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Protein

Putative homeobox protein Meis3-like 2

Gene

MEIS3P2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi245 – 307HomeoboxPROSITE-ProRule annotationAdd BLAST63

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciZFISH:G66-33685-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative homeobox protein Meis3-like 2
Gene namesi
Name:MEIS3P2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:17638. MEIS3P2.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003470561 – 358Putative homeobox protein Meis3-like 2Add BLAST358

Proteomic databases

MaxQBiA8K0S8.
PRIDEiA8K0S8.

PTM databases

iPTMnetiA8K0S8.
PhosphoSitePlusiA8K0S8.

Expressioni

Organism-specific databases

HPAiHPA046699.

Structurei

3D structure databases

ProteinModelPortaliA8K0S8.
SMRiA8K0S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TALE/MEIS homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

HOVERGENiHBG055193.
InParanoidiA8K0S8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR032453. PKNOX/Meis_N.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF16493. Meis_PKNOX_N. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K0S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRYDELPH YPSIADGPAA LAGFPEAVPA APGPYGPHRP PQPLPPGLDS
60 70 80 90 100
DGLKRDKDEI YGHPLFPLLA LVFEKCELAT CSPRDGAGAG LGTPRGGDVC
110 120 130 140 150
SSDSFNEDNT AFAKQVRSER PFFSSNPELD NLMIQAIQVL RFHLLELEKG
160 170 180 190 200
KMPIDLVIED RDGGCREDFE DYPASCLSLP DQNNIWIRDH EDSGSVHLGT
210 220 230 240 250
PGPSSGGLAS QSGDNSSDQG VGLDTSVASP SSGGEDEDLD QEPRRNKKRG
260 270 280 290 300
IFPKVATNIM RAWLFQHLWH PYPSEEQKKQ LVQDTGLTIL QVNNWFINAR
310 320 330 340 350
RRMVQPMIDQ SNRIGQGAAF SPEGQPIGGY TETEPHVAFR PPASVGMSLN

LEGEWHYL
Length:358
Mass (Da):39,220
Last modified:December 4, 2007 - v1
Checksum:i4A8D7C4EC758FFE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289643 mRNA. Translation: BAF82332.1.
AC087499 Genomic DNA. No translation available.
UniGeneiHs.462484.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289643 mRNA. Translation: BAF82332.1.
AC087499 Genomic DNA. No translation available.
UniGeneiHs.462484.

3D structure databases

ProteinModelPortaliA8K0S8.
SMRiA8K0S8.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiA8K0S8.
PhosphoSitePlusiA8K0S8.

Proteomic databases

MaxQBiA8K0S8.
PRIDEiA8K0S8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiMEIS3P2.
HGNCiHGNC:17638. MEIS3P2.
HPAiHPA046699.
neXtProtiNX_A8K0S8.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG055193.
InParanoidiA8K0S8.

Enzyme and pathway databases

BioCyciZFISH:G66-33685-MONOMER.

Miscellaneous databases

PROiA8K0S8.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR009057. Homeodomain-like.
IPR032453. PKNOX/Meis_N.
[Graphical view]
PfamiPF05920. Homeobox_KN. 1 hit.
PF16493. Meis_PKNOX_N. 1 hit.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiME3L2_HUMAN
AccessioniPrimary (citable) accession number: A8K0S8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: December 4, 2007
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Although defined as a pseudogene by HGNC, it is clearly expressed.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.