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Protein
Submitted name:

Epididymis secretory protein Li 103

Gene

HSPA1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processStress responseImported
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Epididymis secretory protein Li 103Imported
Submitted name:
HSPA1AImported
Submitted name:
HSPA1BImported
Submitted name:
Heat shock 70kDa protein 1AImported
Submitted name:
Heat shock 70kDa protein 1BImported
Submitted name:
cDNA FLJ75127, highly similar to Homo sapiens heat shock 70kDa protein 1A, mRNAImported
Gene namesi
Name:HSPA1BImported
Synonyms:HEL-S-103Imported, HSPA1AImported
ORF Names:hCG_1820593Imported, hCG_43726Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000204388.6
HostDB:ENSG00000204389.9

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29499

Expressioni

Gene expression databases

BgeeiENSG00000204388

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili512 – 535Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0101 Eukaryota
COG0443 LUCA
HOVERGENiHBG051845
KOiK03283
OMAiTHRTRVE
OrthoDBiEOG093705LK

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
InterProiView protein in InterPro
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

A8K5I0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKAAAIGID LGTTYSCVGV FQHGKVEIIA NDQGNRTTPS YVAFTDTERL
60 70 80 90 100
IGDAAKNQVA LNPQNTVFDA KRLIGRKFGD PVVQSDMKHW PFQVINDGDK
110 120 130 140 150
PKVQVSYKGE TKAFYPEEIS SMVLTKMKEI AEAYLGYPVT NAVITVPAYF
160 170 180 190 200
NDSQRQATKD AGVIAGLNVL RIINEPTAAA IAYGLDRTGK GERNVLIFDL
210 220 230 240 250
GGGTFDVSIL TIDDGIFEVK ATAGDTHLGG EDFDNRLVNH FVEEFKRKHK
260 270 280 290 300
KDISQNKRAV RRLRTACERA KRTLSSSTQA SLEIDSLFEG IDFYTSITRA
310 320 330 340 350
RFEELCSDLF RSTLEPVEKA LRDAKLDKAQ IHDLVLVGGS TRIPKVQKLL
360 370 380 390 400
QDFFNGRDLN KSINPDEAVA YGAAVQAAIL MGDKSENVQD LLLLDVAPLS
410 420 430 440 450
LGLETAGGVM TALIKRNSTI PTKQTQIFTT YSDNQPGVLI QVYEGERAMT
460 470 480 490 500
KDNNLLGRFE LSGIPPAPRG VPQIEVTFDI DANGILNVTA TDKSTGKANK
510 520 530 540 550
ITITNDKGRL SKEEIERMVQ EAEKYKAEDE VQRERVSAKN ALESYAFNMK
560 570 580 590 600
SAVEDEGLKG KISEADKKKV LDKCQEVISW LDANTLAEKD EFEHKRKELE
610 620 630 640
QVCNPIISGL YQGAGGPGPG GFGAQGPKGG SGSGPTIEEV D
Length:641
Mass (Da):70,052
Last modified:December 4, 2007 - v1
Checksum:i78F513118C96DE66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ224292 mRNA Translation: ACI45984.1
KY500377 Genomic DNA Translation: AQY76864.1
KY500378 Genomic DNA Translation: AQY76865.1
KY500379 Genomic DNA Translation: AQY76866.1
KY500381 Genomic DNA Translation: AQY76868.1
KY500382 Genomic DNA Translation: AQY76869.1
KY500383 Genomic DNA Translation: AQY76870.1
KY500384 Genomic DNA Translation: AQY76871.1
KY500387 Genomic DNA Translation: AQY76874.1
KY500388 Genomic DNA Translation: AQY76875.1
KY500389 Genomic DNA Translation: AQY76876.1
KY500390 Genomic DNA Translation: AQY76877.1
KY500392 Genomic DNA Translation: AQY76879.1
KY500393 Genomic DNA Translation: AQY76880.1
KY500394 Genomic DNA Translation: AQY76881.1
KY500395 Genomic DNA Translation: AQY76882.1
KY500396 Genomic DNA Translation: AQY76883.1
KY500397 Genomic DNA Translation: AQY76884.1
AK291295 mRNA Translation: BAF83984.1
CH471081 Genomic DNA Translation: EAX03528.1
CH471081 Genomic DNA Translation: EAX03529.1
RefSeqiNP_005336.3, NM_005345.5
NP_005337.2, NM_005346.4
UniGeneiHs.274402
Hs.702139
Hs.719966
Hs.743411

Genome annotation databases

GeneIDi3303
3304
KEGGihsa:3303
hsa:3304

Similar proteinsi

Entry informationi

Entry nameiA8K5I0_HUMAN
AccessioniPrimary (citable) accession number: A8K5I0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 25, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health