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A8K460 (A8K460_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
OrganismHomo sapiens (Human) EMBL BAF83514.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length752 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 6 ANK repeats. RuleBase RU003321

Contains patatin domain. SAAS SAAS016035

Ontologies

Keywords
   DomainANK repeat RuleBase RU003321
Repeat RuleBase RU003536
Gene Ontology (GO)
   Biological_processlipid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionhydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A8K460 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 129099FF946D0D18

FASTA75284,092
        10         20         30         40         50         60 
MQFFGRLVNT FSGVTNLFSN PFRVKEVAVA DYTSSDRVRE EGQLILFQNT PNRTWDCVLV 

        70         80         90        100        110        120 
NPRNSQSGFR LFQLELEADA LVNFHQYSSQ LLPFYESSPQ VLHTEVLQHL TDLIRNHPSW 

       130        140        150        160        170        180 
SVPHLAVELG IRECFHHSRI ISCANCAENE EGCTPLHLAC RKGDGEILVE LVQYCHTQMD 

       190        200        210        220        230        240 
VTDYKGETVF HYAVQGDNSQ VLQLLGRNAV AGLNQVNNQG LTPLHLACQL GKQEMVRVLL 

       250        260        270        280        290        300 
LCNARCNIMG PNGYPIHSAM KFSQKGCAEM IISMDSSQIH SKDPRYGASP LHWAKNAEMA 

       310        320        330        340        350        360 
RMLLKRGCNV NSTSSAGSTA LHVAVMRNRF DCAIVLLTHG ANADARGEHG NTPLHLAMSK 

       370        380        390        400        410        420 
DNVEMIKALI VFGAEVDTPN DFGETPTFLA SKIGRQLQDL MHISRARKPA FILGSMRDEK 

       430        440        450        460        470        480 
RTHDHLLCLD GGGVKGLIII QLLIAIEKAS GVATKDLFDW VAGTSTGGIL ALAILHSKSM 

       490        500        510        520        530        540 
AYMRGMYFRM KDEVFRGSRP YESGPLEEFL KREFGEHTKM TDVRKPKVML TGTLSDRQPA 

       550        560        570        580        590        600 
ELHLFRNYDA PETVREPRFN QNVNLRPPAQ PSDQLVWRAA RSSGAAPTYF RPNGRFLDGG 

       610        620        630        640        650        660 
LLANNPTLDA MTEIHEYNQD LIRKGQANKV KKLSIVVSLG TGRSPQVPVT CVDVFRPSNP 

       670        680        690        700        710        720 
WELAKTVFGA KELGKMVVDC CTDPDGRAVD RARAWCEMVG IQYFRLNPQL GTDIMLDEVS 

       730        740        750 
DTVLVNALWE TEVYIYEHRE EFQKLIQLLL SP 

« Hide

References

[1]"NEDO human cDNA sequencing project."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Liver EMBL BAF83514.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK290825 mRNA. Translation: BAF83514.1.
RefSeqNP_001186491.1. NM_001199562.1.
UniGeneHs.170479.

3D structure databases

ProteinModelPortalA8K460.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

DNASU8398.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8398.
KEGGhsa:8398.

Organism-specific databases

CTD8398.

Phylogenomic databases

HOGENOMHOG000013092.
HOVERGENHBG053482.
KOK16343.

Family and domain databases

Gene3D1.25.40.20. 2 hits.
InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR002641. Patatin/PLipase_A2-rel.
[Graphical view]
PfamPF12796. Ank_2. 1 hit.
PF01734. Patatin. 1 hit.
[Graphical view]
PRINTSPR01415. ANKYRIN.
SMARTSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
SSF52151. SSF52151. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi8398.
NextBio31428.

Entry information

Entry nameA8K460_HUMAN
AccessionPrimary (citable) accession number: A8K460
Entry history
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.