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Protein
Submitted name:

Interferon alpha-inducible protein 27, mitochondrial

Gene

IFI27

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon alpha-inducible protein 27, mitochondrialImported
Submitted name:
Interferon, alpha-inducible protein 27, isoform CRA_aImported
Submitted name:
cDNA FLJ78595, highly similar to Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNAImported
Submitted name:
cDNA, FLJ92370, highly similar to Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNAImported
Gene namesi
Name:IFI27Imported
ORF Names:hCG_22330Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

HGNCiHGNC:5397. IFI27.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 6129HelicalSequence analysisAdd
BLAST
Transmembranei73 – 9523HelicalSequence analysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29643.

Expressioni

Gene expression databases

ExpressionAtlasiA8K0H0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000298902.

Structurei

3D structure databases

SMRiA8K0H0. Positions 51-116.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410JFVP. Eukaryota.
ENOG410Z2RX. LUCA.
GeneTreeiENSGT00390000002592.
HOGENOMiHOG000112988.
HOVERGENiHBG099821.
OMAiGVEAVPM.

Family and domain databases

InterProiIPR009311. IFI6/IFI27.
[Graphical view]
PANTHERiPTHR16932. PTHR16932. 1 hit.
PfamiPF06140. Ifi-6-16. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A8K0H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEASALTSSA VTSVAKVVRV ASGSAVVLPL ARIATVVIGG VVAMAAVPMV
60 70 80 90 100
LSAMGFTAAG IASSSIAAKM MSAAAIANGG GVASGSLVAT LQSLGATGLS
110 120
GLTKFILGSI GSAIAAVIAR FY
Length:122
Mass (Da):11,542
Last modified:December 4, 2007 - v1
Checksum:iA424B2EDEAA678A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079302 Genomic DNA. No translation available.
AL121838 Genomic DNA. No translation available.
KF573698 Genomic DNA. No translation available.
AK289535 mRNA. Translation: BAF82224.1.
AK312089 mRNA. Translation: BAG35025.1.
CH471061 Genomic DNA. Translation: EAW81556.1.
CH471061 Genomic DNA. Translation: EAW81557.1.
CH471061 Genomic DNA. Translation: EAW81558.1.
RefSeqiNP_001123552.1. NM_001130080.2.
NP_001275881.1. NM_001288952.1.
NP_001275885.1. NM_001288956.1.
UniGeneiHs.532634.

Genome annotation databases

EnsembliENST00000612813; ENSP00000483430; ENSG00000165949.
ENST00000612838; ENSP00000483932; ENSG00000275214.
ENST00000613997; ENSP00000484089; ENSG00000275214.
ENST00000616764; ENSP00000477753; ENSG00000165949.
ENST00000621160; ENSP00000483498; ENSG00000165949.
ENST00000627111; ENSP00000486608; ENSG00000275214.
GeneIDi3429.
KEGGihsa:3429.
UCSCiuc032bkg.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL079302 Genomic DNA. No translation available.
AL121838 Genomic DNA. No translation available.
KF573698 Genomic DNA. No translation available.
AK289535 mRNA. Translation: BAF82224.1.
AK312089 mRNA. Translation: BAG35025.1.
CH471061 Genomic DNA. Translation: EAW81556.1.
CH471061 Genomic DNA. Translation: EAW81557.1.
CH471061 Genomic DNA. Translation: EAW81558.1.
RefSeqiNP_001123552.1. NM_001130080.2.
NP_001275881.1. NM_001288952.1.
NP_001275885.1. NM_001288956.1.
UniGeneiHs.532634.

3D structure databases

SMRiA8K0H0. Positions 51-116.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000298902.

Protocols and materials databases

DNASUi3429.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000612813; ENSP00000483430; ENSG00000165949.
ENST00000612838; ENSP00000483932; ENSG00000275214.
ENST00000613997; ENSP00000484089; ENSG00000275214.
ENST00000616764; ENSP00000477753; ENSG00000165949.
ENST00000621160; ENSP00000483498; ENSG00000165949.
ENST00000627111; ENSP00000486608; ENSG00000275214.
GeneIDi3429.
KEGGihsa:3429.
UCSCiuc032bkg.2. human.

Organism-specific databases

CTDi3429.
HGNCiHGNC:5397. IFI27.
PharmGKBiPA29643.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JFVP. Eukaryota.
ENOG410Z2RX. LUCA.
GeneTreeiENSGT00390000002592.
HOGENOMiHOG000112988.
HOVERGENiHBG099821.
OMAiGVEAVPM.

Miscellaneous databases

ChiTaRSiIFI27. human.
GenomeRNAii3429.

Gene expression databases

ExpressionAtlasiA8K0H0. baseline and differential.

Family and domain databases

InterProiIPR009311. IFI6/IFI27.
[Graphical view]
PANTHERiPTHR16932. PTHR16932. 1 hit.
PfamiPF06140. Ifi-6-16. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: CerebellumImported.
  5. "NEDO functional analysis of protein and research application project."
    Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T.
    Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: StomachImported.
  6. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
  7. Ensembl
    Submitted (JUN-2015) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiA8K0H0_HUMAN
AccessioniPrimary (citable) accession number: A8K0H0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 4, 2007
Last sequence update: December 4, 2007
Last modified: June 8, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.