A8KWE6 (A8KWE6_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative UDP-3-0-acyl N-acetylglucosamine deacetylase EMBL EDO94976.1

Gene names

ORF Names:

BURPSPAST_AB0141 EMBL EDO94976.1

Organism

Burkholderia pseudomallei Pasteur 52237 EMBL EDO94976.1

Taxonomic identifier

331978 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8KWE6 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: F5CDAEC457367B70	FASTA	305	33,141
	10 20 30 40 50 60 MSVPTGWATS QGTLARALTI DGHGLHTGRR VGVRILPARP EDGVTGIAFR RVEQGRTLAT 70 80 90 100 110 120 LPVDPALRRA QPLCTMLRNA DGVGVRTVEH LLASLLACEI DHAIVELDAE EVPILDGSAT 130 140 150 160 170 180 PWVDAIRTCG RVALDAPKRF IRVLRTVVVT EGEGEQRREM RIEPAPRYEL SVRNDLRGFG 190 200 210 220 230 240 EMHWDGALTP AAFATEIAPS RSYGRVKWAV PAILAGYLRG VPILRGARPS CTASIVGKRV 250 260 270 280 290 300 LGGMRLPDEF VRHRVLDLVG DLALAGAPLL ARVSAVRPSH EMNFRLVDAL LAEPGAWQWA DFSEA

References

[1]	"Annotation of Burkholderia pseudomallei Pasteur 52237." DeShazer D., Woods D.E., Nierman W.C. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Pasteur 52237 EMBL EDO94976.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH899755 Genomic DNA. Translation: EDO94976.1.
3D structure databases
ProteinModelPortal	A8KWE6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	30410269. VBIBurPse100884_6364.
Phylogenomic databases
OMA	IAFRRVA.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
ProtoNet	Search...

Entry information

Entry name

A8KWE6_BURPS

Accession

Primary (citable) accession number: A8KWE6

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)