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A8KC70

- A8KC70_BOVIN

UniProt

A8KC70 - A8KC70_BOVIN

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Protein
Submitted name:

DVL1 protein

Gene
DVL1
Organism
Bos taurus (Bovine)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. frizzled binding Source: RefGenome
  2. protein kinase binding Source: RefGenome
  3. Rac GTPase binding Source: RefGenome
  4. signal transducer activity Source: InterPro

GO - Biological processi

  1. axon extension Source: RefGenome
  2. axon guidance Source: RefGenome
  3. canonical Wnt signaling pathway Source: RefGenome
  4. cochlea morphogenesis Source: RefGenome
  5. collateral sprouting Source: RefGenome
  6. convergent extension Source: RefGenome
  7. dendrite morphogenesis Source: RefGenome
  8. intracellular signal transduction Source: InterPro
  9. planar cell polarity pathway involved in neural tube closure Source: RefGenome
  10. positive regulation of transcription, DNA-templated Source: RefGenome
  11. regulation of signaling Source: RefGenome
  12. skeletal muscle acetylcholine-gated channel clustering Source: RefGenome
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DVL1 proteinImported
Gene namesi
Name:DVL1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

GO - Cellular componenti

  1. axon Source: RefGenome
  2. cell cortex Source: RefGenome
  3. clathrin-coated vesicle Source: RefGenome
  4. dendrite Source: RefGenome
  5. growth cone Source: RefGenome
  6. microtubule Source: RefGenome
  7. neuronal cell body Source: RefGenome
  8. synapse Source: RefGenome
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000014152.

Structurei

3D structure databases

ProteinModelPortaliA8KC70.

Family & Domainsi

Sequence similaritiesi

Contains 1 PDZ (DHR) domain.UniRule annotation

Phylogenomic databases

eggNOGiNOG322275.
HOGENOMiHOG000017084.
HOVERGENiHBG005542.
InParanoidiA8KC70.
KOiK02353.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.30.42.10. 1 hit.
InterProiIPR000591. DEP_dom.
IPR008340. Dishevelled_1.
IPR024580. Dishevelled_C-dom.
IPR008339. Dishevelled_fam.
IPR003351. Dishevelled_protein_dom.
IPR001158. DIX.
IPR015506. Dsh/Dvl-rel.
IPR001478. PDZ.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR10878. PTHR10878. 1 hit.
PTHR10878:SF5. PTHR10878:SF5. 1 hit.
PfamiPF00610. DEP. 1 hit.
PF02377. Dishevelled. 1 hit.
PF00778. DIX. 1 hit.
PF12316. Dsh_C. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view]
PRINTSiPR01760. DISHEVELLED.
SMARTiSM00049. DEP. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50186. DEP. 1 hit.
PS50841. DIX. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A8KC70-1 [UniParc]FASTAAdd to Basket

« Hide

TPYLVKLPVA PERVTLADFK NVLSNRPVHA YKFFFKSMDQ DFGVVKEEIS    50
DDNAKLPCFN GRVVSWLVLA EGAHSDAGSQ GTDGHTDLPP PLERTGGIGD 100
SRPPSFHPNV AGSRDGMDNE TGTESLVSHR RERARRRNRE EAARTNGHPR 150
GDRRRDLGLP PDSASTVLSS ELESSSFIDS DEDDNTSRLS SSTEQSTSSR 200
LIRKHKRRRR KQRLRQTDRA SSFSSITDST MSLNIITVTL NMERHHFLGI 250
SIVGQSNDRG DGGIYIGSIM KGGAVAADGR IEPGDMLLQV NDVNFENMSN 300
DDAVRVLREI VSQTGPISLT VAKCWDPTPR SYFTIPRADP VRPIDPAAWL 350
SHTAALTGAL PRYGTSPCSS AVTRTSSSSL TSSVPGAPQL EEAPLTVKSD 400
MGAVVRVMQL PDSGLEIRDR MWLKITIANA VIGADVVDWL YAHLEGFRER 450
REARKYASSM LKRGFLRHTV NKVTFSEQCY YVFGDLCSNL AALNLNSGSS 500
GASDQDTLAP LPHPAAPWPL GQGYPYQYPG PPPCFPPAYQ DPGFGYGSGS 550
AGSQQSEGSK SSGSTRSAGG SSRRALGREK ESRSAGAGGS GSESDHTVPS 600
GAGGSGWRER PPSQLSRGSS PRSQASAAAP GLPPLHPLTK AYSVVGGPPG 650
GPPVRELAAV PPELTGSRQS FQKAMGNPCE FFVDIM 686
Length:686
Mass (Da):73,714
Last modified:December 4, 2007 - v1
Checksum:iB4E8DA2E5DED2D52
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC154382 mRNA. Translation: AAI54383.1.
RefSeqiNP_001193530.1. NM_001206601.1.
UniGeneiBt.27892.

Genome annotation databases

GeneIDi523325.
KEGGibta:523325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC154382 mRNA. Translation: AAI54383.1 .
RefSeqi NP_001193530.1. NM_001206601.1.
UniGenei Bt.27892.

3D structure databases

ProteinModelPortali A8KC70.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000014152.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 523325.
KEGGi bta:523325.

Organism-specific databases

CTDi 1855.

Phylogenomic databases

eggNOGi NOG322275.
HOGENOMi HOG000017084.
HOVERGENi HBG005542.
InParanoidi A8KC70.
KOi K02353.

Miscellaneous databases

NextBioi 20873714.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
2.30.42.10. 1 hit.
InterProi IPR000591. DEP_dom.
IPR008340. Dishevelled_1.
IPR024580. Dishevelled_C-dom.
IPR008339. Dishevelled_fam.
IPR003351. Dishevelled_protein_dom.
IPR001158. DIX.
IPR015506. Dsh/Dvl-rel.
IPR001478. PDZ.
IPR029071. Ubiquitin-rel_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
PANTHERi PTHR10878. PTHR10878. 1 hit.
PTHR10878:SF5. PTHR10878:SF5. 1 hit.
Pfami PF00610. DEP. 1 hit.
PF02377. Dishevelled. 1 hit.
PF00778. DIX. 1 hit.
PF12316. Dsh_C. 1 hit.
PF00595. PDZ. 1 hit.
[Graphical view ]
PRINTSi PR01760. DISHEVELLED.
SMARTi SM00049. DEP. 1 hit.
SM00228. PDZ. 1 hit.
[Graphical view ]
SUPFAMi SSF50156. SSF50156. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEi PS50186. DEP. 1 hit.
PS50841. DIX. 1 hit.
PS50106. PDZ. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: L1 HerefordImported.
    Tissue: UterusImported.

Entry informationi

Entry nameiA8KC70_BOVIN
AccessioniPrimary (citable) accession number: A8KC70
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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