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A8KYR5

- PGK_FRASN

UniProt

A8KYR5 - PGK_FRASN

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Protein
Phosphoglycerate kinase
Gene
pgk, Franean1_2064
Organism
Frankia sp. (strain EAN1pec)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381Substrate By similarity
Binding sitei124 – 1241Substrate By similarity
Binding sitei161 – 1611Substrate By similarity
Binding sitei211 – 2111ATP By similarity
Binding sitei299 – 2991ATP; via carbonyl oxygen By similarity
Binding sitei330 – 3301ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi356 – 3594ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFSP298653:GHPI-2085-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Franean1_2064
OrganismiFrankia sp. (strain EAN1pec)
Taxonomic identifieri298653 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
ProteomesiUP000001313: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinaseUniRule annotation
PRO_1000192832Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi298653.Franean1_2064.

Structurei

3D structure databases

ProteinModelPortaliA8KYR5.
SMRiA8KYR5. Positions 1-399.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 213Substrate binding By similarity
Regioni61 – 644Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8KYR5-1 [UniParc]FASTAAdd to Basket

« Hide

MRTIDDLQVT GHRVLVRSDL NVPLDHSKGA PRITDDGRVR ASVPTIQALL    50
DRNAKVIVCS HLGRPKGAPE EKYSLAPVAE RLAELLGIPV AFAGDGGGDI 100
AGDRAREVVG QLAEGQVALL ENLRFHPGET SKDTVARATF ADELSALAEF 150
YVGDAFGAVH RAHASVSEVP KRLPHAAGRL VLTELEVLRA LTAAPARPYA 200
VVLGGSKVSD KLGVIRALLP KVDALLVGGG MCFTFLAALG HPVGASLLES 250
EMIDTCKDLL AEAGDRLVLP TDVVVADRFA ADAETAVVAA DAIPDGWLGL 300
DIGPASTAAF ARVVAGAATI FWNGPMGVFE FAPFAEGTRG VAEAVASGGG 350
FSVVGGGDSA AAVRILGIPE DDFSHISTGG GASLEYLEGK TLPGLAALDV 400
Length:400
Mass (Da):41,182
Last modified:December 4, 2007 - v1
Checksum:i85ED41D629E09A3D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000820 Genomic DNA. Translation: ABW11501.1.
RefSeqiWP_020459668.1. NC_009921.1.
YP_001506407.1. NC_009921.1.

Genome annotation databases

EnsemblBacteriaiABW11501; ABW11501; Franean1_2064.
GeneIDi5670465.
KEGGifre:Franean1_2064.
PATRICi21937066. VBIFraSp51419_2142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000820 Genomic DNA. Translation: ABW11501.1 .
RefSeqi WP_020459668.1. NC_009921.1.
YP_001506407.1. NC_009921.1.

3D structure databases

ProteinModelPortali A8KYR5.
SMRi A8KYR5. Positions 1-399.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 298653.Franean1_2064.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABW11501 ; ABW11501 ; Franean1_2064 .
GeneIDi 5670465.
KEGGi fre:Franean1_2064.
PATRICi 21937066. VBIFraSp51419_2142.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci FSP298653:GHPI-2085-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EAN1pec.

Entry informationi

Entry nameiPGK_FRASN
AccessioniPrimary (citable) accession number: A8KYR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 4, 2007
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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