDLSA RLGLCAQEDP 310 320 330 340 350 360 SRVRAHLQTM GMKRDLRDIA GDLPDAEALL NLMGQDKKVM DGTLRFILAR GIGQAFMTSE 370 380 VPSEAVLSVL RASASGMVSA PKA

References

[1]

"The complete genome sequence of the algal symbiont Dinoroseobacter shibae: a hitchhiker's guide to life in the sea." Wagner-Dobler I., Ballhausen B., Berger M., Brinkhoff T., Buchholz I., Bunk B., Cypionka H., Daniel R., Drepper T., Gerdts G., Hahnke S., Han C., Jahn D., Kalhoefer D., Kiss H., Klenk H.P., Kyrpides N., Liebl W. , Liesegang H., Meincke L., Pati A., Petersen J., Piekarski T., Pommerenke C., Pradella S., Pukall R., Rabus R., Stackebrandt E., Thole S., Thompson L., Tielen P., Tomasch J., von Jan M., Wanphrut N., Wichels A., Zech H., Simon M. ISME J. 4:61-77(2010) [PubMed: 19741735] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DFL 12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000830 Genomic DNA. Translation: ABV93350.1.
RefSeq	YP_001532951.1. NC_009952.1.
3D structure databases
ProteinModelPortal	A8LKY6.
ModBase	Search...
Protein-protein interaction databases
STRING	A8LKY6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5712752.
GenomeReviews	Gene locus Dshi_1608 in contig CP000830_GR.
KEGG	dsh:Dshi_1608.
PATRIC	21815839. VBIDinShi9476_1670.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG632303.
OMA	VMALEMS.
ProtClustDB	PRK00002.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
KO	K01735.
PANTHER	PTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8LKY6_DINSH

Accession

Primary (citable) accession number: A8LKY6

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)