A8IKG2 (A8IKG2_AZOC5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	AZC_3904

Organism

Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP] EMBL BAF89902.1

Taxonomic identifier

438753 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Azorhizobium

Protein attributes

Sequence length	1175 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A8IKG2 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 86EBE65860A22405	FASTA	1,175	130,293
	10 20 30 40 50 60 MPCAIRADRA RLGRIQPTTE RRRPMSSYAE LAAATNFSFL HGASHPAEMV ARAMELGLTG 70 80 90 100 110 120 IGIADRNTVA GVVRAYAAVR DAPEKARAAL AAAKERRGEL PELTEAEKTA CEVKLKLAVG 130 140 150 160 170 180 TRFVFADGTP DIIAYPEDRK AWGRITRLLT RGNLRAVKGG CILNFEDLLE HLEGLLLIVM 190 200 210 220 230 240 PQSTAAPQEA HRAPVGYDFA DQEEAEDAPP EAGGDPEASG VRSFGHLALV PPPAPTRPEG 250 260 270 280 290 300 LEAVLARLAA EAPGRVWLGA ALHRRGSDGR RLARLRRLAS AARVPLLATN DPLYASEDRR 310 320 330 340 350 360 PLHDVLTCIR EGTTLEAAGR RLEANGERHI RTPNEMARLF RACPEALLET QCLLERIGFS 370 380 390 400 410 420 LGDLKYEYPH EPVPEGWAPQ DWLEHLVTEA AHARYGAVLP EKVKALLAEE FALIRQEKFA 430 440 450 460 470 480 YYFLTVHDLV RFARAQEPPI LCQGRGSAAN SIVCFLLGIT SVDPVQYNLL FSRFVSEDRG 490 500 510 520 530 540 EPPDIDVDFE HERREEVMQY VYRRYGRHRA GIAATVIHYR GRSAVREVSK VLGLTEDVSS 550 560 570 580 590 600 RLAGLVWGSH SGDMDARRMQ EAGFDPDNPE MARLRFILEP LLSAPFPRHL SQHVGGFVLT 610 620 630 640 650 660 QDRLDETVPI HHAAMADRSF IEWDKDDIDV LGLMKVDVLA LGMLTCIRKA FELMRAHGLG 670 680 690 700 710 720 EKTLEVDLAS DDEAVYDMLC KGDSIGVFQV ESRAQINMLP RLKPRKLYDL TIQVAIVRPG 730 740 750 760 770 780 PIEGEMVHPY LRRRAGLEDW SFPSPTPPHP ANELHDLLGE TYGVPLFQEQ AMKLAIVAAD 790 800 810 820 830 840 FTPRQANGLR RAMATFRNPG TIHSFRAMMV EGMVRRGYTR DFALRCFKQI EGFGSYGFPE 850 860 870 880 890 900 SHALSFARLV YVSAWIKCHH PAVFACALLN SQPMGFYAPA QIVRDAREHG VEVRPVEVNA 910 920 930 940 950 960 SEWDNTLEEA ANGRLALRLG FRQVEGFREL WAAEIVAARA SGPFSSVEDL ARRAHLPRAG 970 980 990 1000 1010 1020 LRLLADADAL RSLGLERRDA LWEVRRTPEG ELPLFAAARA GELKAERDLP LPAMSAAEQV 1030 1040 1050 1060 1070 1080 AVDYQTTRLS LKGHPMAFLR PLFAERGVLS SAQTAAARAG AKVRTAGIVL IRQRPGKGNA 1090 1100 1110 1120 1130 1140 IFVTLEDETG ITNVLIWARL FETLRLPVMA SRLMLVHGEV QRSREGVVHL MASHVEDCTP 1150 1160 1170 VLDGHFFDST AGAHPVHRAA HPRDVRILPR SRDFH

References

[1]

"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571." Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009384 Genomic DNA. Translation: BAF89902.1.
RefSeq	YP_001526820.1. NC_009937.1.
3D structure databases
ProteinModelPortal	A8IKG2.
ModBase	Search...
Protein-protein interaction databases
STRING	A8IKG2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5691682.
GenomeReviews	Gene locus AZC_3904 in contig AP009384_GR.
KEGG	azc:AZC_3904.
PATRIC	21024665. VBIAzoCau17976_4072.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK2795724.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A8IKG2_AZOC5

Accession

Primary (citable) accession number: A8IKG2

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)