A8JRI1 (A8JRI1_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hephaestus, isoform L EMBL ABW08816.1

Gene names

Name:	heph FlyBase FBgn0011224
ORF Names:	Dmel_CG31000 EMBL ABW08816.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	622 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	imaginal disc-derived wing margin morphogenesis Inferred from mutant phenotype. Source: FlyBase imaginal disc-derived wing vein morphogenesis Inferred from mutant phenotype. Source: FlyBase mRNA processing Inferred from electronic annotation. Source: InterPro negative regulation of oskar mRNA translation Inferred from mutant phenotype. Source: FlyBase oocyte microtubule cytoskeleton polarization Inferred from mutant phenotype. Source: FlyBase sperm individualization Inferred from mutant phenotype. Source: FlyBase
Cellular component	cytoplasm Inferred from direct assay. Source: FlyBase nucleus Inferred from electronic annotation. Source: InterPro ribonucleoprotein complex Inferred from direct assay. Source: FlyBase
Molecular function	mRNA 3'-UTR binding Inferred from direct assay. Source: FlyBase nucleotide binding Inferred from electronic annotation. Source: InterPro translation repressor activity, nucleic acid binding Inferred from mutant phenotype. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8JRI1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: DF4AAFFC82315201	FASTA	622	67,324
	10 20 30 40 50 60 MMSCPIPMPM PISSLHKSEF EPVNIGVKVR IDEQYIYKLN YLRGSDELLS QAAVMAPASD 70 80 90 100 110 120 NNNQDLATKK AKLEPGTVLA GGIAKASKVI HLRNIPNESG EADVIALGIP FGRVTNVLVL 130 140 150 160 170 180 KGKNQAFIEM ADEISATSMV SCYTVTPPQM RGRMVYVQFS NHRELKTDQG HNNSTAHSDY 190 200 210 220 230 240 SVQSPASGSP LPLSAAANAT SNNANSSSDS NSAMGILQNT SAVNAGGNTN AAGGPNTVLR 250 260 270 280 290 300 VIVESLMYPV SLDILHQIFQ RYGKVLKIVT FTKNNSFQAL IQYPDANSAQ HAKSLLDGQN 310 320 330 340 350 360 IYNGCCTLRI DNSKLTALNV KYNNDKSRDF TNPALPPGEP GVDIMPTAGG LMNTNDLLLI 370 380 390 400 410 420 AARQRPSLSG DKIVNGLGAP GVLPPFALGL GTPLTGGYNN ALPNLAAFSL ANSGALQTTA 430 440 450 460 470 480 PAMRGYSNVL LVSNLNEEMV TPDALFTLFG VYGDVQRVKI LYNKKDSALI QMAEPQQAYL 490 500 510 520 530 540 AMSHLDKLRL WGKPIRVMAS KHQAVQLPKE GQPDAGLTRD YSQNPLHRFK KPGSKNYQNI 550 560 570 580 590 600 YPPSATLHLS NIPSSCSEDD IKEAFTSNSF EVKAFKFFPK DRKMALLQLL SVEEAVLALI 610 620 KMHNHQLSES NHLRVSFSKS NI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: ABW08816.1.
RefSeq	NP_001097992.1. NM_001104522.2.
UniGene	Dm.19417.
3D structure databases
ProteinModelPortal	A8JRI1.
SMR	A8JRI1. Positions 60-169, 233-339, 427-622.
ModBase	Search...
Protein-protein interaction databases
STRING	A8JRI1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0112864; FBpp0111777; FBgn0011224.
GeneID	48571.
KEGG	dme:Dmel_CG31000.
UCSC	CG31000-RL. d. melanogaster.
Organism-specific databases
CTD	9843.
FlyBase	FBgn0011224. heph.
Phylogenomic databases
OrthoDB	EOG4X69QV.
Gene expression databases
Bgee	A8JRI1.
Family and domain databases
InterPro	IPR006536. HnRNP-L_PTB. IPR012677. Nucleotide-bd_a/b_plait. IPR000504. RRM_dom. [Graphical view]
Gene3D	G3DSA:3.30.70.330. a_b_plait_nuc_bd. 4 hits.
KO	K14948.
Pfam	PF00076. RRM_1. 2 hits. [Graphical view]
SMART	SM00360. RRM. 4 hits. [Graphical view]
TIGRFAMs	TIGR01649. HnRNP-L_PTB. 1 hit.
PROSITE	PS50102. RRM. 4 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	839481.

Entry information

Entry name

A8JRI1_DROME

Accession

Primary (citable) accession number: A8JRI1

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)