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A8K3F7

- A8K3F7_HUMAN

UniProt

A8K3F7 - A8K3F7_HUMAN

Protein
Submitted name:

Interleukin 11

Gene

IL11

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (04 Dec 2007)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. positive regulation of cell proliferation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Interleukin 11Imported
    Submitted name:
    cDNA FLJ78117, highly similar to Homo sapiens interleukin 11 (IL11), mRNAImported
    Submitted name:
    cDNA, FLJ96313, Homo sapiens interleukin 11 (IL11), mRNAImported
    Gene namesi
    Name:IL11Imported
    ORF Names:hCG_37996Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA29781.

    Structurei

    3D structure databases

    SMRiA8K3F7. Positions 40-195.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG003999.
    KOiK05417.
    OMAiMNSVCCL.
    PhylomeDBiA8K3F7.

    Family and domain databases

    InterProiIPR009079. 4_helix_cytokine-like_core.
    IPR020438. IL-11.
    IPR020412. IL-11_mml.
    [Graphical view]
    PfamiPF07400. IL11. 1 hit.
    [Graphical view]
    PRINTSiPR01943. INTLKN11MAML.
    PR01927. INTRLEUKIN11.
    SUPFAMiSSF47266. SSF47266. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A8K3F7-1 [UniParc]FASTAAdd to Basket

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    MNCVCRLVLV VLSLWPDTAV APGPPPGPPR VSPDPRAELD STVLLTRSLL    50
    ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD 100
    LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP 150
    QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL 199
    Length:199
    Mass (Da):21,429
    Last modified:December 4, 2007 - v1
    Checksum:iF292BF8B34F4096D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK290572 mRNA. Translation: BAF83261.1.
    AK315294 mRNA. Translation: BAG37700.1.
    CH471135 Genomic DNA. Translation: EAW72371.1.
    RefSeqiNP_000632.1. NM_000641.3.
    UniGeneiHs.467304.

    Genome annotation databases

    GeneIDi3589.
    KEGGihsa:3589.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK290572 mRNA. Translation: BAF83261.1 .
    AK315294 mRNA. Translation: BAG37700.1 .
    CH471135 Genomic DNA. Translation: EAW72371.1 .
    RefSeqi NP_000632.1. NM_000641.3.
    UniGenei Hs.467304.

    3D structure databases

    SMRi A8K3F7. Positions 40-195.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 3589.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3589.
    KEGGi hsa:3589.

    Organism-specific databases

    CTDi 3589.
    PharmGKBi PA29781.

    Phylogenomic databases

    HOVERGENi HBG003999.
    KOi K05417.
    OMAi MNSVCCL.
    PhylomeDBi A8K3F7.

    Miscellaneous databases

    GenomeRNAii 3589.
    NextBioi 14023.

    Family and domain databases

    InterProi IPR009079. 4_helix_cytokine-like_core.
    IPR020438. IL-11.
    IPR020412. IL-11_mml.
    [Graphical view ]
    Pfami PF07400. IL11. 1 hit.
    [Graphical view ]
    PRINTSi PR01943. INTLKN11MAML.
    PR01927. INTRLEUKIN11.
    SUPFAMi SSF47266. SSF47266. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE.
    4. "NEDO functional analysis of protein and research application project."
      Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
      Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiA8K3F7_HUMAN
    AccessioniPrimary (citable) accession number: A8K3F7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 4, 2007
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.