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A8L8W2

- RNPA_FRASN

UniProt

A8L8W2 - RNPA_FRASN

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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Frankia sp. (strain EAN1pec)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciFSP298653:GHPI-7376-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:Franean1_7340
OrganismiFrankia sp. (strain EAN1pec)
Taxonomic identifieri298653 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
ProteomesiUP000001313: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Ribonuclease P protein componentPRO_1000100362Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi298653.Franean1_7340.

Structurei

3D structure databases

ProteinModelPortaliA8L8W2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiNOG299111.
HOGENOMiHOG000266301.
KOiK03536.
OMAiMRARSEF.
OrthoDBiEOG6C01C6.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8L8W2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLPRGSRVRT RQEHALVGRS GRRVRAGSIV VHSVQTDVDG PPRAGFVVGR
60 70 80 90 100
RVGNAVVRNR VRRRLREQTR SRLSSLPPGT AVLIRALPDA AGSSSADLGR
110 120
SLDSAFRTVR SPRPQRSARS G
Length:121
Mass (Da):13,140
Last modified:December 4, 2007 - v1
Checksum:i54653FE082380002
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000820 Genomic DNA. Translation: ABW16659.1.
RefSeqiWP_020464713.1. NC_009921.1.
YP_001511565.1. NC_009921.1.

Genome annotation databases

EnsemblBacteriaiABW16659; ABW16659; Franean1_7340.
GeneIDi5675641.
KEGGifre:Franean1_7340.
PATRICi21948514. VBIFraSp51419_7848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000820 Genomic DNA. Translation: ABW16659.1 .
RefSeqi WP_020464713.1. NC_009921.1.
YP_001511565.1. NC_009921.1.

3D structure databases

ProteinModelPortali A8L8W2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 298653.Franean1_7340.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABW16659 ; ABW16659 ; Franean1_7340 .
GeneIDi 5675641.
KEGGi fre:Franean1_7340.
PATRICi 21948514. VBIFraSp51419_7848.

Phylogenomic databases

eggNOGi NOG299111.
HOGENOMi HOG000266301.
KOi K03536.
OMAi MRARSEF.
OrthoDBi EOG6C01C6.

Enzyme and pathway databases

BioCyci FSP298653:GHPI-7376-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EAN1pec.

Entry informationi

Entry nameiRNPA_FRASN
AccessioniPrimary (citable) accession number: A8L8W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: December 4, 2007
Last modified: October 1, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3