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Protein
Submitted name:

RAP1A, member of RAS oncogene family

Gene

RAP1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
RAP1A, member of RAS oncogene familyImported
Submitted name:
Ras-related protein Rap-1AImported
Submitted name:
cDNA FLJ75985, highly similar to Homo sapiens RAP1A, member of RAS oncogene family (RAP1A), transcript variant 2, mRNAImported
Gene namesi
Name:RAP1AImported
ORF Names:hCG_1818872Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000116473.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34217

PTM / Processingi

Proteomic databases

PRIDEiA8KAH9

Expressioni

Gene expression databases

BgeeiENSG00000116473
ExpressionAtlasiA8KAH9 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA8KAH9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395 Eukaryota
COG1100 LUCA
HOVERGENiHBG009351
KOiK04353
OMAiQINRQMP
OrthoDBiEOG091G0OOG

Family and domain databases

CDDicd04175 Rap1, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR038851 Rap1
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type
PANTHERiPTHR24070 PTHR24070, 1 hit
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51421 RAS, 1 hit

Sequencei

Sequence statusi: Complete.

A8KAH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDCQQ
60 70 80 90 100
CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI
110 120 130 140 150
LRVKDTEDVP MILVGNKCDL EDERVVGKEQ GQNLARQWCN CAFLESSAKS
160 170 180
KINVNEIFYD LVRQINRKTP VEKKKPKKKS CLLL
Length:184
Mass (Da):20,987
Last modified:February 5, 2008 - v1
Checksum:i42C39290C98E0A92
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293044 mRNA Translation: BAF85733.1
AB451235 mRNA Translation: BAG70049.1
AB451360 mRNA Translation: BAG70174.1
CH471122 Genomic DNA Translation: EAW56503.1
RefSeqiNP_001010935.1, NM_001010935.2
NP_001278825.1, NM_001291896.1
NP_002875.1, NM_002884.3
XP_016857451.1, XM_017001962.1
XP_016857452.1, XM_017001963.1
XP_016857453.1, XM_017001964.1
UniGeneiHs.190334
Hs.586618

Genome annotation databases

GeneIDi5906
KEGGihsa:5906

Similar proteinsi

Entry informationi

Entry nameiA8KAH9_HUMAN
AccessioniPrimary (citable) accession number: A8KAH9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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