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A8KC70

- A8KC70_BOVIN

UniProt

A8KC70 - A8KC70_BOVIN

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Protein
Submitted name:

DVL1 protein

Gene

DVL1

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. frizzled binding Source: RefGenome
  2. protein kinase binding Source: RefGenome
  3. Rac GTPase binding Source: RefGenome

GO - Biological processi

  1. axon extension Source: RefGenome
  2. axon guidance Source: RefGenome
  3. canonical Wnt signaling pathway Source: RefGenome
  4. cochlea morphogenesis Source: RefGenome
  5. collateral sprouting Source: RefGenome
  6. convergent extension Source: RefGenome
  7. dendrite morphogenesis Source: RefGenome
  8. intracellular signal transduction Source: InterPro
  9. planar cell polarity pathway involved in neural tube closure Source: RefGenome
  10. positive regulation of transcription, DNA-templated Source: RefGenome
  11. regulation of signaling Source: RefGenome
  12. skeletal muscle acetylcholine-gated channel clustering Source: RefGenome
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DVL1 proteinImported
Gene namesi
Name:DVL1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

GO - Cellular componenti

  1. axon Source: RefGenome
  2. cell cortex Source: RefGenome
  3. clathrin-coated vesicle Source: RefGenome
  4. dendrite Source: RefGenome
  5. growth cone Source: RefGenome
  6. microtubule Source: RefGenome
  7. neuronal cell body Source: RefGenome
  8. synapse Source: RefGenome
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000014152.

Structurei

3D structure databases

ProteinModelPortaliA8KC70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PDZ (DHR) domain.UniRule annotation

Phylogenomic databases

eggNOGiNOG322275.
HOGENOMiHOG000017084.
HOVERGENiHBG005542.
KOiK02353.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.30.42.10. 1 hit.
InterProiIPR000591. DEP_dom.
IPR024580. Dishevelled_C-dom.
IPR008339. Dishevelled_fam.
IPR003351. Dishevelled_protein_dom.
IPR001158. DIX.
IPR015506. Dsh/Dvl-rel.
IPR008340. DVL-1.
IPR001478. PDZ.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10878. PTHR10878. 1 hit.
PTHR10878:SF5. PTHR10878:SF5. 1 hit.
PfamiPF00610. DEP. 1 hit.
PF02377. Dishevelled. 1 hit.
PF00778. DIX. 1 hit.
PF12316. Dsh_C. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view]
PRINTSiPR01760. DISHEVELLED.
SMARTiSM00049. DEP. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50186. DEP. 1 hit.
PS50841. DIX. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A8KC70-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TPYLVKLPVA PERVTLADFK NVLSNRPVHA YKFFFKSMDQ DFGVVKEEIS
60 70 80 90 100
DDNAKLPCFN GRVVSWLVLA EGAHSDAGSQ GTDGHTDLPP PLERTGGIGD
110 120 130 140 150
SRPPSFHPNV AGSRDGMDNE TGTESLVSHR RERARRRNRE EAARTNGHPR
160 170 180 190 200
GDRRRDLGLP PDSASTVLSS ELESSSFIDS DEDDNTSRLS SSTEQSTSSR
210 220 230 240 250
LIRKHKRRRR KQRLRQTDRA SSFSSITDST MSLNIITVTL NMERHHFLGI
260 270 280 290 300
SIVGQSNDRG DGGIYIGSIM KGGAVAADGR IEPGDMLLQV NDVNFENMSN
310 320 330 340 350
DDAVRVLREI VSQTGPISLT VAKCWDPTPR SYFTIPRADP VRPIDPAAWL
360 370 380 390 400
SHTAALTGAL PRYGTSPCSS AVTRTSSSSL TSSVPGAPQL EEAPLTVKSD
410 420 430 440 450
MGAVVRVMQL PDSGLEIRDR MWLKITIANA VIGADVVDWL YAHLEGFRER
460 470 480 490 500
REARKYASSM LKRGFLRHTV NKVTFSEQCY YVFGDLCSNL AALNLNSGSS
510 520 530 540 550
GASDQDTLAP LPHPAAPWPL GQGYPYQYPG PPPCFPPAYQ DPGFGYGSGS
560 570 580 590 600
AGSQQSEGSK SSGSTRSAGG SSRRALGREK ESRSAGAGGS GSESDHTVPS
610 620 630 640 650
GAGGSGWRER PPSQLSRGSS PRSQASAAAP GLPPLHPLTK AYSVVGGPPG
660 670 680
GPPVRELAAV PPELTGSRQS FQKAMGNPCE FFVDIM
Length:686
Mass (Da):73,714
Last modified:December 4, 2007 - v1
Checksum:iB4E8DA2E5DED2D52
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC154382 mRNA. Translation: AAI54383.1.
RefSeqiNP_001193530.1. NM_001206601.1.
UniGeneiBt.27892.

Genome annotation databases

GeneIDi523325.
KEGGibta:523325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC154382 mRNA. Translation: AAI54383.1 .
RefSeqi NP_001193530.1. NM_001206601.1.
UniGenei Bt.27892.

3D structure databases

ProteinModelPortali A8KC70.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000014152.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 523325.
KEGGi bta:523325.

Organism-specific databases

CTDi 1855.

Phylogenomic databases

eggNOGi NOG322275.
HOGENOMi HOG000017084.
HOVERGENi HBG005542.
KOi K02353.

Miscellaneous databases

NextBioi 20873714.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.30.42.10. 1 hit.
InterProi IPR000591. DEP_dom.
IPR024580. Dishevelled_C-dom.
IPR008339. Dishevelled_fam.
IPR003351. Dishevelled_protein_dom.
IPR001158. DIX.
IPR015506. Dsh/Dvl-rel.
IPR008340. DVL-1.
IPR001478. PDZ.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
PANTHERi PTHR10878. PTHR10878. 1 hit.
PTHR10878:SF5. PTHR10878:SF5. 1 hit.
Pfami PF00610. DEP. 1 hit.
PF02377. Dishevelled. 1 hit.
PF00778. DIX. 1 hit.
PF12316. Dsh_C. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view ]
PRINTSi PR01760. DISHEVELLED.
SMARTi SM00049. DEP. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view ]
SUPFAMi SSF50156. SSF50156. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50186. DEP. 1 hit.
PS50841. DIX. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: L1 HerefordImported.
    Tissue: UterusImported.

Entry informationi

Entry nameiA8KC70_BOVIN
AccessioniPrimary (citable) accession number: A8KC70
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)