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Protein
Submitted name:

Band 4.1-like protein 3

Gene

EPB41L3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Band 4.1-like protein 3Imported
Submitted name:
cDNA FLJ77757Imported
Gene namesi
Name:EPB41L3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

HGNCiHGNC:3380. EPB41L3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA8K968.

Expressioni

Gene expression databases

BgeeiA8K968.
ExpressionAtlasiA8K968. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 282282FERMInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains FERM domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118823.
HOGENOMiHOG000228840.
HOVERGENiHBG007777.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR030691. Band4.1-L3.
IPR008379. Band_4.1_C.
IPR019749. Band_41_domain.
IPR000798. Ez/rad/moesin-like.
IPR014847. FERM-adjacent.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR011993. PH_dom-like.
IPR007477. SAB_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR23280:SF20. PTHR23280:SF20. 1 hit.
PfamiPF05902. 4_1_CTD. 1 hit.
PF08736. FA. 1 hit.
PF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF04382. SAB. 1 hit.
[Graphical view]
PRINTSiPR00935. BAND41.
PR00661. ERMFAMILY.
SMARTiSM00295. B41. 1 hit.
SM01195. FA. 1 hit.
SM01196. FERM_C. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS00660. FERM_1. 1 hit.
PS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQCKVILLDG SEYTCDVEKR SRGQVLFDKV CEHLNLLEKD YFGLTYRDAE
60 70 80 90 100
NQKNWLDPAK EIKKQVRSGA WHFSFNVKFY PPDPAQLSED ITRYYLCLQL
110 120 130 140 150
RDDIVSGRLP CSFVTLALLG SYTVQSELGD YDPDECGSDY ISEFRFAPNH
160 170 180 190 200
TKELEDKVIE LHKSHRGMTP AEAEMHFLEN AKKLSMYGVD LHHAKDSEGV
210 220 230 240 250
EIMLGVCASG LLIYRDRLRI NRFAWPKVLK ISYKRNNFYI KIRPGEFEQF
260 270 280 290 300
ESTIGFKLPN HRAAKRLWKV CVEHHTFFRL LLPEAPPKKF LTLGSKFRYS
310 320 330 340 350
GRTQAQTRRA SALIDRPAPY FERSSSKRYT MSRSLDGASV NENHEIYMKD
360 370 380 390 400
SMSAAEVGTG QYATTKGISQ TNLITTVTPE KKAEEERDEE EDKRRKGEEV
410 420 430 440 450
TPISAIRHEG KTDSERTDTA ADGETTATEE LEKTQDDLMK HQTNISELKR
460 470 480 490 500
TFLETSTDTA VTNEWEKRLS TSPVRLAARQ EDAPMIEPLV PEEKMETKTE
510 520 530 540 550
SSGIETEPTV HHLPLSTEKV VQETVLVEER RVVHASGDAS YSAGDSGDAA
560 570 580 590 600
AQPAFTGIKG KEGSALTEGA KEEGGEEVAK AVLEQEETAA ASRERQEEQS
610 620 630 640 650
AAIHISETLE QKPHFESSTV KTETISFGSV SPGGVKLEIS TKEVPVVHTE
660 670 680 690 700
TKTITYESSQ VDPGTDLEPG VLMSAQTITS ETTSTTTTTH ITKTVKGGIS
710 720 730 740 750
ETRIEKRIVI TGDADIDHDQ ALAQAIKEAK EQHPDMSVTK VVVHKETEIT

PEDGED
Length:756
Mass (Da):84,712
Last modified:December 4, 2007 - v1
Checksum:i2B0C5591EA711C97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001032 Genomic DNA. No translation available.
AP005059 Genomic DNA. No translation available.
AP005671 Genomic DNA. No translation available.
AK292583 mRNA. Translation: BAF85272.1.
RefSeqiNP_001268464.1. NM_001281535.1.
UniGeneiHs.213394.

Genome annotation databases

EnsembliENST00000545076; ENSP00000488626; ENSG00000082397.
GeneIDi23136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001032 Genomic DNA. No translation available.
AP005059 Genomic DNA. No translation available.
AP005671 Genomic DNA. No translation available.
AK292583 mRNA. Translation: BAF85272.1.
RefSeqiNP_001268464.1. NM_001281535.1.
UniGeneiHs.213394.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA8K968.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000545076; ENSP00000488626; ENSG00000082397.
GeneIDi23136.

Organism-specific databases

CTDi23136.
HGNCiHGNC:3380. EPB41L3.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118823.
HOGENOMiHOG000228840.
HOVERGENiHBG007777.

Miscellaneous databases

GenomeRNAii23136.
NextBioi35464617.

Gene expression databases

BgeeiA8K968.
ExpressionAtlasiA8K968. baseline and differential.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR030691. Band4.1-L3.
IPR008379. Band_4.1_C.
IPR019749. Band_41_domain.
IPR000798. Ez/rad/moesin-like.
IPR014847. FERM-adjacent.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR019747. FERM_CS.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR011993. PH_dom-like.
IPR007477. SAB_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR23280:SF20. PTHR23280:SF20. 1 hit.
PfamiPF05902. 4_1_CTD. 1 hit.
PF08736. FA. 1 hit.
PF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF04382. SAB. 1 hit.
[Graphical view]
PRINTSiPR00935. BAND41.
PR00661. ERMFAMILY.
SMARTiSM00295. B41. 1 hit.
SM01195. FA. 1 hit.
SM01196. FERM_C. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS00660. FERM_1. 1 hit.
PS00661. FERM_2. 1 hit.
PS50057. FERM_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  9. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. Ensembl
    Submitted (AUG-2015) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA8K968_HUMAN
AccessioniPrimary (citable) accession number: A8K968
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: May 11, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.