A8K3E0 (A8K3E0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nuclear factor (Erythroid-derived 2), 45kDa, isoform CRA_a EMBL EAW96771.1

Submitted name:
cDNA FLJ78141, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein EMBL BAF83253.1
Submitted name:
cDNA FLJ78153, highly similar to nuclear factor erythroid 2 isoform f=basic leucine zipper protein EMBL BAF83244.1
Submitted name:
cDNA, FLJ93708, Homo sapiens nuclear factor (erythroid-derived 2), 45kDa (NFE2),mRNA EMBL BAG36023.1

Gene names

Name:	NFE2 EMBL EAW96771.1
ORF Names:	hCG_37258 EMBL EAW96771.1

Organism

Homo sapiens (Human) EMBL BAF83244.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	DNA-binding SAAS SAAS004827
Gene Ontology (GO)
Biological_process	cell-cell signaling Inferred from electronic annotation. Source: Compara negative regulation of bone mineralization Inferred from electronic annotation. Source: Compara
Cellular_component	actin cytoskeleton Inferred from direct assay. Source: HPA nucleus Inferred from direct assay. Source: HPA
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8K3E0 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: A9821170FB2ED67C	FASTA	373	41,473
	10 20 30 40 50 60 MSPCPPQQSR NRVIQLSTSE LGEMELTWQE IMSITELQGL NAPSEPSFEP QAPAPYLGPP 70 80 90 100 110 120 PPTTYCPCSI HPDSGFPLPP PPYELPASTS HVPDPPYSYG NMAIPVSKPL SLSGLLSEPL 130 140 150 160 170 180 QDPLALLDIG LPAGPPKPQE DPESDSGLSL NYSDAESLEL EGTEAGRRRS EYVEMYPVEY 190 200 210 220 230 240 PYSLMPNSLA HSNYTLPAAE TPLALEPSSG PVRAKPTARG EAGSRDERRA LAMKIPFPTD 250 260 270 280 290 300 KIVNLPVDDF NELLARYPLT ESQLALVRDI RRRGKNKVAA QNCRKRKLET IVQLERELER 310 320 330 340 350 360 LTNERERLLR ARGEADRTLE VMRQQLTELY RDIFQHLRDE SGNSYSPEEY ALQQAADGTI 370 FLVPRGTKME ATD

References

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Heart EMBL BAF83244.1 and Liver EMBL BAF83253.1.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK290555 mRNA. Translation: BAF83244.1. AK290564 mRNA. Translation: BAF83253.1. AK313207 mRNA. Translation: BAG36023.1. CH471054 Genomic DNA. Translation: EAW96771.1.
IPI	IPI00003367.
RefSeq	NP_001129495.1. NM_001136023.2. NP_001248390.1. NM_001261461.1. NP_006154.1. NM_006163.2.
UniGene	Hs.75643.
3D structure databases
ModBase	Search...
Protocols and materials databases
DNASU	4778.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4778.
KEGG	hsa:4778.
Organism-specific databases
CTD	4778.
PharmGKB	PA31586.
Phylogenomic databases
HOVERGEN	HBG002901.
KO	K09039.
OMA	LETIVQL.
Family and domain databases
Gene3D	1.10.880.10. 1 hit.
InterPro	IPR004827. bZIP. IPR008917. Euk_TF_DNA-bd. [Graphical view]
Pfam	PF00170. bZIP_1. 1 hit. [Graphical view]
SMART	SM00338. BRLZ. 1 hit. [Graphical view]
SUPFAM	SSF47454. Euk_transcr_DNA. 1 hit.
PROSITE	PS50217. BZIP. 1 hit. PS00036. BZIP_BASIC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	4778.
NextBio	18424.

Entry information

Entry name

A8K3E0_HUMAN

Accession

Primary (citable) accession number: A8K3E0

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.