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Protein
Submitted name:

Heat shock cognate 71 kDa protein

Gene

HSPA8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Heat shock cognate 71 kDa proteinImported
Submitted name:
cDNA FLJ77848Imported
Gene namesi
Name:HSPA8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000109971.13.
HGNCiHGNC:5241. HSPA8.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000109971.

PTM / Processingi

Proteomic databases

EPDiA8K7Q2.
MaxQBiA8K7Q2.

Expressioni

Gene expression databases

BgeeiENSG00000109971.
ExpressionAtlasiA8K7Q2. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiA8K7Q2. 8 interactors.

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili276 – 299Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
GeneTreeiENSGT00900000140908.
HOVERGENiHBG051845.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiView protein in InterPro
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C_sf.
IPR029047. HSP70_peptide-bd_sf.
IPR013126. Hsp_70_fam.
PfamiView protein in Pfam
PF00012. HSP70. 1 hit.
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiView protein in PROSITE
PS01036. HSP70_3. 1 hit.

Sequencei

Sequence statusi: Complete.

A8K7Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNHFIAEFK RKHKKDISEN KRAVRRLRTA CERAKRTLSS STQASIEIDS
60 70 80 90 100
LYEGIDFYTS ITRARFEELN ADLFRGTLDP VEKALRDAKL DKSQIHDIVL
110 120 130 140 150
VGGSTRIPKI QKLLQDFFNG KELNKSINPD EAVAYGAAVQ AAILSGDKSE
160 170 180 190 200
NVQDLLLLDV TPLSLGIETA GGVMTVLIKR NTTIPTKQTQ TFTTYSDNQP
210 220 230 240 250
GVLIQVYEGE RAMTKDNNLL GKFELTGIPP APRGVPQIEV TFDIDANGIL
260 270 280 290 300
NVSAVDKSTG KENKITITND KGRLSKEDIE RMVQEAEKYK AEDEKQRDKV
310 320 330 340 350
SSKNSLESYA FNMKATVEDE KLQGKINDED KQKILDKCNE IINWLDKNQT
360 370 380 390 400
AEKEEFEHQQ KELEKVCNPI ITKLYQSAGG MPGGMPGGFP GGGAPPSGGA
410
SSGPTIEEVD
Length:410
Mass (Da):45,338
Last modified:December 4, 2007 - v1
Checksum:i1BE1D9961D811469
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000926 Genomic DNA. No translation available.
AK292067 mRNA. Translation: BAF84756.1.
UniGeneiHs.180414.

Genome annotation databases

EnsembliENST00000534319; ENSP00000433316; ENSG00000109971.
UCSCiuc009zbc.4. human.

Similar proteinsi

Entry informationi

Entry nameiA8K7Q2_HUMAN
AccessioniPrimary (citable) accession number: A8K7Q2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: November 22, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported