Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ADP-ribosylation factor-like protein 13B

Gene

ARL13

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 33GTP1 Publication8
Nucleotide bindingi69 – 73GTPBy similarity5
Nucleotide bindingi128 – 131GTP1 Publication4

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ADP-ribosylation factor-like protein 13B
Short name:
CrArl13B
Gene namesi
Name:ARL13
ORF Names:CHLREDRAFT_195529
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas
Proteomesi
  • UP000006906 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cell projection, Cilium, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004259001 – 527ADP-ribosylation factor-like protein 13BAdd BLAST527

Proteomic databases

PaxDbiA8INQ0.

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

STRINGi3055.EDP05163.

Structurei

Secondary structure

1527
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi18 – 25Combined sources8
Helixi32 – 39Combined sources8
Beta strandi51 – 60Combined sources10
Beta strandi63 – 70Combined sources8
Turni74 – 76Combined sources3
Helixi77 – 86Combined sources10
Beta strandi88 – 95Combined sources8
Helixi99 – 101Combined sources3
Helixi102 – 114Combined sources13
Helixi116 – 118Combined sources3
Beta strandi123 – 128Combined sources6
Helixi138 – 144Combined sources7
Helixi147 – 149Combined sources3
Beta strandi154 – 158Combined sources5
Helixi172 – 205Combined sources34
Helixi206 – 210Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4M9QX-ray2.50A/B/C18-242[»]
5DI3X-ray2.50B18-278[»]
ProteinModelPortaliA8INQ0.
SMRiA8INQ0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Contains an incomplete active site due to the presence of a Gly residue in position 72 instead of a Gln, probably explaining the inability to hydrolyze GTP.1 Publication

Sequence similaritiesi

Belongs to the small GTPase superfamily. Arf family.Curated

Phylogenomic databases

eggNOGiKOG0070. Eukaryota.
COG1100. LUCA.
InParanoidiA8INQ0.
KOiK07962.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR024156. Small_GTPase_ARF.
IPR006689. Small_GTPase_ARF/SAR.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51417. ARF. 1 hit.

Sequencei

Sequence statusi: Complete.

A8INQ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFGLLVNFYR FCRKKTERKI TIALLGLDNA GKTTLLNSIQ GEVDRDTTPT
60 70 80 90 100
FGFNSTTLNE GKYKIEVFDL GGGKNIRGVW KKYLAEVHAI VYVVDAADPG
110 120 130 140 150
RFEESKMTMA EVLENQFMRD KPICIFANKQ DLPTAAPAAE VVKGLGLATC
160 170 180 190 200
RNSHNVFPCT AKMPAGQDVD HRLRDGLKWL VGTVDREFGR LDPRVQTEAE
210 220 230 240 250
EVRQEEARKK KEREERLRKQ REERLRQQKE EEERAREVEK ENELHDGKAP
260 270 280 290 300
SLLAAGGGVV GAAAAGVNGV MVDEQQELRP PGQHQEAPEA LGLHNGLALG
310 320 330 340 350
LPHTIESPGK FPPPPRRPLE AHPASDLRLV APDQGVSSAS GGPGLGAMPS
360 370 380 390 400
GSHGGGGVPP QPASLPHVRA ALPPLPPSAP QPSDAGVGSS GSASRHPGAH
410 420 430 440 450
SSSAAAPPNV ASGAAAEDGP EPDAAGTAAG EAGSGSVFAP RPASAGGGGP
460 470 480 490 500
GSRGSGSGMT PDARELGSGG VESGEGTPAR LRAGAQQASD GGHGNSKGSF
510 520
SLVHTSNKVV PVAPDLRAGI PGAPNDA
Length:527
Mass (Da):54,793
Last modified:December 4, 2007 - v1
Checksum:iF73AB844C85833DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS496119 Genomic DNA. Translation: EDP05163.1.
RefSeqiXP_001691430.1. XM_001691378.1.

Genome annotation databases

EnsemblPlantsiEDP05163; EDP05163; CHLREDRAFT_195529.
GeneIDi5716967.
GrameneiEDP05163; EDP05163; CHLREDRAFT_195529.
KEGGicre:CHLREDRAFT_195529.

Entry informationi

Entry nameiARL13_CHLRE
AccessioniPrimary (citable) accession number: A8INQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 19, 2014
Last sequence update: December 4, 2007
Last modified: May 10, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families