A8K6K3 (A8K6K3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1, isoform CRA_f EMBL EAW60330.1

Submitted name:
cDNA FLJ78598, highly similar to Homo sapiens mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha, mRNA EMBL BAF84357.1
Submitted name:
cDNA, FLJ92811, Homo sapiens mitogen-activated protein kinase kinase kinase 7interacting protein 1 (MAP3K7IP1), mRNA EMBL BAG35363.1

Gene names

Name:	MAP3K7IP1 EMBL EAW60330.1
ORF Names:	hCG_41717 EMBL EAW60330.1

Organism

Homo sapiens (Human) EMBL BAF84357.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Kinase EMBL BAF84357.1 Transferase
Gene Ontology (GO)
Biological_process	activation of MAPKKK activity Inferred from electronic annotation. Source: Compara heart morphogenesis Inferred from electronic annotation. Source: Compara in utero embryonic development Inferred from electronic annotation. Source: Compara lung development Inferred from electronic annotation. Source: Compara transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: Compara
Molecular_function	kinase activator activity Inferred from electronic annotation. Source: Compara kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8K6K3 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: A45743288718983A	FASTA	504	54,644
	10 20 30 40 50 60 MAAQRRSLLQ SEQQPSWTDD LPLCHLSGVG SASNRSYSAD GKGTESHPPE DSWLKFRSEN 70 80 90 100 110 120 NCFLYGVFNG YDGNRVTNFV AQRLSAELLL GQLNAEHAEA DVRRVLLQAF DVVERSFLES 130 140 150 160 170 180 IDDALAEKAS LQSQLPEGVP QHQLPPQYQK ILERLKTLER EISGGAMAVV AVLLNNKLYV 190 200 210 220 230 240 ANVGTNRALL CKSTVDGLQV TQLNVDHTTE NEDELFRLSQ LGLDAGKIKQ VGIICGQEST 250 260 270 280 290 300 RRIGDYKVKY GYTDIDLLSA AKSKPIIAEP EIHGAQPLDG VTGFLVLMSE GLYKALEAAH 310 320 330 340 350 360 GPGQANQEIA AMIDTEFAKQ TSLDAVAQAV VDRVKRIHSD TFASGGERAR FCPRHEDMTL 370 380 390 400 410 420 LVRNFGYPLG EMSQPTPSPA PAAGGRVYPV SVPYSSAQST SKTSVTLSLV MPSQGQMVNG 430 440 450 460 470 480 AHSASTLDEA TPTLTNQSPT LTLQSTNTHT QSSSSSSDGG LFRSRPAHSL PPGEDGRVEP 490 500 YVDFAEFYRL WSVDHGEQSV VTAP

References

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL BAF84357.1.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Caudate nucleus EMBL BAG35363.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK291668 mRNA. Translation: BAF84357.1. AK312456 mRNA. Translation: BAG35363.1. CH471095 Genomic DNA. Translation: EAW60330.1.
IPI	IPI00019459.
RefSeq	NP_006107.1. NM_006116.2.
UniGene	Hs.507681.
3D structure databases
ProteinModelPortal	A8K6K3.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000216160. A8K6K3.
Proteomic databases
PRIDE	A8K6K3.
Protocols and materials databases
DNASU	10454.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10454.
KEGG	hsa:10454.
Organism-specific databases
CTD	10454.
PharmGKB	PA30604.
Phylogenomic databases
HOVERGEN	HBG007302.
KO	K04403.
OMA	AEHTEAD.
PhylomeDB	A8K6K3.
Gene expression databases
ArrayExpress	A8K6K3.
Bgee	A8K6K3.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	10454.
NextBio	39627.

Entry information

Entry name

A8K6K3_HUMAN

Accession

Primary (citable) accession number: A8K6K3

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	May 1, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.