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Protein
Submitted name:

Osteoglycin (Osteoinductive factor, mimecan), isoform CRA_a

Gene

OGN

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Osteoglycin (Osteoinductive factor, mimecan), isoform CRA_aImported
Submitted name:
cDNA FLJ78199, highly similar to Homo sapiens osteoglycin (osteoinductive factor, mimecan) (OGN), transcript variant 3, mRNAImported
Submitted name:
cDNA PSEC0219 fis, clone HEMBA1005229, highly similar to MimecanImported
Gene namesi
Name:OGNImported
ORF Names:hCG_31130Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31913.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500875477420 – 298Sequence analysisAdd BLAST279

Expressioni

Gene expression databases

BgeeiENSG00000106809.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000262551.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOVERGENiHBG006850.
KOiK08126.
OMAiRMDEIRM.
OrthoDBiEOG091G0E49.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR027211. Mimecan.
[Graphical view]
PANTHERiPTHR24373:SF122. PTHR24373:SF122. 1 hit.
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 4 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K0R3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTLQSTLLL LLLVPLIKPA PPTQQDSRII YDYGTDNFEE SIFSQDYEDK
60 70 80 90 100
YLDGKNIKEK ETVIIPNEKS LQLQKDEAIT PLPPKKENDE MPTCLLCVCL
110 120 130 140 150
SGSVYCEEVD IDAVPPLPKE SAYLYARFNK IKKLTAKDFA DIPNLRRLDF
160 170 180 190 200
TGNLIEDIED GTFSKLSLLE ELSLAENQLL KLPVLPPKLT LFNAKYNKIK
210 220 230 240 250
SRGIKANAFK KLNNLTFLYL DHNALESVPL NLPESLRVIH LQFNNIASIT
260 270 280 290
DDTFCKANDT SYIRDRIEEI RLEGNPIVLG KHPNSFICLK RLPIGSYF
Length:298
Mass (Da):33,922
Last modified:December 4, 2007 - v1
Checksum:iF4590785C3849F83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289628 mRNA. Translation: BAF82317.1.
AK075521 mRNA. Translation: BAG52162.1.
CH471089 Genomic DNA. Translation: EAW62818.1.
CH471089 Genomic DNA. Translation: EAW62819.1.
CH471089 Genomic DNA. Translation: EAW62820.1.
RefSeqiNP_054776.1. NM_014057.4.
NP_148935.1. NM_033014.3.
UniGeneiHs.109439.
Hs.617761.

Genome annotation databases

GeneIDi4969.
KEGGihsa:4969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289628 mRNA. Translation: BAF82317.1.
AK075521 mRNA. Translation: BAG52162.1.
CH471089 Genomic DNA. Translation: EAW62818.1.
CH471089 Genomic DNA. Translation: EAW62819.1.
CH471089 Genomic DNA. Translation: EAW62820.1.
RefSeqiNP_054776.1. NM_014057.4.
NP_148935.1. NM_033014.3.
UniGeneiHs.109439.
Hs.617761.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000262551.

Protocols and materials databases

DNASUi4969.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4969.
KEGGihsa:4969.

Organism-specific databases

CTDi4969.
PharmGKBiPA31913.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
HOVERGENiHBG006850.
KOiK08126.
OMAiRMDEIRM.
OrthoDBiEOG091G0E49.

Miscellaneous databases

GenomeRNAii4969.

Gene expression databases

BgeeiENSG00000106809.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiIPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR027211. Mimecan.
[Graphical view]
PANTHERiPTHR24373:SF122. PTHR24373:SF122. 1 hit.
PfamiPF13855. LRR_8. 1 hit.
[Graphical view]
SMARTiSM00369. LRR_TYP. 4 hits.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiPS51450. LRR. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA8K0R3_HUMAN
AccessioniPrimary (citable) accession number: A8K0R3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: November 30, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.