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Protein

Putative sodium-coupled neutral amino acid transporter 11

Gene

slc38a11

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Putative sodium-dependent amino acid/proton antiporter.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sodium-coupled neutral amino acid transporter 11
Alternative name(s):
Solute carrier family 38 member 11
Gene namesi
ORF Names:zgc:110221
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-050417-122. slc38a11.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Transmembranei165 – 185HelicalSequence analysisAdd BLAST21
Transmembranei200 – 220HelicalSequence analysisAdd BLAST21
Transmembranei246 – 266HelicalSequence analysisAdd BLAST21
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei324 – 344HelicalSequence analysisAdd BLAST21
Transmembranei346 – 366HelicalSequence analysisAdd BLAST21
Transmembranei389 – 409HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003260621 – 448Putative sodium-coupled neutral amino acid transporter 11Add BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi425N-linked (GlcNAc...)Sequence analysis1
Glycosylationi440N-linked (GlcNAc...)Sequence analysis1
Glycosylationi444N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA8KBL5.

Expressioni

Gene expression databases

BgeeiENSDARG00000040257.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112271.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1305. Eukaryota.
COG0814. LUCA.
HOVERGENiHBG106990.
InParanoidiA8KBL5.
KOiK14997.
TreeFamiTF328787.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8KBL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESERSCLLS SHDAGKGGSS SVSSASFNFI NSIIGSGIIG LPYSMSQAGL
60 70 80 90 100
PMGLLLLILV AFITDYSIIL LVRGGNLSGT HSYQSLVRST FGQIGYIIVS
110 120 130 140 150
VLQFLYPFIA MISYNIIAGD TLTKVFMRIP GVGPGNILTE RHFVIAMSTV
160 170 180 190 200
LFTLPLSLYR DIAKLGKVSL LSMILTFGIL MTVVVRAATL GPQIPASDDA
210 220 230 240 250
WVFARWNAIQ AVAVMSFALI CHHNSFMIYG SLQEPTLSRW SLVTHISVGS
260 270 280 290 300
SVLVSAVFAA AGYATFTVYT QGDIFENYCR SDNLATFGRF CYGVSIITTF
310 320 330 340 350
PLECFVTREV ISNALFKGGE LSKSSHVIIT LVIISATTAI SLSYDCLGIV
360 370 380 390 400
LELNGILSAV PLMFIFPSAC FLKLSNERWC RGENLIASMI LVAGVFVMII
410 420 430 440
GLIMMALFPQ DCSHGAEMFY CSASNTSSTA SPSNILQFIN TTQNTSIV
Length:448
Mass (Da):48,300
Last modified:March 18, 2008 - v2
Checksum:i8A9A031D52A17224
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti111M → V in AAH92805 (Ref. 1) Curated1
Sequence conflicti332V → G in AAH92805 (Ref. 1) Curated1
Sequence conflicti342L → P in AAH92805 (Ref. 1) Curated1
Sequence conflicti426T → I in AAI54163 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092805 mRNA. Translation: AAH92805.1.
BC154162 mRNA. Translation: AAI54163.1.
RefSeqiNP_001017644.1. NM_001017644.1.
UniGeneiDr.151480.

Genome annotation databases

GeneIDi550337.
KEGGidre:550337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC092805 mRNA. Translation: AAH92805.1.
BC154162 mRNA. Translation: AAI54163.1.
RefSeqiNP_001017644.1. NM_001017644.1.
UniGeneiDr.151480.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000112271.

Proteomic databases

PaxDbiA8KBL5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi550337.
KEGGidre:550337.

Organism-specific databases

CTDi151258.
ZFINiZDB-GENE-050417-122. slc38a11.

Phylogenomic databases

eggNOGiKOG1305. Eukaryota.
COG0814. LUCA.
HOVERGENiHBG106990.
InParanoidiA8KBL5.
KOiK14997.
TreeFamiTF328787.

Miscellaneous databases

PROiA8KBL5.

Gene expression databases

BgeeiENSDARG00000040257.

Family and domain databases

InterProiIPR013057. AA_transpt_TM.
[Graphical view]
PfamiPF01490. Aa_trans. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiS38AB_DANRE
AccessioniPrimary (citable) accession number: A8KBL5
Secondary accession number(s): Q568L8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: November 2, 2016
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.