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Protein
Submitted name:

cDNA FLJ78736, highly similar to Homo sapiens phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ78736, highly similar to Homo sapiens phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 2, mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

GenevisibleiA8K460. HS.

Structurei

3D structure databases

ProteinModelPortaliA8K460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 6 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, RepeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000013092.
HOVERGENiHBG053482.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR002641. Patatin/PLipase_A2-rel.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01734. Patatin. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF52151. SSF52151. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFFGRLVNT FSGVTNLFSN PFRVKEVAVA DYTSSDRVRE EGQLILFQNT
60 70 80 90 100
PNRTWDCVLV NPRNSQSGFR LFQLELEADA LVNFHQYSSQ LLPFYESSPQ
110 120 130 140 150
VLHTEVLQHL TDLIRNHPSW SVPHLAVELG IRECFHHSRI ISCANCAENE
160 170 180 190 200
EGCTPLHLAC RKGDGEILVE LVQYCHTQMD VTDYKGETVF HYAVQGDNSQ
210 220 230 240 250
VLQLLGRNAV AGLNQVNNQG LTPLHLACQL GKQEMVRVLL LCNARCNIMG
260 270 280 290 300
PNGYPIHSAM KFSQKGCAEM IISMDSSQIH SKDPRYGASP LHWAKNAEMA
310 320 330 340 350
RMLLKRGCNV NSTSSAGSTA LHVAVMRNRF DCAIVLLTHG ANADARGEHG
360 370 380 390 400
NTPLHLAMSK DNVEMIKALI VFGAEVDTPN DFGETPTFLA SKIGRQLQDL
410 420 430 440 450
MHISRARKPA FILGSMRDEK RTHDHLLCLD GGGVKGLIII QLLIAIEKAS
460 470 480 490 500
GVATKDLFDW VAGTSTGGIL ALAILHSKSM AYMRGMYFRM KDEVFRGSRP
510 520 530 540 550
YESGPLEEFL KREFGEHTKM TDVRKPKVML TGTLSDRQPA ELHLFRNYDA
560 570 580 590 600
PETVREPRFN QNVNLRPPAQ PSDQLVWRAA RSSGAAPTYF RPNGRFLDGG
610 620 630 640 650
LLANNPTLDA MTEIHEYNQD LIRKGQANKV KKLSIVVSLG TGRSPQVPVT
660 670 680 690 700
CVDVFRPSNP WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG
710 720 730 740 750
IQYFRLNPQL GTDIMLDEVS DTVLVNALWE TEVYIYEHRE EFQKLIQLLL

SP
Length:752
Mass (Da):84,092
Last modified:December 4, 2007 - v1
Checksum:i129099FF946D0D18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290825 mRNA. Translation: BAF83514.1.
RefSeqiNP_001186491.1. NM_001199562.1.
UniGeneiHs.170479.

Genome annotation databases

GeneIDi8398.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290825 mRNA. Translation: BAF83514.1.
RefSeqiNP_001186491.1. NM_001199562.1.
UniGeneiHs.170479.

3D structure databases

ProteinModelPortaliA8K460.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi8398.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8398.

Organism-specific databases

CTDi8398.

Phylogenomic databases

HOGENOMiHOG000013092.
HOVERGENiHBG053482.

Miscellaneous databases

GenomeRNAii8398.
NextBioi31428.

Gene expression databases

GenevisibleiA8K460. HS.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR002641. Patatin/PLipase_A2-rel.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
PF01734. Patatin. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
SSF52151. SSF52151. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LiverImported.

Entry informationi

Entry nameiA8K460_HUMAN
AccessioniPrimary (citable) accession number: A8K460
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: July 22, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.