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Protein
Submitted name:

cDNA FLJ75083, highly similar to Homo sapiens amine oxidase (flavin containing) domain 2 (AOF2),mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi159 – 18729FADUniRule annotationAdd
BLAST
Nucleotide bindingi210 – 2112FADUniRule annotation
Nucleotide bindingi688 – 6892FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

FADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ75083, highly similar to Homo sapiens amine oxidase (flavin containing) domain 2 (AOF2),mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA8K2R3.
PeptideAtlasiA8K2R3.
PRIDEiA8K2R3.

Interactioni

Protein-protein interaction databases

IntActiA8K2R3. 8 interactions.
STRINGi9606.ENSP00000383042.

Structurei

3D structure databases

ProteinModelPortaliA8K2R3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini52 – 151100SWIRMInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili312 – 34635Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains SWIRM domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0029. Eukaryota.
KOG0685. Eukaryota.
ENOG410XSNC. LUCA.
HOVERGENiHBG102081.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR017366. Hist_Lys-spec_deMease.
IPR009057. Homeodomain-like.
IPR007526. SWIRM.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
PF04433. SWIRM. 1 hit.
[Graphical view]
PIRSFiPIRSF038051. Histone_Lys-demethylase. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51905. SSF51905. 3 hits.
PROSITEiPS50934. SWIRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K2R3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDESLANLSE DEYYSEEERN AKAEKEKKLP PPPPQAPPEE ENESEPEEPS
60 70 80 90 100
GVEGAAFQSR LPHDRMTSQE AACFPDIISG PQQTQKVFLF IRNRTLQLWL
110 120 130 140 150
DNPKIQLTFE ATLQQLEAPY NSDTVLVHRV HSYLERHGLI NFGIYKRIKP
160 170 180 190 200
LPTKKTGKVI IIGSGVSGLA AARQLQSFGM DVTLLEARDR VGGRVATFRK
210 220 230 240 250
GNYVADLGAM VVTGLGGNPM AVVSKQVNME LAKIKQKCPP YEANGQAVPK
260 270 280 290 300
EKDEMVEQEF NRLLEATSYL SHQLDFNVLN NKPVSLGQAL EVVIQLQEKH
310 320 330 340 350
VKDEQIEHWK KIVKTQEELK ELLNKMVNLK EKIKELHQQY KEASEVKPPR
360 370 380 390 400
DITAEFLVKS KHRDLTALCK EYDELAETQG KLEEKLQELE ANPPSDVYLS
410 420 430 440 450
SRDRQILDWH FANLEFANAT PLSTLSLKHW DQDDDFEFTG SHLTVRNGYS
460 470 480 490 500
CVPVALAEGL DIKLNTAVRQ VRYTASGCEV IAVNTRSTSQ TFIYKCDAVL
510 520 530 540 550
CTLPLGVLKQ QPPAVQFVPP LPEWKTSAVQ RMGFGNLNKV VLCFDRVFWD
560 570 580 590 600
PSVNLFGHVG STTASRGELF LFWNLYKAPI LLALVAGEAA GIMENISDDV
610 620 630 640 650
IVGRCLAILK GIFGSSAVPQ PKETVVSRWR ADPWARGSYS YVAAGSSGND
660 670 680 690 700
YDLMAQPITP GPSIPGAPQP IPRLFFAGEH TIRNYPATVH GALLSGLREA
710 720 730
GRIADQFLGA MYTLPRQATP GVPAQQSPSM
Length:730
Mass (Da):81,170
Last modified:December 4, 2007 - v1
Checksum:i079C379B1FFBED3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290328 mRNA. Translation: BAF83017.1.
UniGeneiHs.591518.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290328 mRNA. Translation: BAF83017.1.
UniGeneiHs.591518.

3D structure databases

ProteinModelPortaliA8K2R3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA8K2R3. 8 interactions.
STRINGi9606.ENSP00000383042.

Proteomic databases

PaxDbiA8K2R3.
PeptideAtlasiA8K2R3.
PRIDEiA8K2R3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0029. Eukaryota.
KOG0685. Eukaryota.
ENOG410XSNC. LUCA.
HOVERGENiHBG102081.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR017366. Hist_Lys-spec_deMease.
IPR009057. Homeodomain-like.
IPR007526. SWIRM.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01593. Amino_oxidase. 1 hit.
PF04433. SWIRM. 1 hit.
[Graphical view]
PIRSFiPIRSF038051. Histone_Lys-demethylase. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51905. SSF51905. 3 hits.
PROSITEiPS50934. SWIRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TongueImported.

Entry informationi

Entry nameiA8K2R3_HUMAN
AccessioniPrimary (citable) accession number: A8K2R3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: July 6, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.