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A8IEU9 (GLSA_AZOC5) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase

EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:AZC_3538
OrganismAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571) [Complete proteome] [HAMAP]
Taxonomic identifier438753 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00313

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309Glutaminase HAMAP-Rule MF_00313
PRO_0000336024

Sites

Binding site641Substrate By similarity
Binding site1141Substrate By similarity
Binding site1601Substrate By similarity
Binding site1671Substrate By similarity
Binding site1911Substrate By similarity
Binding site2431Substrate By similarity
Binding site2611Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A8IEU9 [UniParc].

Last modified December 4, 2007. Version 1.
Checksum: 944736C746EB0E78

FASTA30932,659
        10         20         30         40         50         60 
MPKLNDVVAE IAADLAKATE RGAVATYIPM LAEVPINQFG MAVVTADGET ILAGDADTVF 

        70         80         90        100        110        120 
SIQSISKVFT LTLALGQIGD ALWTRVGKEP SGNAFNSIVQ LEYEHGIPRN PFINAGAIVV 

       130        140        150        160        170        180 
ADAMLSGHQP REALGAILRF VRFVAADESI TIDEAVARSE KETGFRNTAL ANYMRSFGVL 

       190        200        210        220        230        240 
RHPVDHALGV YFHQCAIAMS CRHLARAGRY LAFSGRLTPE GPSVVASERA RRIAALMLTC 

       250        260        270        280        290        300 
GHYDGSGDFA FRVGLPGKSG VGGGILAIAP GKASIAVWSP GLDPHGNSLL GSIALERLAK 


AMRWSVFAG 

« Hide

References

[1]"Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43989 / DSM 5975 / ORS 571.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009384 Genomic DNA. Translation: BAF89536.1.
RefSeqYP_001526454.1. NC_009937.1.

3D structure databases

ProteinModelPortalA8IEU9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING438753.AZC_3538.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF89536; BAF89536; AZC_3538.
GeneID5690350.
KEGGazc:AZC_3538.
PATRIC21023907. VBIAzoCau17976_3699.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMAQRARRIN.
OrthoDBEOG6N94BK.

Enzyme and pathway databases

BioCycACAU438753:GJF3-3577-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. SSF56601. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_AZOC5
AccessionPrimary (citable) accession number: A8IEU9
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 4, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families