A8L6K2 (A8L6K2_FRASN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Diaminopimelate epimerase HAMAP MF_00197
Short name=DAP epimerase HAMAP MF_00197
EC=5.1.1.7 HAMAP MF_00197

Gene names

Name:	dapF HAMAP MF_00197
Ordered Locus Names:	Franean1_1230

Organism

Frankia sp. (strain EAN1pec) [Complete proteome] [HAMAP] EMBL ABW10684.1

Taxonomic identifier

298653 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197 SAAS SAAS018510
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197 SAAS SAAS018510
Subcellular location	Cytoplasm By similarity HAMAP MF_00197 SAAS SAAS018510.
Sequence similarities	Belongs to the diaminopimelate epimerase family. HAMAP MF_00197

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis HAMAP MF_00197 SAAS SAAS018510
Cellular component	Cytoplasm HAMAP MF_00197 SAAS SAAS018510
Molecular function	Isomerase HAMAP MF_00197 SAAS SAAS018510 EMBL ABW10684.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	90	1	By similarity HAMAP MF_00197
	Active site	224	1	By similarity HAMAP MF_00197

Sequences

	Sequence		Length	Mass (Da)
	A8L6K2 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 6A8B59B837D61F33	FASTA	307	31,222
	10 20 30 40 50 60 MSSPRPYDRG VRFVKGHGTG NDFLILPDAD GELDLSPELV RALCHRGTGI GADGVLRVVL 70 80 90 100 110 120 TAAEPAAGDS AAARWFMDYR NADGSIAEMC GNGIRVFARY LVDAGYAAPG RLVIATRAGL 130 140 150 160 170 180 RAVEVPAGGD VTVEMGPPEL AAGPVPVTVA GREFAAVPVS MGNPHAVCFA DDLDPAGLAR 190 200 210 220 230 240 LDLRAPAYPA AAFPEGVNVE VVVPAPDGVA MRVFERGVGE TASCGTGACA VAVAWAARNG 250 260 270 280 290 300 DGPPAEVEVD LPGGRLTVGW RESTVLLSGP AVLVSDGVLR PDWLRAAGGF GPAAPAGERR PSAVGAG

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000820 Genomic DNA. Translation: ABW10684.1.
RefSeq	YP_001505590.1. NC_009921.1.
3D structure databases
ProteinModelPortal	A8L6K2.
ModBase	Search...
Protein-protein interaction databases
STRING	A8L6K2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5669643.
GenomeReviews	Gene locus Franean1_1230 in contig CP000820_GR.
KEGG	fre:Franean1_1230.
PATRIC	21935322. VBIFraSp51419_1275.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG399442.
OMA	FMTGPAT.
ProtClustDB	PRK00450.
Family and domain databases
HAMAP	MF_00197. DAP_epimerase. [Tree]
InterPro	IPR018510. DAP_epimerase_AS. IPR001653. DAP_epimerase_DapF. [Graphical view]
KO	K01778.
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8L6K2_FRASN

Accession

Primary (citable) accession number: A8L6K2

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)