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Protein
Submitted name:

cDNA FLJ75284, highly similar to Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ75284, highly similar to Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiA8K3R3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 47A20-typeInterPro annotationAdd BLAST35
Domaini232 – 375VPS9InterPro annotationAdd BLAST144

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili414 – 437Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2319. Eukaryota.
KOG3173. Eukaryota.
ENOG410YGAZ. LUCA.
HOGENOMiHOG000070180.
HOVERGENiHBG062584.

Family and domain databases

InterProiView protein in InterPro
IPR003123. VPS9.
IPR037191. VPS9_dom_sf.
IPR002653. Znf_A20.
PfamiView protein in Pfam
PF02204. VPS9. 1 hit.
PF01754. zf-A20. 1 hit.
SMARTiView protein in SMART
SM00167. VPS9. 1 hit.
SM00259. ZnF_A20. 1 hit.
SUPFAMiSSF109993. SSF109993. 1 hit.
PROSITEiView protein in PROSITE
PS51205. VPS9. 1 hit.
PS51036. ZF_A20. 1 hit.

Sequencei

Sequence statusi: Complete.

A8K3R3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ
60 70 80 90 100
IQEDWELAER LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT
110 120 130 140 150
VKKFFSASSR VGSKKEIQEA KAPSPSINRQ TSIETDRVSK EFIEFLKTFH
160 170 180 190 200
KTGQEIYKQT KLFLEGMHYK RDLSIEEQSE CAQDFYHNVA ERMQTRGKVP
210 220 230 240 250
PERVEKIMDQ IEKYIMTRLY KYVFCPGTTD DEKKDLAIQK RIRALRWVTP
260 270 280 290 300
QMLCVPVNED IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITKCSKHIFN
310 320 330 340 350
AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG
360 370 380 390 400
EDGYYFTNLC CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQEAESWS
410 420 430 440 450
PDACLGVKQM YKNLDLLSQL NERQERIMNE AKKLEKDLID WTDGIAREVQ
460 470 480 490
DIVEKYPLEI KPPNQPLAAI DSENVENDKL PPPLQPQVYA G
Length:491
Mass (Da):56,819
Last modified:December 4, 2007 - v1
Checksum:i490689A277DABE91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290678 mRNA. Translation: BAF83367.1.
RefSeqiNP_001273991.1. NM_001287062.1.
UniGeneiHs.530053.
Hs.662268.
Hs.733181.

Genome annotation databases

GeneIDi27342.

Similar proteinsi

Entry informationi

Entry nameiA8K3R3_HUMAN
AccessioniPrimary (citable) accession number: A8K3R3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: January 31, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.