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A8KBL5

- S38AB_DANRE

UniProt

A8KBL5 - S38AB_DANRE

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Protein

Putative sodium-coupled neutral amino acid transporter 11

Gene

slc38a11

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Putative sodium-dependent amino acid/proton antiporter.By similarity

GO - Biological processi

  1. amino acid transport Source: UniProtKB-KW
  2. sodium ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 11
Alternative name(s):
Solute carrier family 38 member 11
Gene namesi
Name:slc38a11
ORF Names:zgc:110221
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 9

Organism-specific databases

ZFINiZDB-GENE-050417-122. slc38a11.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448Putative sodium-coupled neutral amino acid transporter 11PRO_0000326062Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi425 – 4251N-linked (GlcNAc...)Sequence Analysis
Glycosylationi440 – 4401N-linked (GlcNAc...)Sequence Analysis
Glycosylationi444 – 4441N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

BgeeiA8KBL5.

Structurei

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini43 – 519ExtracellularSequence Analysis
Topological domaini73 – 9321CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini115 – 14228ExtracellularSequence AnalysisAdd
BLAST
Topological domaini164 – 1641CytoplasmicSequence Analysis
Topological domaini186 – 19914ExtracellularSequence AnalysisAdd
BLAST
Topological domaini221 – 24525CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini267 – 28519ExtracellularSequence AnalysisAdd
BLAST
Topological domaini307 – 32317CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini345 – 3451ExtracellularSequence Analysis
Topological domaini367 – 38822CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini410 – 44839ExtracellularSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4221HelicalSequence AnalysisAdd
BLAST
Transmembranei52 – 7221HelicalSequence AnalysisAdd
BLAST
Transmembranei94 – 11421HelicalSequence AnalysisAdd
BLAST
Transmembranei143 – 16321HelicalSequence AnalysisAdd
BLAST
Transmembranei165 – 18521HelicalSequence AnalysisAdd
BLAST
Transmembranei200 – 22021HelicalSequence AnalysisAdd
BLAST
Transmembranei246 – 26621HelicalSequence AnalysisAdd
BLAST
Transmembranei286 – 30621HelicalSequence AnalysisAdd
BLAST
Transmembranei324 – 34421HelicalSequence AnalysisAdd
BLAST
Transmembranei346 – 36621HelicalSequence AnalysisAdd
BLAST
Transmembranei389 – 40921HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0814.
GeneTreeiENSGT00760000119147.
HOVERGENiHBG106990.
InParanoidiA8KBL5.
KOiK14997.
OMAiMESERSC.
OrthoDBiEOG7SBNNK.
TreeFamiTF328787.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8KBL5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESERSCLLS SHDAGKGGSS SVSSASFNFI NSIIGSGIIG LPYSMSQAGL
60 70 80 90 100
PMGLLLLILV AFITDYSIIL LVRGGNLSGT HSYQSLVRST FGQIGYIIVS
110 120 130 140 150
VLQFLYPFIA MISYNIIAGD TLTKVFMRIP GVGPGNILTE RHFVIAMSTV
160 170 180 190 200
LFTLPLSLYR DIAKLGKVSL LSMILTFGIL MTVVVRAATL GPQIPASDDA
210 220 230 240 250
WVFARWNAIQ AVAVMSFALI CHHNSFMIYG SLQEPTLSRW SLVTHISVGS
260 270 280 290 300
SVLVSAVFAA AGYATFTVYT QGDIFENYCR SDNLATFGRF CYGVSIITTF
310 320 330 340 350
PLECFVTREV ISNALFKGGE LSKSSHVIIT LVIISATTAI SLSYDCLGIV
360 370 380 390 400
LELNGILSAV PLMFIFPSAC FLKLSNERWC RGENLIASMI LVAGVFVMII
410 420 430 440
GLIMMALFPQ DCSHGAEMFY CSASNTSSTA SPSNILQFIN TTQNTSIV
Length:448
Mass (Da):48,300
Last modified:March 18, 2008 - v2
Checksum:i8A9A031D52A17224
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1111M → V in AAH92805. 1 PublicationCurated
Sequence conflicti332 – 3321V → G in AAH92805. 1 PublicationCurated
Sequence conflicti342 – 3421L → P in AAH92805. 1 PublicationCurated
Sequence conflicti426 – 4261T → I in AAI54163. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092805 mRNA. Translation: AAH92805.1.
BC154162 mRNA. Translation: AAI54163.1.
RefSeqiNP_001017644.1. NM_001017644.1.
UniGeneiDr.151480.

Genome annotation databases

EnsembliENSDART00000058892; ENSDARP00000058891; ENSDARG00000040257.
ENSDART00000125269; ENSDARP00000112271; ENSDARG00000089280.
GeneIDi550337.
KEGGidre:550337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC092805 mRNA. Translation: AAH92805.1 .
BC154162 mRNA. Translation: AAI54163.1 .
RefSeqi NP_001017644.1. NM_001017644.1.
UniGenei Dr.151480.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000058892 ; ENSDARP00000058891 ; ENSDARG00000040257 .
ENSDART00000125269 ; ENSDARP00000112271 ; ENSDARG00000089280 .
GeneIDi 550337.
KEGGi dre:550337.

Organism-specific databases

CTDi 151258.
ZFINi ZDB-GENE-050417-122. slc38a11.

Phylogenomic databases

eggNOGi COG0814.
GeneTreei ENSGT00760000119147.
HOVERGENi HBG106990.
InParanoidi A8KBL5.
KOi K14997.
OMAi MESERSC.
OrthoDBi EOG7SBNNK.
TreeFami TF328787.

Miscellaneous databases

NextBioi 20879594.
PROi A8KBL5.

Gene expression databases

Bgeei A8KBL5.

Family and domain databases

InterProi IPR013057. AA_transpt_TM.
[Graphical view ]
Pfami PF01490. Aa_trans. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo and Ovary.

Entry informationi

Entry nameiS38AB_DANRE
AccessioniPrimary (citable) accession number: A8KBL5
Secondary accession number(s): Q568L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 29, 2014
This is version 41 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3