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A8K8Z4

- A8K8Z4_HUMAN

UniProt

A8K8Z4 - A8K8Z4_HUMAN

Protein
Submitted name:

cDNA FLJ78071, highly similar to Human MHC class III complement component C6 mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. immune response Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ78071, highly similar to Human MHC class III complement component C6 mRNAImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. membrane attack complex Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Proteomic databases

    PRIDEiA8K8Z4.

    Structurei

    3D structure databases

    ProteinModelPortaliA8K8Z4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG005366.

    Family and domain databases

    InterProiIPR003884. FacI_MAC.
    IPR002350. Kazal_dom.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR001862. MAC_perforin.
    IPR020864. MACPF.
    IPR020863. MACPF_CS.
    IPR000436. Sushi_SCR_CCP.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF07648. Kazal_2. 1 hit.
    PF00057. Ldl_recept_a. 1 hit.
    PF01823. MACPF. 1 hit.
    PF00084. Sushi. 2 hits.
    PF00090. TSP_1. 3 hits.
    [Graphical view]
    PRINTSiPR00764. COMPLEMENTC9.
    SMARTiSM00032. CCP. 2 hits.
    SM00057. FIMAC. 2 hits.
    SM00280. KAZAL. 1 hit.
    SM00192. LDLa. 1 hit.
    SM00457. MACPF. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view]
    SUPFAMiSSF57424. SSF57424. 1 hit.
    SSF57535. SSF57535. 2 hits.
    SSF82895. SSF82895. 3 hits.
    PROSITEiPS51465. KAZAL_2. 2 hits.
    PS01209. LDLRA_1. 1 hit.
    PS50068. LDLRA_2. 1 hit.
    PS00279. MACPF_1. 1 hit.
    PS51412. MACPF_2. 1 hit.
    PS50923. SUSHI. 2 hits.
    PS50092. TSP1. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A8K8Z4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARRSVLYFI LLNALINKGQ ACFCDHYAWT QWTSCSKTCN SGTQSRHRQI    50
    VVDKYYQENF CEQICSKQET RECNWQRCPI NCLLGDFGPW SDCDPCIEKQ 100
    SKVRSVLRPS QFGGQPCTEP LVAFQPCIPS KLCKIEEADC KNKFRCDSGR 150
    CIARKLECNG ENDCGDNSDE RDCGRTKAVC TRKYNPIPSV QLMGNGFHFL 200
    AGEPRGEVLD NSFTGGICKT VKSSRTSNPY RVPANLENVG FEVQTAEDDL 250
    KTDFYKDLTS LGHNENQQGS FSSQGGSSFS VPIFYSSKRS ENINHNSAFK 300
    QAIQASHKKD SSFIRIHKVM KVLNFTTKAK DLHLSDVFLK ALNHLPLEYN 350
    SALYSRIFDD FGTHYFTSGS LGGVYDLLYQ FSSEELKNSG LTEEEAKHCV 400
    RIETKKRVLF AKKTKVEHRC TTNKLSEKHE GSFIQGAEKS ISLIRGGRSE 450
    YGAALAWEKG SSGLEEKTFS EWLESVKENP AVIDFELAPI VDLVRNIPCA 500
    VTKRNNLRKA LQEYAAKFDP CQCAPCPNNG RPTLSGTECL CVCQSGTYGE 550
    NCEKQSPDYK SNAVDGQWGC WSSWSTCDAT YKRSRTRECN NPAPQRGGKR 600
    CEGEKRQEED CTFSIMENNG QPCINDDEEM KEVDLPEIEA DSGCPQPVPP 650
    ENGFIRNEKQ LYLVGEDVEI SCLTGFETVG YQYFRCLPDG TWRQGDVECQ 700
    RTECIKPVVQ EALTITPFQR LYRIGESIEL TCPKGFVVAG PSGYTCQGNS 750
    WTPPISNSLT CEKDTLTKLK GHCQLGQKQS GSECICMSPE EDCSHHSEDL 800
    CVFDTDSNDY FTSPACKFLA EKCLNNQQLH FLHIGSCQDG RQLEWGLERT 850
    RLSSNSTKKE SCGYDTCYDW EKCSASTSKC VCLLPPQCFK GGNQLYCVKM 900
    GSSTSEKTLN ICEVGTIRCA NRKMEILHPG KCLA 934
    Length:934
    Mass (Da):104,717
    Last modified:December 4, 2007 - v1
    Checksum:i85CFA95B89FB9F90
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK292509 mRNA. Translation: BAF85198.1.
    UniGeneiHs.481992.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK292509 mRNA. Translation: BAF85198.1 .
    UniGenei Hs.481992.

    3D structure databases

    ProteinModelPortali A8K8Z4.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A8K8Z4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG005366.

    Miscellaneous databases

    NextBioi 35464593.

    Family and domain databases

    InterProi IPR003884. FacI_MAC.
    IPR002350. Kazal_dom.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR001862. MAC_perforin.
    IPR020864. MACPF.
    IPR020863. MACPF_CS.
    IPR000436. Sushi_SCR_CCP.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF07648. Kazal_2. 1 hit.
    PF00057. Ldl_recept_a. 1 hit.
    PF01823. MACPF. 1 hit.
    PF00084. Sushi. 2 hits.
    PF00090. TSP_1. 3 hits.
    [Graphical view ]
    PRINTSi PR00764. COMPLEMENTC9.
    SMARTi SM00032. CCP. 2 hits.
    SM00057. FIMAC. 2 hits.
    SM00280. KAZAL. 1 hit.
    SM00192. LDLa. 1 hit.
    SM00457. MACPF. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view ]
    SUPFAMi SSF57424. SSF57424. 1 hit.
    SSF57535. SSF57535. 2 hits.
    SSF82895. SSF82895. 3 hits.
    PROSITEi PS51465. KAZAL_2. 2 hits.
    PS01209. LDLRA_1. 1 hit.
    PS50068. LDLRA_2. 1 hit.
    PS00279. MACPF_1. 1 hit.
    PS51412. MACPF_2. 1 hit.
    PS50923. SUSHI. 2 hits.
    PS50092. TSP1. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiA8K8Z4_HUMAN
    AccessioniPrimary (citable) accession number: A8K8Z4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 4, 2007
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.