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Protein
Submitted name:

Band 4.1-like protein 3

Gene

EPB41L3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Band 4.1-like protein 3Imported
Submitted name:
cDNA FLJ77757Imported
Gene namesi
Name:EPB41L3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000082397.16
HGNCiHGNC:3380 EPB41L3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000082397

PTM / Processingi

Proteomic databases

MaxQBiA8K968
PeptideAtlasiA8K968

Expressioni

Gene expression databases

BgeeiENSG00000082397

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 282FERMInterPro annotationAdd BLAST282

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili380 – 400Sequence analysisAdd BLAST21
Coiled coili431 – 451Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118823
HOGENOMiHOG000228840
HOVERGENiHBG007777

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR030691 Band4.1-L3
IPR008379 Band_4.1_C
IPR019749 Band_41_domain
IPR000798 Ez/rad/moesin-like
IPR014847 FERM-adjacent
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR011993 PH-like_dom_sf
IPR007477 SAB_dom
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR23280:SF20 PTHR23280:SF20, 3 hits
PfamiView protein in Pfam
PF05902 4_1_CTD, 1 hit
PF08736 FA, 1 hit
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF04382 SAB, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM01195 FA, 1 hit
SM01196 FERM_C, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00660 FERM_1, 1 hit
PS00661 FERM_2, 1 hit
PS50057 FERM_3, 1 hit

Sequencei

Sequence statusi: Complete.

A8K968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQCKVILLDG SEYTCDVEKR SRGQVLFDKV CEHLNLLEKD YFGLTYRDAE
60 70 80 90 100
NQKNWLDPAK EIKKQVRSGA WHFSFNVKFY PPDPAQLSED ITRYYLCLQL
110 120 130 140 150
RDDIVSGRLP CSFVTLALLG SYTVQSELGD YDPDECGSDY ISEFRFAPNH
160 170 180 190 200
TKELEDKVIE LHKSHRGMTP AEAEMHFLEN AKKLSMYGVD LHHAKDSEGV
210 220 230 240 250
EIMLGVCASG LLIYRDRLRI NRFAWPKVLK ISYKRNNFYI KIRPGEFEQF
260 270 280 290 300
ESTIGFKLPN HRAAKRLWKV CVEHHTFFRL LLPEAPPKKF LTLGSKFRYS
310 320 330 340 350
GRTQAQTRRA SALIDRPAPY FERSSSKRYT MSRSLDGASV NENHEIYMKD
360 370 380 390 400
SMSAAEVGTG QYATTKGISQ TNLITTVTPE KKAEEERDEE EDKRRKGEEV
410 420 430 440 450
TPISAIRHEG KTDSERTDTA ADGETTATEE LEKTQDDLMK HQTNISELKR
460 470 480 490 500
TFLETSTDTA VTNEWEKRLS TSPVRLAARQ EDAPMIEPLV PEEKMETKTE
510 520 530 540 550
SSGIETEPTV HHLPLSTEKV VQETVLVEER RVVHASGDAS YSAGDSGDAA
560 570 580 590 600
AQPAFTGIKG KEGSALTEGA KEEGGEEVAK AVLEQEETAA ASRERQEEQS
610 620 630 640 650
AAIHISETLE QKPHFESSTV KTETISFGSV SPGGVKLEIS TKEVPVVHTE
660 670 680 690 700
TKTITYESSQ VDPGTDLEPG VLMSAQTITS ETTSTTTTTH ITKTVKGGIS
710 720 730 740 750
ETRIEKRIVI TGDADIDHDQ ALAQAIKEAK EQHPDMSVTK VVVHKETEIT

PEDGED
Length:756
Mass (Da):84,712
Last modified:December 4, 2007 - v1
Checksum:i2B0C5591EA711C97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001032 Genomic DNA No translation available.
AP005059 Genomic DNA No translation available.
AP005671 Genomic DNA No translation available.
AK292583 mRNA Translation: BAF85272.1
RefSeqiNP_001268464.1, NM_001281535.1
XP_016881148.1, XM_017025659.1
UniGeneiHs.213394

Genome annotation databases

EnsembliENST00000545076; ENSP00000488626; ENSG00000082397
GeneIDi23136

Similar proteinsi

Entry informationi

Entry nameiA8K968_HUMAN
AccessioniPrimary (citable) accession number: A8K968
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 25, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health