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A8LE04 (A8LE04_FRASN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase 2 HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB2 HAMAP MF_00110
Ordered Locus Names:Franean1_1701
OrganismFrankia sp. (strain EAN1pec) [Complete proteome] [HAMAP] EMBL ABW11139.1
Taxonomic identifier298653 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ABW11139.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A8LE04 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 6B6081488E358636

FASTA37138,949
        10         20         30         40         50         60 
MCAMKVSDMV RIQVTPSGDR AYDVVLGEGA LCELPALAAG RTRVMVIHPR ALRATAAAVI 

        70         80         90        100        110        120 
AELRAGAGAG VETHAFEVPD GEEAKQLRVA GACWDALGRV GFTRDDLVVG LGGGTTTDLA 

       130        140        150        160        170        180 
GFAAAGWLRG VDVIQVPTTV LGMVDAAVGG KTGIDIEAGK NLVGAFHQPL AVLCDLSTLA 

       190        200        210        220        230        240 
SLPAVEVRAG LAEVVKAGFI ADPRILELLE ADPTGSARLP ELVERSIRVK AAVVSGDPRE 

       250        260        270        280        290        300 
AGRREILNYG HTLAHAIEKV ENFSWRHGAA VSVGMVFAAE LSRLVAGLDR VTADRHRELL 

       310        320        330        340        350        360 
RAIGLPVEYR GDRWPALLDA MRVDKKTRGR RLRFVVLEAL GRPRGFDDPE PGLLLAAYGS 

       370 
VAAGGVSATG N

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000820 Genomic DNA. Translation: ABW11139.1.
RefSeqYP_001506045.1. NC_009921.1.

3D structure databases

ProteinModelPortalA8LE04.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8LE04.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5670103.
GenomeReviewsGene locus Franean1_1701 in contig CP000820_GR.
KEGGfre:Franean1_1701.
PATRIC21936266. VBIFraSp51419_1746.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMALGQSDFT.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA8LE04_FRASN
AccessionPrimary (citable) accession number: A8LE04
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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