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A8KC70

- A8KC70_BOVIN

UniProt

A8KC70 - A8KC70_BOVIN

Protein
Submitted name:

DVL1 protein

Gene

DVL1

Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. frizzled binding Source: RefGenome
    2. protein kinase binding Source: RefGenome
    3. Rac GTPase binding Source: RefGenome
    4. signal transducer activity Source: InterPro

    GO - Biological processi

    1. axon extension Source: RefGenome
    2. axon guidance Source: RefGenome
    3. canonical Wnt signaling pathway Source: RefGenome
    4. cochlea morphogenesis Source: RefGenome
    5. collateral sprouting Source: RefGenome
    6. convergent extension Source: RefGenome
    7. dendrite morphogenesis Source: RefGenome
    8. intracellular signal transduction Source: InterPro
    9. planar cell polarity pathway involved in neural tube closure Source: RefGenome
    10. positive regulation of transcription, DNA-templated Source: RefGenome
    11. regulation of signaling Source: RefGenome
    12. skeletal muscle acetylcholine-gated channel clustering Source: RefGenome

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    DVL1 proteinImported
    Gene namesi
    Name:DVL1Imported
    OrganismiBos taurus (Bovine)Imported
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: RefGenome
    2. cell cortex Source: RefGenome
    3. clathrin-coated vesicle Source: RefGenome
    4. dendrite Source: RefGenome
    5. growth cone Source: RefGenome
    6. microtubule Source: RefGenome
    7. neuronal cell body Source: RefGenome
    8. synapse Source: RefGenome

    Interactioni

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000014152.

    Structurei

    3D structure databases

    ProteinModelPortaliA8KC70.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PDZ (DHR) domain.UniRule annotation

    Phylogenomic databases

    eggNOGiNOG322275.
    HOGENOMiHOG000017084.
    HOVERGENiHBG005542.
    InParanoidiA8KC70.
    KOiK02353.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    2.30.42.10. 1 hit.
    InterProiIPR000591. DEP_dom.
    IPR008340. Dishevelled_1.
    IPR024580. Dishevelled_C-dom.
    IPR008339. Dishevelled_fam.
    IPR003351. Dishevelled_protein_dom.
    IPR001158. DIX.
    IPR015506. Dsh/Dvl-rel.
    IPR001478. PDZ.
    IPR029071. Ubiquitin-rel_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PANTHERiPTHR10878. PTHR10878. 1 hit.
    PTHR10878:SF5. PTHR10878:SF5. 1 hit.
    PfamiPF00610. DEP. 1 hit.
    PF02377. Dishevelled. 1 hit.
    PF00778. DIX. 1 hit.
    PF12316. Dsh_C. 1 hit.
    PF00595. PDZ. 1 hit.
    [Graphical view]
    PRINTSiPR01760. DISHEVELLED.
    SMARTiSM00049. DEP. 1 hit.
    SM00228. PDZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF50156. SSF50156. 1 hit.
    SSF54236. SSF54236. 1 hit.
    PROSITEiPS50186. DEP. 1 hit.
    PS50841. DIX. 1 hit.
    PS50106. PDZ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    A8KC70-1 [UniParc]FASTAAdd to Basket

    « Hide

    TPYLVKLPVA PERVTLADFK NVLSNRPVHA YKFFFKSMDQ DFGVVKEEIS    50
    DDNAKLPCFN GRVVSWLVLA EGAHSDAGSQ GTDGHTDLPP PLERTGGIGD 100
    SRPPSFHPNV AGSRDGMDNE TGTESLVSHR RERARRRNRE EAARTNGHPR 150
    GDRRRDLGLP PDSASTVLSS ELESSSFIDS DEDDNTSRLS SSTEQSTSSR 200
    LIRKHKRRRR KQRLRQTDRA SSFSSITDST MSLNIITVTL NMERHHFLGI 250
    SIVGQSNDRG DGGIYIGSIM KGGAVAADGR IEPGDMLLQV NDVNFENMSN 300
    DDAVRVLREI VSQTGPISLT VAKCWDPTPR SYFTIPRADP VRPIDPAAWL 350
    SHTAALTGAL PRYGTSPCSS AVTRTSSSSL TSSVPGAPQL EEAPLTVKSD 400
    MGAVVRVMQL PDSGLEIRDR MWLKITIANA VIGADVVDWL YAHLEGFRER 450
    REARKYASSM LKRGFLRHTV NKVTFSEQCY YVFGDLCSNL AALNLNSGSS 500
    GASDQDTLAP LPHPAAPWPL GQGYPYQYPG PPPCFPPAYQ DPGFGYGSGS 550
    AGSQQSEGSK SSGSTRSAGG SSRRALGREK ESRSAGAGGS GSESDHTVPS 600
    GAGGSGWRER PPSQLSRGSS PRSQASAAAP GLPPLHPLTK AYSVVGGPPG 650
    GPPVRELAAV PPELTGSRQS FQKAMGNPCE FFVDIM 686
    Length:686
    Mass (Da):73,714
    Last modified:December 4, 2007 - v1
    Checksum:iB4E8DA2E5DED2D52
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC154382 mRNA. Translation: AAI54383.1.
    RefSeqiNP_001193530.1. NM_001206601.1.
    UniGeneiBt.27892.

    Genome annotation databases

    GeneIDi523325.
    KEGGibta:523325.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC154382 mRNA. Translation: AAI54383.1 .
    RefSeqi NP_001193530.1. NM_001206601.1.
    UniGenei Bt.27892.

    3D structure databases

    ProteinModelPortali A8KC70.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000014152.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 523325.
    KEGGi bta:523325.

    Organism-specific databases

    CTDi 1855.

    Phylogenomic databases

    eggNOGi NOG322275.
    HOGENOMi HOG000017084.
    HOVERGENi HBG005542.
    InParanoidi A8KC70.
    KOi K02353.

    Miscellaneous databases

    NextBioi 20873714.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    2.30.42.10. 1 hit.
    InterProi IPR000591. DEP_dom.
    IPR008340. Dishevelled_1.
    IPR024580. Dishevelled_C-dom.
    IPR008339. Dishevelled_fam.
    IPR003351. Dishevelled_protein_dom.
    IPR001158. DIX.
    IPR015506. Dsh/Dvl-rel.
    IPR001478. PDZ.
    IPR029071. Ubiquitin-rel_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    PANTHERi PTHR10878. PTHR10878. 1 hit.
    PTHR10878:SF5. PTHR10878:SF5. 1 hit.
    Pfami PF00610. DEP. 1 hit.
    PF02377. Dishevelled. 1 hit.
    PF00778. DIX. 1 hit.
    PF12316. Dsh_C. 1 hit.
    PF00595. PDZ. 1 hit.
    [Graphical view ]
    PRINTSi PR01760. DISHEVELLED.
    SMARTi SM00049. DEP. 1 hit.
    SM00228. PDZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50156. SSF50156. 1 hit.
    SSF54236. SSF54236. 1 hit.
    PROSITEi PS50186. DEP. 1 hit.
    PS50841. DIX. 1 hit.
    PS50106. PDZ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: L1 HerefordImported.
      Tissue: UterusImported.

    Entry informationi

    Entry nameiA8KC70_BOVIN
    AccessioniPrimary (citable) accession number: A8KC70
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 4, 2007
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)