MSD2

Functionⁱ

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityⁱ

2 superoxide + 2 H⁺ = O₂ + H₂O₂.UniRule annotation

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	51	Divalent metal cationUniRule annotation	1
Metal bindingⁱ	99	Divalent metal cationUniRule annotation	1
Metal bindingⁱ	184	Divalent metal cationUniRule annotation	1
Metal bindingⁱ	188	Divalent metal cationUniRule annotation	1

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
superoxide dismutase activity Source: UniProtKB-EC

Complete GO annotation...

Keywordsⁱ

Molecular function	OxidoreductaseUniRule annotation
Ligand	Metal-bindingUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesⁱ	Name:MSD2Imported ORF Names:CHLREDRAFT_193511Imported
Organismⁱ	Chlamydomonas reinhardtii (Chlamydomonas smithii)Imported
Taxonomic identifierⁱ	3055 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Chlorophyta › Chlorophyceae › Chlamydomonadales › Chlamydomonadaceae › Chlamydomonas
Proteomesⁱ	UP000006906 Componentⁱ: Unassembled WGS sequence

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	3055.EDO98932.

STRINGⁱ

3055.EDO98932.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	28 – 106	Sod_Fe_NInterPro annotationAdd BLAST		79
Domainⁱ	115 – 217	Sod_Fe_CInterPro annotationAdd BLAST		103

Sequence similaritiesⁱ

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0876. Eukaryota. COG0605. LUCA.
KEGG Orthology (KO) More...KOⁱ	K04564.
OMAⁱ	KWGSFDK.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit.
PIRSFⁱ	PIRSF000349. SODismutase. 1 hit.
PRINTSⁱ	PR01703. MNSODISMTASE.
SUPFAMⁱ	SSF46609. SSF46609. 1 hit. SSF54719. SSF54719. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00088. SOD_MN. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A8JAX1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLARVALGLA RDGQSAVPTM TRAMSSVKLP DLPYSYGALE PYISGQIMEL 
        60         70         80         90        100
HHSKHHATYV ANLNKALEQQ AEAEHKGDVA KLISLQSAIK FNGGGHVNHD 
       110        120        130        140        150
IFWTNLCPHK EWQPPSGDLK ALIEAQWKTL DNFTTTFSAQ TAAVQGSGWG 
       160        170        180        190        200
WLGYNKATHK LEVVTLPNQD PLSVTGLVPL LGIDVWEHAY YLQYKNVRPD 
       210        220 
YLKAIWNIVN WQNVEQRLAA AKK

Length:223

Mass (Da):24,852

Last modified:December 4, 2007 - v1

Checksum:ⁱ1E0F0A1A29E7F1B1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	GQ413966 mRNA. Translation: ACV41091.1. DS496151 Genomic DNA. Translation: EDO98932.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_001699077.1. XM_001699025.1.
UniGeneⁱ	Cre.2383.

Genome annotation databases

EnsemblPlantsⁱ	EDO98932; EDO98932; CHLREDRAFT_193511.
GeneIDⁱ	5724629.
Grameneⁱ	EDO98932; EDO98932; CHLREDRAFT_193511.
KEGGⁱ	cre:CHLREDRAFT_193511.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	GQ413966 mRNA. Translation: ACV41091.1. DS496151 Genomic DNA. Translation: EDO98932.1.
NCBI Reference Sequences More...RefSeqⁱ	XP_001699077.1. XM_001699025.1.
UniGeneⁱ	Cre.2383.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	3055.EDO98932.

STRINGⁱ

3055.EDO98932.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	EDO98932; EDO98932; CHLREDRAFT_193511.
GeneIDⁱ	5724629.
Grameneⁱ	EDO98932; EDO98932; CHLREDRAFT_193511.
KEGGⁱ	cre:CHLREDRAFT_193511.

Phylogenomic databases

eggNOGⁱ	KOG0876. Eukaryota. COG0605. LUCA.
KEGG Orthology (KO) More...KOⁱ	K04564.
OMAⁱ	KWGSFDK.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit.
PIRSFⁱ	PIRSF000349. SODismutase. 1 hit.
PRINTSⁱ	PR01703. MNSODISMTASE.
SUPFAMⁱ	SSF46609. SSF46609. 1 hit. SSF54719. SSF54719. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00088. SOD_MN. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A8JAX1_CHLRE
Accessionⁱ	A8JAX1Primary (citable) accession number: A8JAX1
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 4, 2007
	Last sequence update:	December 4, 2007
	Last modified:	June 7, 2017
	This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - A8JAX1 (A8JAX1_CHLRE)

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Superoxide dismutase

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Functionⁱ

Catalytic activityⁱ

Sites

GO - Molecular functionⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A8JAX1 (A8JAX1_CHLRE)

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Superoxide dismutase

MSD2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ