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A8KBL5

- S38AB_DANRE

UniProt

A8KBL5 - S38AB_DANRE

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Protein
Putative sodium-coupled neutral amino acid transporter 11
Gene
slc38a11, zgc:110221
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Putative sodium-dependent amino acid/proton antiporter By similarity.

GO - Biological processi

  1. amino acid transport Source: UniProtKB-KW
  2. sodium ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 11
Alternative name(s):
Solute carrier family 38 member 11
Gene namesi
Name:slc38a11
ORF Names:zgc:110221
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-050417-122. slc38a11.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei22 – 4221Helical; Reviewed prediction
Add
BLAST
Topological domaini43 – 519Extracellular Reviewed prediction
Transmembranei52 – 7221Helical; Reviewed prediction
Add
BLAST
Topological domaini73 – 9321Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei94 – 11421Helical; Reviewed prediction
Add
BLAST
Topological domaini115 – 14228Extracellular Reviewed prediction
Add
BLAST
Transmembranei143 – 16321Helical; Reviewed prediction
Add
BLAST
Topological domaini164 – 1641Cytoplasmic Reviewed prediction
Transmembranei165 – 18521Helical; Reviewed prediction
Add
BLAST
Topological domaini186 – 19914Extracellular Reviewed prediction
Add
BLAST
Transmembranei200 – 22021Helical; Reviewed prediction
Add
BLAST
Topological domaini221 – 24525Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei246 – 26621Helical; Reviewed prediction
Add
BLAST
Topological domaini267 – 28519Extracellular Reviewed prediction
Add
BLAST
Transmembranei286 – 30621Helical; Reviewed prediction
Add
BLAST
Topological domaini307 – 32317Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei324 – 34421Helical; Reviewed prediction
Add
BLAST
Topological domaini345 – 3451Extracellular Reviewed prediction
Transmembranei346 – 36621Helical; Reviewed prediction
Add
BLAST
Topological domaini367 – 38822Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei389 – 40921Helical; Reviewed prediction
Add
BLAST
Topological domaini410 – 44839Extracellular Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448Putative sodium-coupled neutral amino acid transporter 11
PRO_0000326062Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi425 – 4251N-linked (GlcNAc...) Reviewed prediction
Glycosylationi440 – 4401N-linked (GlcNAc...) Reviewed prediction
Glycosylationi444 – 4441N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

BgeeiA8KBL5.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0814.
GeneTreeiENSGT00710000106531.
HOVERGENiHBG106990.
InParanoidiQ568L8.
KOiK14997.
OMAiMESERSC.
OrthoDBiEOG7SBNNK.
TreeFamiTF328787.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8KBL5-1 [UniParc]FASTAAdd to Basket

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MESERSCLLS SHDAGKGGSS SVSSASFNFI NSIIGSGIIG LPYSMSQAGL    50
PMGLLLLILV AFITDYSIIL LVRGGNLSGT HSYQSLVRST FGQIGYIIVS 100
VLQFLYPFIA MISYNIIAGD TLTKVFMRIP GVGPGNILTE RHFVIAMSTV 150
LFTLPLSLYR DIAKLGKVSL LSMILTFGIL MTVVVRAATL GPQIPASDDA 200
WVFARWNAIQ AVAVMSFALI CHHNSFMIYG SLQEPTLSRW SLVTHISVGS 250
SVLVSAVFAA AGYATFTVYT QGDIFENYCR SDNLATFGRF CYGVSIITTF 300
PLECFVTREV ISNALFKGGE LSKSSHVIIT LVIISATTAI SLSYDCLGIV 350
LELNGILSAV PLMFIFPSAC FLKLSNERWC RGENLIASMI LVAGVFVMII 400
GLIMMALFPQ DCSHGAEMFY CSASNTSSTA SPSNILQFIN TTQNTSIV 448
Length:448
Mass (Da):48,300
Last modified:March 18, 2008 - v2
Checksum:i8A9A031D52A17224
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1111M → V in AAH92805. 1 Publication
Sequence conflicti332 – 3321V → G in AAH92805. 1 Publication
Sequence conflicti342 – 3421L → P in AAH92805. 1 Publication
Sequence conflicti426 – 4261T → I in AAI54163. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092805 mRNA. Translation: AAH92805.1.
BC154162 mRNA. Translation: AAI54163.1.
RefSeqiNP_001017644.1. NM_001017644.1.
UniGeneiDr.151480.

Genome annotation databases

EnsembliENSDART00000058892; ENSDARP00000058891; ENSDARG00000040257.
ENSDART00000125269; ENSDARP00000112271; ENSDARG00000089280.
GeneIDi550337.
KEGGidre:550337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092805 mRNA. Translation: AAH92805.1 .
BC154162 mRNA. Translation: AAI54163.1 .
RefSeqi NP_001017644.1. NM_001017644.1.
UniGenei Dr.151480.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000058892 ; ENSDARP00000058891 ; ENSDARG00000040257 .
ENSDART00000125269 ; ENSDARP00000112271 ; ENSDARG00000089280 .
GeneIDi 550337.
KEGGi dre:550337.

Organism-specific databases

CTDi 151258.
ZFINi ZDB-GENE-050417-122. slc38a11.

Phylogenomic databases

eggNOGi COG0814.
GeneTreei ENSGT00710000106531.
HOVERGENi HBG106990.
InParanoidi Q568L8.
KOi K14997.
OMAi MESERSC.
OrthoDBi EOG7SBNNK.
TreeFami TF328787.

Miscellaneous databases

NextBioi 20879594.
PROi A8KBL5.

Gene expression databases

Bgeei A8KBL5.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo and Ovary.

Entry informationi

Entry nameiS38AB_DANRE
AccessioniPrimary (citable) accession number: A8KBL5
Secondary accession number(s): Q568L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: May 14, 2014
This is version 39 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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