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Protein
Submitted name:

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, isoform CRA_b

Gene

GNAL

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type, isoform CRA_bImported
Submitted name:
cDNA FLJ78702, highly similar to Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type (GNAL), transcript variant 2, mRNAImported
Submitted name:
cDNA, FLJ94539, Homo sapiens guanine nucleotide binding protein (G protein), alphaactivating activity polypeptide, olfactory type (GNAL), transcriptvariant 2, mRNAImported
Gene namesi
Name:GNALImported
ORF Names:hCG_1780858Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000141404.15.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28770.

Expressioni

Gene expression databases

BgeeiENSG00000141404.
ExpressionAtlasiA8K1Y9. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA8K1Y9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0099. Eukaryota.
ENOG410XPC4. LUCA.
HOVERGENiHBG063184.
KOiK04633.
OMAiQENRATC.

Family and domain databases

CDDicd00066. G-alpha. 1 hit.
Gene3Di1.10.400.10. 1 hit.
InterProiView protein in InterPro
IPR000367. Gprotein_alpha_S.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
PANTHERiPTHR10218. PTHR10218. 1 hit.
PfamiView protein in Pfam
PF00503. G-alpha. 1 hit.
PRINTSiPR00318. GPROTEINA.
PR00443. GPROTEINAS.
SMARTiView protein in SMART
SM00275. G_alpha. 1 hit.
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

A8K1Y9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCLGGNSKT TEDQGVDEKE RREANKKIEK QLQKERLAYK ATHRLLLLGA
60 70 80 90 100
GESGKSTIVK QMRILHVNGF NPEEKKQKIL DIRKNVKDAI VTIVSAMSTI
110 120 130 140 150
IPPVPLANPE NQFRSDYIKS IAPITDFEYS QEFFDHVKKL WDDEGVKACF
160 170 180 190 200
ERSNEYQLID CAQYFLERID SVSLVDYTPT DQDLLRCRVL TSGIFETRFQ
210 220 230 240 250
VDKVNFHMFD VGGQRDERRK WIQCFNDVTA IIYVAACSSY NMVIREDNNT
260 270 280 290 300
NRLRESLDLF ESIWNNRWLR TISIILFLNK QDMLAEKVLA GKSKIEDYFP
310 320 330 340 350
EYANYTVPED ATPDAGEDPK VTRAKFFIRD LFLRISTATG DGKHYCYPHF
360 370 380
TCAVDTENIR RVFNDCRDII QRMHLKQYEL L
Length:381
Mass (Da):44,308
Last modified:December 4, 2007 - v1
Checksum:i9A73D2982FF9C9A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290054 mRNA. Translation: BAF82743.1.
AK313902 mRNA. Translation: BAG36625.1.
CH471113 Genomic DNA. Translation: EAX01574.1.
RefSeqiNP_001135811.1. NM_001142339.2.
NP_001248372.1. NM_001261443.1.
UniGeneiHs.136295.
Hs.741448.

Genome annotation databases

GeneIDi2774.
KEGGihsa:2774.

Similar proteinsi

Entry informationi

Entry nameiA8K1Y9_HUMAN
AccessioniPrimary (citable) accession number: A8K1Y9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: September 27, 2017
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.