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Protein
Submitted name:

cDNA FLJ75059, highly similar to Homo sapiens phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (PFAS), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ75059, highly similar to Homo sapiens phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (PFAS), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33205.

PTM / Processingi

Proteomic databases

PaxDbiA8K9T9.
PeptideAtlasiA8K9T9.
PRIDEiA8K9T9.

Expressioni

Gene expression databases

GenevisibleiA8K9T9. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000313490.

Structurei

3D structure databases

ProteinModelPortaliA8K9T9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1064 – 1336273Glutamine amidotransferase type-1InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1907. Eukaryota.
COG0046. LUCA.
COG0047. LUCA.
HOVERGENiHBG108309.
KOiK01952.

Family and domain databases

Gene3Di3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
HAMAPiMF_00419. PurL_1. 1 hit.
InterProiIPR010918. AIR_synth_C_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM-like_N.
[Graphical view]
PfamiPF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56042. SSF56042. 2 hits.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K9T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPVLHFYVR PSGHEGAAPG HTRRKLQGKL PELQGVETEL CYNVNWTAEA
60 70 80 90 100
LPSAEETKKL MWLFGCPLLL DDVARESWLL PGSNDLLLEV GPRLNFSTPT
110 120 130 140 150
STNIVSVCRA TGLGPVDRVE TTRRYRLSFA HPPSAEVEAI ALATLHDRMT
160 170 180 190 200
EQHFPHPIQS FSPESMPEPL NGPINILGEG RLALEKANQE LGLALDSWDL
210 220 230 240 250
DFYTKRFQEL QRNPSTVEAF DLAQSNSEHS RHWFFKGQLH VDGQKLVHSL
260 270 280 290 300
FESIMSTQES SNPNNVLKFC DNSSAIQGKE VRFLRPEDPT RPSRFQQQQG
310 320 330 340 350
LRHVVFTAET HNFPTGVCPF SGATTGTGGR IRDVQCTGRG AHVVAGTAGY
360 370 380 390 400
CFGNLHIPGY NLPWEDPSFQ YPGNFARPLE VAIEASNGAS DYGNKFGEPV
410 420 430 440 450
LAGFARSLGL QLPDGQRREW IKPIMFSGGI GSMEADHISK EAPEPGMEVV
460 470 480 490 500
KVGGPVYRIG VGGGAASSVQ VQGDNTSDLD FGAVQRGDPE MEQKMNRVIR
510 520 530 540 550
ACVEAPKGNP ICSLHDQGAG GNGNVLKELS DPAGAIIYTS RFQLGDPTLN
560 570 580 590 600
ALEIWGAEYQ ESNALLLRSP NRDFLTHVSA RERCPACFVG TITGDRRIVL
610 620 630 640 650
VDDRECPVRR NGQGDAPPTP LPTPVDLELG WVLGKMPRKE FFLQRKPPML
660 670 680 690 700
QPLALPPGLS VHQALERVLR LPAVASKRYL TNKVDRSVGG LVAQQQCVGP
710 720 730 740 750
LQTPLADVAV VALSHEELIG AATALGEQPV KSLLDPKVAA RLAVAEALTN
760 770 780 790 800
LVFALVTDLR DVKCSGNWMW AAKLPGEGAA LADACEAMVA VMAALGVAVD
810 820 830 840 850
GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP DLKHPEGRGH
860 870 880 890 900
LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR AFSITQGLLK
910 920 930 940 950
DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD VLSVLFAEEP
960 970 980 990 1000
GLVLEVQEPD LAQVLKRYRD AGLHCLELGH TGEAGPHAMV RVSVNGAVVL
1010 1020 1030 1040 1050
EEPVGELRAL WEETSFQLDR LQAEPRCVAE EERGLRERMG PSYCLPPTFP
1060 1070 1080 1090 1100
KASVPREPGG PSPRVAILRE EGSNGDREMA DAFHLAGFEV WDVTMQDLCS
1110 1120 1130 1140 1150
GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG AELRRFRKRP
1160 1170 1180 1190 1200
DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP GLLLHHNLSG
1210 1220 1230 1240 1250
RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF SSPELQAQIE
1260 1270 1280 1290 1300
ARGLAPLHWA DDDGNPTEQY PLNPNGSPGG VAGICSCDGR HLAVMPHPER
1310 1320 1330
AVRPWQWAWR PPPFDTLTTS PWLQLFINAR NWTLEGSC
Length:1,338
Mass (Da):144,643
Last modified:December 4, 2007 - v1
Checksum:i9EC9A465396B59AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292804 mRNA. Translation: BAF85493.1.
RefSeqiNP_036525.1. NM_012393.2.
UniGeneiHs.573976.

Genome annotation databases

GeneIDi5198.
KEGGihsa:5198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK292804 mRNA. Translation: BAF85493.1.
RefSeqiNP_036525.1. NM_012393.2.
UniGeneiHs.573976.

3D structure databases

ProteinModelPortaliA8K9T9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000313490.

Proteomic databases

PaxDbiA8K9T9.
PeptideAtlasiA8K9T9.
PRIDEiA8K9T9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5198.
KEGGihsa:5198.

Organism-specific databases

CTDi5198.
PharmGKBiPA33205.

Phylogenomic databases

eggNOGiKOG1907. Eukaryota.
COG0046. LUCA.
COG0047. LUCA.
HOVERGENiHBG108309.
KOiK01952.

Miscellaneous databases

GenomeRNAii5198.

Gene expression databases

GenevisibleiA8K9T9. HS.

Family and domain databases

Gene3Di3.30.1330.10. 2 hits.
3.40.50.880. 1 hit.
HAMAPiMF_00419. PurL_1. 1 hit.
InterProiIPR010918. AIR_synth_C_dom.
IPR029062. Class_I_gatase-like.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR016188. PurM-like_N.
[Graphical view]
PfamiPF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56042. SSF56042. 2 hits.
TIGRFAMsiTIGR01735. FGAM_synt. 1 hit.
PROSITEiPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8K9T9_HUMAN
AccessioniPrimary (citable) accession number: A8K9T9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: July 6, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.