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A8LHP4 (A8LHP4_DINSH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrA 1 HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase 1 HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401
Alternative name(s):
Peptide-methionine (S)-S-oxide reductase 1 HAMAP MF_01401
Gene names
Name:msrA2 EMBL ABV92841.1
Synonyms:msrA1 HAMAP MF_01401
Ordered Locus Names:Dshi_1099
OrganismDinoroseobacter shibae (strain DFL 12) [Complete proteome] [HAMAP]
Taxonomic identifier398580 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Dinoroseobacter

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401

Catalytic activity

L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site551 By similarity HAMAP MF_01401

Sequences

Sequence LengthMass (Da)Tools
A8LHP4 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 4B431C96A35D0FB0

FASTA22023,996
        10         20         30         40         50         60 
MFFMSRKKAE MVRAEDALPG RAAAIPTADT HFLSGRPLTL SVPEGMEVAM FGMGCFWGVE 

        70         80         90        100        110        120 
RMFWKLEGVW LTMVGYAGGF TQNPTYQEVC TGQTGHNEVV RVVYDPKVIS YETLLQVFWE 

       130        140        150        160        170        180 
GHDPTQGMRQ GNDVGTQYRS GIYTTTEAQA QAAQDSRAAY ADQLRKAGFG AITTEIVPAP 

       190        200        210        220 
SFYFAEDYHQ QYLAKNPNGY CGIGGTGVSC PIGTGIAQAG

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000830 Genomic DNA. Translation: ABV92841.1.
RefSeqYP_001532442.1. NC_009952.1.

3D structure databases

ProteinModelPortalA8LHP4.
SMRA8LHP4. Positions 8-197.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LHP4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5711067.
GenomeReviewsGene locus Dshi_1099 in contig CP000830_GR.
KEGGdsh:Dshi_1099.
PATRIC21814783. VBIDinShi9476_1145.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG748152.
OMASAIYCTS.
ProtClustDBCLSK940854.

Family and domain databases

HAMAPMF_01401. MsrA.
[Tree]
InterProIPR002569. Peptide_Met_Sox_Rdtase_MsrA.
[Graphical view]
Gene3DG3DSA:3.30.1060.10. MsrA. 1 hit.
KOK07304.
PfamPF01625. PMSR. 1 hit.
[Graphical view]
SUPFAMSSF55068. MsrA. 1 hit.
TIGRFAMsTIGR00401. MsrA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8LHP4_DINSH
AccessionPrimary (citable) accession number: A8LHP4
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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