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Protein
Submitted name:

cDNA FLJ78200, highly similar to Homo sapiens PSP24

Gene

GPR63

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ78200, highly similar to Homo sapiens PSP24Imported
Submitted name:
cDNA, FLJ94093, Homo sapiens G protein-coupled receptor 63 (GPR63), mRNAImported
Gene namesi
Name:GPR63Imported
ORF Names:hCG_1646313Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000112218.8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei82 – 107HelicalSequence analysisAdd BLAST26
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Transmembranei159 – 177HelicalSequence analysisAdd BLAST19
Transmembranei197 – 215HelicalSequence analysisAdd BLAST19
Transmembranei241 – 266HelicalSequence analysisAdd BLAST26
Transmembranei312 – 335HelicalSequence analysisAdd BLAST24
Transmembranei355 – 373HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28907

PTM / Processingi

Proteomic databases

PRIDEiA8K1C4

Expressioni

Gene expression databases

BgeeiENSG00000112218
ExpressionAtlasiA8K1C4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini98 – 371G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST274

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
HOVERGENiHBG051812
KOiK04321
OMAiYYWRIKK
OrthoDBiEOG091G07RP

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A8K1C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFSAVLTAF HTGTSNTTFV VYENTYMNIT LPPPFQHPDL SPLLRYSFET
60 70 80 90 100
MAPTGLSSLT VNSTAVPTTP AAFKSLNLPL QITLSAIMIF ILFVSFLGNL
110 120 130 140 150
VVCLMVYQKA AMRSAINILL ASLAFADMLL AVLNMPFALV TILTTRWIFG
160 170 180 190 200
KFFCRVSAMF FWLFVIEGVA ILLIISIDRF LIIVQRQDKL NPYRAKVLIA
210 220 230 240 250
VSWATSFCVA FPLAVGNPDL QIPSRAPQCV FGYTTNPGYQ AYVILISLIS
260 270 280 290 300
FFIPFLVILY SFMGILNTLR HNALRIHSYP EGICLSQASK LGLMSLQRPF
310 320 330 340 350
QMSIDMGFKT RAFTTILILF AVFIVCWAPF TTYSLVATFS KHFYYQHNFF
360 370 380 390 400
EISTWLLWLC YLKSALNPLI YYWRIKKFHD ACLDMMPKSF KFLPQLPGHT
410
KRRIRPSAVY VCGEHRTVV
Length:419
Mass (Da):47,578
Last modified:December 4, 2007 - v1
Checksum:i17418CD0AE1D6C8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ348260 mRNA Translation: ACI96304.1
AK289839 mRNA Translation: BAF82528.1
AK313535 mRNA Translation: BAG36312.1
CH471051 Genomic DNA Translation: EAW48502.1
RefSeqiNP_001137429.1, NM_001143957.2
NP_110411.1, NM_030784.3
XP_006715633.1, XM_006715570.3
XP_011534455.1, XM_011536153.2
XP_011534456.1, XM_011536154.2
XP_011534457.1, XM_011536155.2
XP_011534459.1, XM_011536157.2
XP_011534461.1, XM_011536159.2
XP_016866823.1, XM_017011334.1
UniGeneiHs.221364

Genome annotation databases

GeneIDi81491
KEGGihsa:81491

Similar proteinsi

Entry informationi

Entry nameiA8K1C4_HUMAN
AccessioniPrimary (citable) accession number: A8K1C4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 20, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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