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Protein
Submitted name:

Interleukin 11

Gene

IL11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 11Imported
Submitted name:
cDNA FLJ78117, highly similar to Homo sapiens interleukin 11 (IL11), mRNAImported
Submitted name:
cDNA, FLJ96313, Homo sapiens interleukin 11 (IL11), mRNAImported
Gene namesi
Name:IL11Imported
ORF Names:hCG_37996Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000095752.6.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29781.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501010406722 – 199Sequence analysisAdd BLAST178

Expressioni

Gene expression databases

BgeeiENSG00000095752.
ExpressionAtlasiA8K3F7. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA8K3F7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IWMH. Eukaryota.
ENOG411181Z. LUCA.
HOVERGENiHBG003999.
KOiK05417.
OMAiMNSVCCL.
OrthoDBiEOG091G0V1V.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR020438. IL-11.
IPR020412. IL-11_mml.
PfamiView protein in Pfam
PF07400. IL11. 1 hit.
PRINTSiPR01943. INTLKN11MAML.
PR01927. INTRLEUKIN11.
SUPFAMiSSF47266. SSF47266. 1 hit.

Sequencei

Sequence statusi: Complete.

A8K3F7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNCVCRLVLV VLSLWPDTAV APGPPPGPPR VSPDPRAELD STVLLTRSLL
60 70 80 90 100
ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD
110 120 130 140 150
LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP
160 170 180 190
QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Length:199
Mass (Da):21,429
Last modified:December 4, 2007 - v1
Checksum:iF292BF8B34F4096D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290572 mRNA. Translation: BAF83261.1.
AK315294 mRNA. Translation: BAG37700.1.
CH471135 Genomic DNA. Translation: EAW72371.1.
RefSeqiNP_000632.1. NM_000641.3.
UniGeneiHs.467304.

Genome annotation databases

GeneIDi3589.
KEGGihsa:3589.

Similar proteinsi

Entry informationi

Entry nameiA8K3F7_HUMAN
AccessioniPrimary (citable) accession number: A8K3F7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: September 27, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.