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Protein
Submitted name:

Prohibitin, isoform CRA_a

Gene

PHB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Prohibitin, isoform CRA_aImported
Submitted name:
cDNA FLJ78511, highly similar to Homo sapiens prohibitin (PHB), mRNAImported
Submitted name:
cDNA, FLJ93035, Homo sapiens prohibitin (PHB), mRNAImported
Gene namesi
Name:PHBImported
ORF Names:hCG_29613Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33251.

Expressioni

Gene expression databases

BgeeiENSG00000167085.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000300408.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 187PHBInterPro annotationAdd BLAST162

Phylogenomic databases

eggNOGiKOG3083. Eukaryota.
COG0330. LUCA.
HOVERGENiHBG004457.
KOiK17080.
OMAiTMANEKQ.
OrthoDBiEOG091G0IHW.

Family and domain databases

CDDicd03401. SPFH_prohibitin. 1 hit.
InterProiIPR001107. Band_7.
IPR000163. Prohibitin.
[Graphical view]
PANTHERiPTHR23222. PTHR23222. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PRINTSiPR00679. PROHIBITIN.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.

Sequencei

Sequence statusi: Complete.

A8K401-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKVFESIG KFGLALAVAG GVVNSALYNV DAGHRAVIFD RFRGVQDIVV
60 70 80 90 100
GEGTHFLIPW VQKPIIFDCR SRPRNVPVIT GSKDLQNVNI TLRILFRPVA
110 120 130 140 150
SQLPRIFTSI GEDYDERVLP SITTEILKSV VARFDAGELI TQRELVSRQV
160 170 180 190 200
SDDLTERAAT FGLILDDVSL THLTFGKEFT EAVEAKQVAQ QEAERARFVV
210 220 230 240 250
EKAEQQKKAA IISAEGDSKA AELIANSLAT AGDGLIELRK LEAAEDIAYQ
260 270
LSRSRNITYL PAGQSVLLQL PQ
Length:272
Mass (Da):29,804
Last modified:December 4, 2007 - v1
Checksum:i915494273E342C76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290766 mRNA. Translation: BAF83455.1.
AK312649 mRNA. Translation: BAG35532.1.
CH471109 Genomic DNA. Translation: EAW94680.1.
CH471109 Genomic DNA. Translation: EAW94681.1.
RefSeqiNP_001268425.1. NM_001281496.1.
NP_001268644.1. NM_001281715.1.
NP_002625.1. NM_002634.3.
XP_016880252.1. XM_017024763.1.
UniGeneiHs.514303.

Genome annotation databases

GeneIDi5245.
KEGGihsa:5245.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290766 mRNA. Translation: BAF83455.1.
AK312649 mRNA. Translation: BAG35532.1.
CH471109 Genomic DNA. Translation: EAW94680.1.
CH471109 Genomic DNA. Translation: EAW94681.1.
RefSeqiNP_001268425.1. NM_001281496.1.
NP_001268644.1. NM_001281715.1.
NP_002625.1. NM_002634.3.
XP_016880252.1. XM_017024763.1.
UniGeneiHs.514303.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000300408.

Protocols and materials databases

DNASUi5245.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5245.
KEGGihsa:5245.

Organism-specific databases

CTDi5245.
PharmGKBiPA33251.

Phylogenomic databases

eggNOGiKOG3083. Eukaryota.
COG0330. LUCA.
HOVERGENiHBG004457.
KOiK17080.
OMAiTMANEKQ.
OrthoDBiEOG091G0IHW.

Miscellaneous databases

GenomeRNAii5245.

Gene expression databases

BgeeiENSG00000167085.

Family and domain databases

CDDicd03401. SPFH_prohibitin. 1 hit.
InterProiIPR001107. Band_7.
IPR000163. Prohibitin.
[Graphical view]
PANTHERiPTHR23222. PTHR23222. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PRINTSiPR00679. PROHIBITIN.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA8K401_HUMAN
AccessioniPrimary (citable) accession number: A8K401
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: November 2, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.