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Protein
Submitted name:

Chorionic somatomammotropin hormone 1 isoform 1

Gene

GHB3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHormoneUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Chorionic somatomammotropin hormone 1 isoform 1Imported
Submitted name:
Growth hormone B3Imported
Submitted name:
HCG1749481, isoform CRA_cImported
Submitted name:
HCG1749481, isoform CRA_eImported
Submitted name:
HCG1749481, isoform CRA_iImported
Submitted name:
cDNA FLJ75407, highly similar to Homo sapiens chorionic somatomammotropin hormone 1 (placental lactogen) (CSH1), transcript variant 1, mRNAImported
Gene namesi
Name:GHB3Imported
Synonyms:CSH1Imported
ORF Names:hCG_1749481Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000136488.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26943

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_501429754227 – 217Sequence analysisAdd BLAST191

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000136488

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFR6 Eukaryota
ENOG4111HU8 LUCA
HOVERGENiHBG011318
KOiK05438
OMAiHSIMENP

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR001400 Somatotropin/Prolactin
IPR018116 Somatotropin_CS
PANTHERiPTHR11417 PTHR11417, 1 hit
PfamiView protein in Pfam
PF00103 Hormone_1, 1 hit
PRINTSiPR00836 SOMATOTROPIN
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00266 SOMATOTROPIN_1, 1 hit
PS00338 SOMATOTROPIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8K6C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPGSRTSLL LAFALLCLPW LQEAGAVQTV PLSRLFDHAM LQAHRAHQLA
60 70 80 90 100
IDTYQEFEET YIPKDQKYSF LHDSQTSFCF SDSIPTPSNM EETQQKSNLE
110 120 130 140 150
LLRISLLLIE SWLEPVRFLR SMFANNLVYD TSDSDDYHLL KDLEEGIQTL
160 170 180 190 200
MGRLEDGSRR TGQILKQTYS KFDTNSHNHD ALLKNYGLLY CFRKDMDKVE
210
TFLRMVQCRS VEGSCGF
Length:217
Mass (Da):25,020
Last modified:December 4, 2007 - v1
Checksum:i235B0DC7A713F431
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei217Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU421714 Genomic DNA Translation: ABZ88716.1
AK291587 mRNA Translation: BAF84276.1
LM644138 mRNA Translation: CDW51385.1
CH471109 Genomic DNA Translation: EAW94235.1
CH471109 Genomic DNA Translation: EAW94237.1
CH471109 Genomic DNA Translation: EAW94241.1
RefSeqiNP_001308.1, NM_001317.5
UniGeneiHs.654390

Genome annotation databases

GeneIDi1442
KEGGihsa:1442

Similar proteinsi

Entry informationi

Entry nameiA8K6C2_HUMAN
AccessioniPrimary (citable) accession number: A8K6C2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 25, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health