A8L2M1 (A8L2M1_FRASN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	Franean1_0958

Organism

Frankia sp. (strain EAN1pec) [Complete proteome] [HAMAP] EMBL ABW10414.1

Taxonomic identifier

298653 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 EMBL ABW10414.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8L2M1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 23AEB8B44AD9DABA	FASTA	459	46,988
	10 20 30 40 50 60 MQRGQDDPWS APVATGPVRA TVTVPGSKSG TNRALVLAAA ADGVSRLRGA LRSRDTVLMA 70 80 90 100 110 120 AALRELGATV TDEAAPGGAE PGRPGEPGAD QGAADIVVTG PVGAVRGTAA IDCGNAGTVA 130 140 150 160 170 180 RFTPALATLA RGDVRFDGDP RMRDRPLTPL LRALRELGAH IDGDRMPFTV RGTGAVSGGA 190 200 210 220 230 240 VTVDASDSSQ LVSGLLLAAA RFERGATVTH AGHRLPSGPY LDMTVADLRA AGVVVDVDDP 250 260 270 280 290 300 TADLLRAGGT PAASTRRWRV KPGGPRPLDR VIEPDLNSAA PFVAAAAVTG GEVTITGWPA 310 320 330 340 350 360 STEQPGRMLP DLLVAMGCRA ELVPEGLRVT GGGRITGIDV DLSDFGEAAP VLTGLAVLAD 370 380 390 400 410 420 SPSRLRGIAH LRLQETDRLA ALASELGRLG ARVTVTDDGL SIIPVPLRGA RLDPHADHRL 430 440 450 AMTYAVVGLA VPGVTVDDIA TTGKTVPDFA RMWTTMLAG

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000820 Genomic DNA. Translation: ABW10414.1.
RefSeq	YP_001505320.1. NC_009921.1.
3D structure databases
ProteinModelPortal	A8L2M1.
ModBase	Search...
Protein-protein interaction databases
STRING	A8L2M1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5669372.
GenomeReviews	Gene locus Franean1_0958 in contig CP000820_GR.
KEGG	fre:Franean1_0958.
PATRIC	21934746. VBIFraSp51419_0993.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646626.
OMA	HRMATAG.
ProtClustDB	PRK02427.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 3 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
PROSITE	PS00104. EPSP_SYNTHASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A8L2M1_FRASN

Accession

Primary (citable) accession number: A8L2M1

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)