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A8L1V5 (A8L1V5_FRASN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:Franean1_5257
OrganismFrankia sp. (strain EAN1pec) [Complete proteome] [HAMAP] EMBL ABW14615.1
Taxonomic identifier298653 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. SAAS SAAS011529 HAMAP MF_00456

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity HAMAP MF_00456 SAAS SAAS011529.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain275 – 35379PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A8L1V5 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 44774D605F9D9BAF

FASTA37138,398
        10         20         30         40         50         60 
MVRSFVTEAN RVVVKVGSSS LTTAAGGLDA DRVEALVAAV AGRAGSLVLV SSGAIAAGLA 

        70         80         90        100        110        120 
PLGLTRRPRD LATLQAAASV GQSSLVHCYA GAFGRAGHRV GQVLLTATDV IRRTHYRNAR 

       130        140        150        160        170        180 
TTLERLLALG VVPIVNENDA VATQEIRFGD NDRLAAIVSH LVSADLLVLL SDVDGVYESN 

       190        200        210        220        230        240 
PRLGPASMVR EVRSDADLDG LTARGTGAAG VGVGGMATKI DAARMAASGG VTTVVTSAAN 

       250        260        270        280        290        300 
AAAVLAGEEI GTVFHPTGPR RPSRLLWLAH ATAPEGRLHL DEGAVAAVVD RRASLLPAGV 

       310        320        330        340        350        360 
TKVEGDFSAG DPVDLVDPRG RPVARGLVEF DSVELPGMLG RSTMDLAAER GPSYEREVVH 

       370 
RDDLVLLLTR R

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000820 Genomic DNA. Translation: ABW14615.1.
RefSeqYP_001509521.1. NC_009921.1.

3D structure databases

ProteinModelPortalA8L1V5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA8L1V5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5673591.
GenomeReviewsGene locus Franean1_5257 in contig CP000820_GR.
KEGGfre:Franean1_5257.
PATRIC21943828. VBIFraSp51419_5520.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA8L1V5_FRASN
AccessionPrimary (citable) accession number: A8L1V5
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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